NCT01188421
Medications Development for Drug Abuse Disorders No drug interventions treatment 1 / 2 completed NCT02152397
Safety and Health Intervention Project No drug interventions prevention Not Available completed NCT02854800
Smoking Cessation & Opioid Dependence Treatment Integration treatment 2 / 3 completed NCT02920775
Monitoring Patterns of Prescribing to Identify Changes in Access to ER/LA Opioid Analgesics No drug interventions Not Available Not Available unknown_status NCT02925806
Evaluation of Drug Utilization Patterns for Extended Release/Long Acting Opioids and Comparator Products No drug interventions Not Available Not Available unknown_status NCT01846481
A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse No drug interventions treatment 2 completed NCT00271219
RCT Comparing Methadone and Buprenorphine in Pregnant Women No drug interventions treatment 3 completed NCT02737696
Computer-based Prescription Opioid Abuse Prevention for Adolescents No drug interventions prevention Not Available completed NCT01374763
A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery No drug interventions treatment 4 completed NCT02920762
Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers No drug interventions Not Available Not Available unknown_status NCT02357901
Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine No drug interventions treatment 3 completed NCT01582347
Transfer of Subjects From Subutex/Suboxone to RBP-6300 treatment 2 completed NCT01738503
Multiple Dose Pharmacokinetics Depot Buprenorphine in Opioid-Dependent Subjects No drug interventions treatment 2 completed NCT05803603
Social Work Assistance and Stipends for Housing (SASH) No drug interventions treatment Not Available completed NCT00000264
Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16 Not Available Not Available completed NCT01874964
Trial of Methadone Maintenance Versus Methadone Detox in Jail No drug interventions prevention Not Available unknown_status NCT04567784
Neuroimaging and CBD for Opiod Use Disorder No drug interventions treatment 2 recruiting NCT04933084
Pre-operative Education Modalities to Decrease Opioid Use No drug interventions prevention Not Available recruiting NCT00000279
Novel Medications for Opiate Detoxification - 4 treatment 2 completed NCT04499079
Alliances to Disseminate Addiction Prevention and Treatment (ADAPT) No drug interventions treatment Not Available enrolling_by_invitation NCT00000243
Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone treatment Not Available terminated NCT01894087
Safety & Prevention Outcomes Study No drug interventions prevention Not Available completed NCT00684554
Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial No drug interventions treatment 2 / 3 completed NCT00000354
Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3 treatment 1 completed NCT01848054
Study to Assess Efficacy and Safety of BNX Sublingual Tablets for the Induction of Treatment of Opioid Dependence treatment 3 completed NCT00000253
Effects of Nitrous Oxide: A Dose-Response Analysis - 5 Not Available Not Available completed NCT00000353
Trial of Buprenorphine/Naloxone for Opiate Dependence - 2 treatment 2 completed NCT03129347
Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers treatment 1 completed NCT03833245
Optimizing Pregnancy and Treatment Interventions for Moms 2.0 No drug interventions health_services_research Not Available completed NCT00000298
Buprenorphine Combination Tablet Feasibility - 1 treatment 2 completed NCT02698098
Comparative Evaluation of PUSPENs and C&Cs Not Available Not Available terminated NCT02667197
Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study 1B No drug interventions Not Available Not Available completed NCT03779997
Trial of Adherence App for Buprenorphine Treatment (TAAB) Study No drug interventions treatment Not Available completed NCT03604861
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery No drug interventions Not Available Not Available completed NCT00734461
Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse No drug interventions treatment 2 completed NCT03891628
Modified ABC: A Home-based Parenting Program for Opioid-dependent Mothers and Their Infants No drug interventions prevention Not Available completed NCT00015028
Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1 treatment 2 completed NCT05121428
Patients' Attitudes Toward and Experiences With Buprenorphine Treatment No drug interventions Not Available Not Available recruiting NCT00000193
Neurobiology of Opioid Dependence: 2 - 2 No drug interventions treatment 2 withdrawn NCT01733693
Neurocognitive Effects of Opiate Agonist Treatment treatment 4 completed NCT00473993
Hepatitis C Among Opioid Addicts in Opioid Maintenance Treatment in Zurich, Switzerland No drug interventions Not Available Not Available completed NCT00134888
Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence treatment Not Available completed NCT05336188
Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder No drug interventions treatment 2 enrolling_by_invitation NCT03098407
Opioid Dependence Treatment Therapies in Pregnancy other Not Available completed NCT00000207
Multicenter Clinical Trial of Buprenorphine - 3 treatment 3 completed NCT00218309
Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals Not Available Not Available completed NCT00000356
Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5 No drug interventions treatment 2 completed NCT00000237
Buprenorphine Detoxification - BBDVI - 19 treatment 2 completed NCT00698737
Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC) No drug interventions Not Available Not Available completed NCT02871232
Surveillance Monitoring of Opioid Abuse in Poison and Drug Treatment Centers No drug interventions Not Available Not Available unknown_status NCT00000252
Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4 treatment 2 completed NCT00000352
Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1 treatment 2 completed NCT00000300
Feasibility Study of Take-Home LAAM Medication - 3 No drug interventions treatment 4 completed NCT00061100
HIV Counseling Intervention for Methadone-Maintained Patients - 2 No drug interventions prevention 1 completed NCT02571400
Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study No drug interventions Not Available Not Available completed NCT00637000
Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone No drug interventions treatment 2 completed NCT00135759
Addition of Naltrexone to Methadone Taper treatment 2 completed NCT02922959
A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses prevention Not Available completed NCT00000259
Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11 Not Available Not Available completed NCT04325659
An Innovative Intervention for OUD Treatment treatment 2 / 3 recruiting NCT00134875
Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers treatment Not Available terminated NCT01530542
A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers basic_science 1 completed NCT00471042
Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care No drug interventions Not Available Not Available completed NCT04164342
Prevalence of Chronic Pain and Its Risk Factors After a Surgical Intensive Care Unit Stay. Prospective Observational Cohort No drug interventions other Not Available completed NCT03932799
Comparing State Payer Strategies to Prevent Unsafe Opioid Prescribing No drug interventions Not Available Not Available completed NCT04740099
Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) No drug interventions health_services_research Not Available withdrawn NCT03845699
Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose No drug interventions Not Available Not Available unknown_status NCT01275599
Drug-Drug Interaction Study Between Telaprevir and Buprenorphine treatment 1 completed NCT01570699
Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients No drug interventions Not Available Not Available completed NCT02282306
Phone Interview to Prevent Recurring Opioid Overdoses No drug interventions prevention Not Available completed NCT02660606
A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire No drug interventions Not Available Not Available completed NCT05657106
Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk No drug interventions prevention Not Available active_not_recruiting NCT06001749
Psilocybin in Cancer Pain Study treatment 2 not_yet_recruiting NCT02668549
Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction No drug interventions Not Available Not Available completed NCT00158236
Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users treatment Not Available completed NCT00000219
Buprenorphine Dose Alteration Study - 1 treatment 1 completed NCT02660619
Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication No drug interventions Not Available Not Available completed NCT00000319
Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2 treatment 2 completed NCT00000341
Evaluation of Liquid vs. Tablet Buprenorphine - 6 treatment 2 completed NCT02978417
Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings other 4 completed NCT03137017
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults treatment 1 withdrawn NCT00396734
The Effects of Pharmacotherapy on Brain Mechanisms Underlying Cocaine Dependence. No drug interventions treatment Not Available suspended NCT00000334
Comparison of Buprenorphine and Methadone - 3 treatment 2 completed NCT02247024
Pupil Response in Patients on Opioids. No drug interventions Not Available Not Available completed NCT05651516
Tau PET Imaging in Opioid Use Disorder No drug interventions diagnostic 0 recruiting NCT00142896
