Ascaris lumbricoides infection (DBCOND0021877)

Identifiers

Synonyms

Ascariasis, unspecified / [X]Ascariasis, unspecified / Ascariasis

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Levamisole	Levamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.	Neuronal acetylcholine receptor subunit alpha-3target Alkaline phosphatase, germ cell typetarget Acetylcholine receptor subunit alpha-type unc-38target Acetylcholine receptor subunit alpha-type unc-63target Acetylcholine receptor subunit beta-type lev-1target Acetylcholine receptor subunit beta-type unc-29target Alkaline phosphatase, tissue-nonspecific isozymetarget
Mebendazole	A benzimidazole anthelmintic used to treat helminth infections.	Tubulin alpha-1A chaintarget Tubulin beta-4B chaintarget Cytochrome P450 1A1enzyme Cytochrome P450 3A Subfamilyenzyme
Piperazine	A medication used to treat roundworm and pinworm.	Gamma-aminobutyric acid receptor subunit beta-3target Cytochrome P450 2D6enzyme

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05783544	Impact of A. Lumbricoides on Pulmonary Aspergillosis Development	No drug interventions	prevention	Not Available	recruiting
NCT05372068	Cement flooRs AnD chiLd hEalth (CRADLE)	No drug interventions	prevention	Not Available	recruiting
NCT05914363	Evaluating Impact of Improved Floors on Health	Albendazole	prevention	Not Available	recruiting