Polyether Polyketides

DBCAT005896Pharmacologic class

Polycyclic polyketides with distinctive ladder shaped multiple polyether motifs. In STREPTOMYCES polycyclic polyketide backbones are assembled by type I modular polyketide synthases which then are modified by epoxidase and epoxide hydrolase to achieve their stereochemistry. A DrugBank category of 6 drugs.

Drugs: Bryostatin 1
Calcimycin
Lasalocid
Monensin
Nigericin
Semduramicin

What you can answer from here — as of December 03, 2023

6DrugsEach linked to its full drug card

Listed above

14Drug targetsEvery drug–target pair in the class, with bond type

4Marketed productsAcross the regions we cover, with dosage forms and routes

2Routes of administrationHow the drugs in this class are given

Which targets do Polyether Polyketides share, and which companies have late-stage candidates in this class?

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