Tramadol to Reduce Opioid Withdrawal Symptoms treatment 2 completed NCT00124358
Buprenorphine and Integrated HIV Care Evaluation treatment 4 unknown_status NCT05859035
Informational App Development for mHealth for Patient Self-Management of Opioid Use Disorder No drug interventions other Not Available active_not_recruiting NCT00149539
Abuse Potential of Buprenorphine/Naloxone treatment 2 terminated NCT00000222
Alternate-Day Buprenorphine Administration. Phase II - 4 treatment 1 completed NCT02733822
Buccal Versus Injectable Naloxone: a Phase I Healthy Volunteer Study Not Available 1 unknown_status NCT00000225
Alternate-Day Buprenorphine Administration. Phase VI - 7 treatment 2 completed NCT01536925
Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects No drug interventions Not Available Not Available completed NCT03137030
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults treatment 1 withdrawn NCT00000230
Buprenorphine Detoxification With Two Types of Treatment. BBD III - 12 treatment 2 completed NCT00000357
Buprenorphine Maintenance for Opiate Dependence - 6 treatment 2 completed NCT03911466
Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study treatment 3 active_not_recruiting NCT02866266
ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning No drug interventions Not Available Not Available unknown_status NCT00000265
Subjective Effects of Nitrous Oxide in Dental Patients - 17 No drug interventions Not Available Not Available completed NCT01517165
Pioglitazone to Treat Opioid Withdrawal Symptoms treatment 1 terminated NCT00000220
Gradual Vs. Rapid Buprenorphine Detoxification - 2 treatment 1 completed NCT06134882
OUD Smartphone Services No drug interventions health_services_research Not Available recruiting NCT04235582
Incentives to Decrease Opioid Use - Pilot No drug interventions treatment Not Available completed NCT00000331
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6 No drug interventions treatment 2 withdrawn NCT00000231
Buprenorphine Detoxification With Two Types of Treatment. BBD IV - 13 treatment 2 completed NCT04495673
Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Opioid Use Disorder No drug interventions treatment Not Available completed NCT00000227
Alternate-Day Buprenorphine Administration. Phase VIII - 9 treatment 2 completed NCT03521960
Buspirone for Opioid Tapering treatment 1 completed NCT00000260
Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12 Not Available Not Available completed NCT00726960
Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers No drug interventions treatment 1 unknown_status NCT00000194
Neurobiology of Opioid Dependence: 3 - 3 treatment 2 withdrawn NCT02372591
Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain treatment 1 completed NCT03961789
Assessment of the Satisfaction of Patient Undergoing Opioid Replacement Therapy Toward Their Management in Community Pharmacy No drug interventions Not Available Not Available completed NCT02572089
Pharmacokinetic Evaluation of Intranasal and Intramuscular Naloxone in Healthy Volunteers No drug interventions treatment 1 completed NCT03950492
Feasibility of Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder No drug interventions other Not Available active_not_recruiting NCT00000192
Neurobiology of Opioid Dependence: 1 - 1 treatment 2 withdrawn NCT03678792
Comparison of Three Opioid Detoxification Treatment Regimens No drug interventions treatment 3 withdrawn NCT00684840
Effects of Stress and Other Factors on Opiate Drug Choice. No drug interventions Not Available Not Available completed NCT00218101
Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids treatment 2 completed NCT00000204
Buprenorphine Maintenance for Opioid Addicts - 3 treatment 2 completed NCT00608504
Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals. No drug interventions Not Available Not Available completed NCT03306368
Youth Opioid Recovery Support: A Developmentally-specific Intervention for Home Delivery of Extended Release Naltrexone No drug interventions treatment Not Available completed NCT00149669
Employment-based Reinforcement of Naltrexone Ingestion and Abstinence No drug interventions treatment Not Available completed NCT03698669
Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings No drug interventions treatment Not Available active_not_recruiting NCT01999946
Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry No drug interventions treatment 4 completed NCT02526212
Buprenorphine Group Medical Visits in Primary Care No drug interventions treatment 3 completed NCT02667210
Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review No drug interventions Not Available Not Available completed NCT03684681
The Navigator Trial No drug interventions treatment Not Available completed NCT05903495
Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder No drug interventions treatment Not Available recruiting NCT00000195
Neurobiology of Opioid Dependence: 4 - 4 treatment 2 withdrawn NCT02897414
ER/LA Opioid Analgesics - Surveillance Monitoring of State Medical Examiner Databases No drug interventions Not Available Not Available unknown_status NCT00134914
Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence treatment Not Available completed NCT00000255
Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7 treatment 2 completed NCT03143855
Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder No drug interventions treatment 1 completed NCT02616523
Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine Resection No drug interventions treatment 4 completed NCT05387408
Improving Health and Employment Outcomes Through Workplace Opioid Policies No drug interventions other Not Available unknown_status NCT00295308
Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients No drug interventions treatment 1 completed NCT04251208
MOms in REcovery (MORE) Study: Defining Optimal Care No drug interventions Not Available Not Available completed NCT02992938
Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia No drug interventions prevention 4 completed NCT00000238
Temporal Discounting Delayed Outcomes on Opioid-Dependent Outpatients - 20 treatment 2 completed NCT02583243
Project BEST: Buprenorphine Entry Into Substance Abuse Treatment No drug interventions Not Available Not Available completed NCT06454903
Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment No drug interventions treatment Not Available not_yet_recruiting NCT00000203
Buprenorphine Maintenance for Opioid Addicts - 2 treatment 2 completed NCT02797990
Conflict Between Maternal Autonomy and Child Health in Substance-use No drug interventions Not Available Not Available completed NCT06387290
Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits No drug interventions treatment Not Available not_yet_recruiting NCT03022890
Study of Yoga vs. Health Education for Chronic Pain in Persons Receiving Opioid Agonist Therapy No drug interventions treatment Not Available completed NCT03949764
The Kentucky Viral Hepatitis Treatment Study No drug interventions treatment 4 active_not_recruiting NCT03948464
Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder No drug interventions treatment 3 terminated NCT00000221
Alternate-Day Buprenorphine Administration. Phase I - 3 treatment 1 completed NCT06084221
Fatal Overdose Review Teams - Research to Enhance Surveillance Systems No drug interventions prevention Not Available enrolling_by_invitation NCT05603702
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis No drug interventions treatment 1 recruiting NCT00780702
Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients No drug interventions treatment 1 completed NCT00000202
Buprenorphine Maintenance for Opioid Addicts - 1 treatment 2 completed NCT00158184
Prescription Opioid Effects in Abusers Versus Non-Abusers basic_science 2 completed NCT00067184
Fetal Neurobehavioral Development in Methadone Maintained Pregnancies No drug interventions Not Available Not Available completed NCT01315184
Study of Computer-Based Treatment for Drug Dependence No drug interventions treatment 2 completed NCT02225184
Impact of Delta Opioid Receptor Gene (OPRD1) Variations on Treatment Outcome in African Americans No drug interventions Not Available Not Available completed NCT01108679
Neurocognitive Effects of Buprenorphine Among HIV+ and HIV-Opioid Users No drug interventions Not Available Not Available completed NCT00142779
Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts treatment Not Available completed NCT00061087
Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1 treatment 2 / 3 completed NCT00000233
Alternate Day Buprenorphine Administration, Phase X - 15 treatment 2 completed NCT00000254
Isoflurane at Subanesthetic Concentrations - 6 treatment 2 completed NCT00000251
Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3 treatment 2 completed NCT00316277
Prescription Opioid Addiction Treatment Study (POATS) No drug interventions treatment 3 completed NCT00723177
Phase IIa Study of AV411, a Glial Activation Inhibitor, for Opioid Withdrawal No drug interventions basic_science 2 completed NCT00000345
Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10 treatment 1 completed NCT01471145
Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT No drug interventions basic_science 4 completed NCT00000205
Buprenorphine Maintenance Protocol - 1 treatment 3 completed NCT05512897
Does ESP Block Reduce Pain and Opiates Consumption After Surgery No drug interventions treatment Not Available unknown_status NCT00023283
Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1 treatment 2 completed NCT00000261
Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13 Not Available 2 completed NCT00218361
Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals No drug interventions Not Available Not Available completed NCT00000228
Buprenorphine Detox With Two Types of Treatment. BBD I - 10 treatment 2 completed NCT00000328
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment III) - 3 No drug interventions treatment 2 withdrawn NCT04199728
Use of a GLP-1R Agonist to Treat Opioid Use Disorder No drug interventions treatment 1 / 2 completed NCT03394911
Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction No drug interventions treatment 3 unknown_status NCT00000311
Combining Behavioral Treatment With Agonist Maintenance - 1 treatment 3 completed NCT01004393
Methylnaltrexone for Opioid-induced Constipation in Cancer Patients No drug interventions supportive_care 2 completed NCT04272671
De-prescribing Program to Evaluate Falls in Older Adults No drug interventions prevention Not Available completed NCT03859778
Evaluation of Pharmacy Students' Perception of Opioid / Opiate Dependence No drug interventions Not Available Not Available completed NCT00015288
Buprenorphine and Naloxone Combination Study - 10 treatment 1 completed NCT04188288
Neurofeedback in Individuals With Substance Use Disorders No drug interventions treatment Not Available terminated NCT02678507
A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnaire No drug interventions Not Available Not Available completed NCT02360007
Interim Buprenorphine: Leveraging Medication + Technology to Bridge Delays in Treatment Access No drug interventions treatment 1 / 2 completed NCT00142909
Effectiveness of Lofexidine to Prevent Stress-Related Opiate Relapse During Naltrexone Treatment - 1 treatment 2 completed NCT02941809
Harnessing Placebo Effects in Methadone Treatment No drug interventions treatment Not Available completed NCT00000209
Buprenorphine Dosing Interval - 5 treatment 2 completed NCT05480956
SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs No drug interventions prevention Not Available recruiting NCT03567356
Treatment of Opioid Use: Medication Adherence Therapy No drug interventions treatment Not Available completed NCT00000256
Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8 Not Available Not Available completed NCT00710385
Abuse Liability of Suboxone Versus Subutex No drug interventions basic_science 3 completed NCT04015115
Youth Opioid Recovery Support: Improving Care Systems No drug interventions treatment Not Available completed NCT00000232
Alternate Day Buprenorphine Administration, Phase IX - 14 treatment 2 completed NCT02093559
Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients No drug interventions prevention Not Available completed NCT06023459
Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) No drug interventions treatment 3 not_yet_recruiting NCT00249470
The Therapeutic Workplace Initiation Study No drug interventions treatment Not Available completed NCT00032942
Lofexidine for Opiate Withdrawal - 1 treatment 3 completed NCT00000299
Rapid Opiate Detoxification and Naltrexone Induction Using Buprenorphine - 2 treatment 2 completed NCT00000206
Clinical Rescue Protocol - 2 treatment 2 completed NCT00000306
Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3 treatment 2 completed NCT00237406
Interactive Voice Response (IVR) for Methadone Patients No drug interventions Not Available Not Available completed NCT00723749
Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603) No drug interventions Not Available Not Available completed NCT00000249
Effects of Subanesthetic Concentrations of Nitrous Oxide - 1 treatment 2 completed NCT00000236
Buprenorphine Pharmacology Related to Addiction Treatment - 18 treatment 2 completed NCT00000318
Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1 treatment 2 completed NCT03804619
Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder No drug interventions treatment Not Available withdrawn NCT00015041
Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2 treatment 1 completed NCT00078117
Suboxone: (Buprenorphine/Naloxone) Comparison of Two Taper Schedules - 1 treatment 3 completed NCT00000234
Alternate Day Buprenorphine Administration, Phase XI - 16 treatment 2 completed NCT00000224
Alternate-Day Buprenorphine. Phase V - 6 treatment 1 completed NCT03427424
Imaging Biomarker for Addiction Treatment Outcome No drug interventions Not Available Not Available terminated NCT00000216
Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1 treatment 3 completed NCT02896296
Open-Label Treatment Extension Study No drug interventions treatment 3 completed NCT00000196
Neurobiology of Opioid Dependence: 5 - 5 treatment 2 withdrawn NCT05086796
Substance Use Treatment and Recovery Team No drug interventions treatment Not Available completed NCT02667158
A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or Diversion No drug interventions Not Available Not Available completed NCT00000358
Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 7 treatment 1 completed NCT00000258
Role of Instructions in Nitrous Oxide Effects and Choice - 10 No drug interventions Not Available Not Available completed NCT00142935
Effectiveness of Opiate Replacement Therapy Administered Prior to Release From a Correctional Facility - 1 No drug interventions prevention Not Available completed NCT00000335
Activity Monitoring Assessment of Opiate Withdrawal - 4 treatment 2 completed NCT00640835
Safety and Tolerability of Buprenorphine/Naloxone Film Strips No drug interventions treatment 2 completed NCT02902835
BUPrenorphine Facilitated Access and Supportive Treatment --AIM 3 No drug interventions treatment Not Available terminated NCT00000235
Alternate Day Buprenorphine Administration, Phase XII - 17 treatment 2 completed NCT06215963
A4i-O: A Platform for Complex Behavioral Health to Address OUD No drug interventions treatment Not Available recruiting NCT00000263
Effects of Combined Alcohol and Nitrous Oxide Intake - 15 Not Available Not Available completed NCT01880086
Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration No drug interventions treatment 2 completed NCT03316339
Postoperative and Opioid Free Anesthesia No drug interventions treatment 3 terminated NCT03911739
Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study No drug interventions treatment 3 recruiting NCT00460239
Buprenorphine's Dose Response Curve No drug interventions treatment 2 completed NCT00000239
Buprenorphine Pharmacology Related to Addiction Treatment - 21 treatment 2 completed NCT03745339
Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder No drug interventions Not Available Not Available recruiting NCT01344122
Medication-Assisted Treatment Implementation in Community Correctional Environments (MATICCE) No drug interventions Not Available Not Available completed NCT00078130
Buprenorphine/Naloxone - Facilitated Rehabilitation for Opioid Dependent Adolescents - 1 treatment 3 completed NCT00000330
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-2 - 5 No drug interventions treatment 2 withdrawn NCT02750748
Pharmacokinetic Evaluation of Intranasal, Intramuscular, and Oral Naltrexone in Healthy Volunteers No drug interventions treatment 1 completed NCT04314648
Substance Use Treatment and Recovery Team (START) No drug interventions treatment Not Available completed NCT00270257
Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users prevention 3 terminated NCT00000257
Effects of Alcohol History on Effects of Nitrous Oxide - 9 Not Available Not Available completed NCT00000226
Alternate-Day Buprenorphine Administration. Phase VII - 8 treatment 2 completed NCT00000326
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment 1 - 1 treatment 2 withdrawn NCT05577026
Safe Prescription of Opioids in Primary Care No drug interventions health_services_research Not Available active_not_recruiting NCT00218426
Addiction Treatment in Russia: Oral vs. Naltrexone Implant treatment 2 / 3 completed NCT00018226
Effect Of Case Management Following Discharge From Methadone Treatment No drug interventions treatment 2 completed NCT05141266
Healthy Opioid Prescription Engagement No drug interventions health_services_research Not Available recruiting NCT03411265
RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing No drug interventions prevention Not Available completed NCT00218374
Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia treatment Not Available completed NCT00000320
Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1 treatment 1 / 2 completed NCT06554431
Assessing the Efficacy of Self-Driven Repetitive Artmaking Practice No drug interventions health_services_research Not Available recruiting NCT00000273
A Laboratory Model for Heroin Abuse Medications - 8 treatment 2 completed NCT00142727
Opioid Agonist and Antagonist Effects on Opioid Dependence treatment 2 terminated NCT00218127
Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens treatment 2 completed NCT05505227
Developing a Tailored Stigma Reduction Intervention to Increase Buprenorphine Prescribing No drug interventions health_services_research Not Available recruiting NCT00000327
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment I(2) - 2 treatment 2 withdrawn NCT05122676
More Individualized Care: Assessment and Recovery Through Engagement No drug interventions treatment Not Available active_not_recruiting NCT05840276
Cryoneurolysis Prior to Total Knee Arthroplasty No drug interventions treatment Not Available recruiting NCT01909076
Transforming Opioid Prescribing in Primary Care No drug interventions prevention Not Available completed NCT02741076
Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain No drug interventions treatment 4 terminated NCT04961294
EA for Protracted Withdrawal of OUD No drug interventions treatment Not Available unknown_status NCT02667262
An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data No drug interventions Not Available Not Available completed NCT02751762
A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain No drug interventions Not Available Not Available unknown_status NCT00000262
Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14 treatment Not Available completed NCT03287180
Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use No drug interventions treatment Not Available withdrawn NCT03526380
The OPT-IN Project No drug interventions health_services_research Not Available completed NCT00000329
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4 No drug interventions treatment 2 withdrawn NCT00000229
Buprenorphine Detox With Two Types of Treatment. BBD II - 11 treatment 2 completed NCT00000244
Effects of Dynorphin 1-13 on Heroin Addiction - 1 treatment 2 completed NCT00000344
Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9 treatment 2 completed NCT04675840
Intrathecal Morphine for Robotic-assisted Laparoscopic Hysterectomy. No drug interventions treatment Not Available completed NCT05380440
Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: FAIR No drug interventions prevention Not Available active_not_recruiting NCT03175640
Prescribe to Save Lives No drug interventions health_services_research Not Available completed NCT00000240
Combined Buprenorphine and Behavioral Treatment With and Without Contingent Reinforcement on Opioid and Cocaine Abstinence. - 22 treatment 2 completed NCT00429767
Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals No drug interventions Not Available Not Available completed NCT01595867
Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo No drug interventions basic_science 1 completed NCT02669901
Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Use Disorder No drug interventions prevention Not Available completed NCT04320004
Evaluation of a Medication Disposal Program in Primary Care No drug interventions health_services_research Not Available completed NCT03610672
Mobile Intervention for Young Opioid Users No drug interventions treatment Not Available unknown_status NCT02969668
Interferon-free Antiviral Treatment of Chronic Hepatitis C Virus Infection Among Opioid-substituted Patients No drug interventions Not Available Not Available completed NCT00348868
Buprenorphine HIV Care Integration Project No drug interventions treatment Not Available completed NCT01759446
Abuse Potential of Intranasal VYCAVERT Tablets (Hydrocodone Bitartrate/Acetaminophen) in Recreational Opioid Users No drug interventions treatment 2 completed NCT00218010
Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2 No drug interventions Not Available Not Available completed NCT03925610
Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients No drug interventions Not Available Not Available terminated NCT03838510
Repeated-dose Behavioral Intervention to Reduce Opioid Overdose No drug interventions prevention Not Available completed NCT00301210
Assessment of Tramadol as a Treatment for Opioid Addiction No drug interventions treatment 1 / 2 completed NCT00992095
Bioequivalency Study of Buprenorphine Hydrochloride 8 mg Tablet Under Fasted Conditions No drug interventions treatment Not Available completed NCT03161795
Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain No drug interventions Not Available Not Available completed NCT02510014
Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder No drug interventions treatment 3 completed NCT03377855
Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients No drug interventions other Not Available completed NCT06543355
The Acupuncture for Pain, Opioid Use Disorder and Mood No drug interventions health_services_research Not Available not_yet_recruiting NCT00000355
Effects of Buprenorphine and Naloxone in Opiate Addicts - 4 treatment 1 completed NCT03918850
Medication Treatment for Opioid Use Disorder in Expectant Mothers No drug interventions treatment 3 active_not_recruiting NCT00000250
Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2 treatment 2 completed NCT00000223
Alternate-Day Buprenorphine Administration. Phase IV - 5 treatment 2 completed NCT00218608
Disulfiram for Treating Cocaine Dependence in Individuals Maintained on Methadone treatment 2 completed NCT00725608
Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444) No drug interventions Not Available Not Available completed NCT00000208
Methadone/Buprenorphine Cross-Over Study - 4 treatment 2 completed NCT03143543
Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder No drug interventions treatment 1 terminated