Hydrogen Sulfide

Name
Hydrogen Sulfide
Accession Number
DBCAT000319
Description

A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)

Drugs
DrugDrug Description
CystineAn oxidated derivative of the amino acid cysteine found in various nutritional products, acne treatments, and creams to treat cervical injury or inflammation.
MontelukastA leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
SteproninStrepronin is a mucolytic (expectorant) drug.
2-Hydroxyethyl DisulfideNot Available
PX-12Investigated for use/treatment in cancer/tumors (unspecified), gastric cancer, and pancreatic cancer.
4,4'-DIPYRIDYL DISULFIDENot Available
Sodium sulfideSodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes...
Calcium sulfideNot Annotated
PF-4191834PF-4191834 has been investigated for the basic science of Asthma.
AllicinAllicin has been used in trials studying the treatment of Follicular Lymphoma.
DevimistatDevimistat (CPI-613) has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others.
GW-274150GW274150 has been used in trials studying the treatment and prevention of Asthma, Migraine, Migraine Disorders, and Arthritis, Rheumatoid.
ImrecoxibImrecoxib has been used in trials studying the treatment of Knee Osteoarthritis.
QGC-001QGC001 has been used in trials studying the treatment of Essential Hypertension.
MesulfenNot Annotated
Antimony pentasulfideNot Annotated
DixanthogenNot Annotated
TAK-243TAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia).
DostarlimabAn anti-PD-1 monoclonal antibody used in the treatment of mismatch repair deficient endometrial cancers and solid tumours with no alternative treatment options.
Garlic oilNot Annotated
DarapladibInvestigated for use/treatment in atherosclerosis.
PF-03715455PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).
UmifenovirA dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses.
AjoeneNot Annotated
Tetradecylthioacetic acidNot Available
Tetraarsenic tetrasulfideTetraarsenic tetrasulfide is under investigation in clinical trial NCT05682131 (South China Children Cancer Group - Relapsed-acute Lymphoblastic Leukemia 2022 Protocol).
Drugs & Drug Targets
DrugTargetType
CystineCystine/glutamate transportertarget
CystineCystinosintarget
CystineMonocarboxylate transporter 10transporter
Cystineb(0,+)-type amino acid transporter 1transporter
CystineAmino acid transporter heavy chain SLC3A1transporter
MontelukastCysteinyl leukotriene receptor 1target
MontelukastPolyunsaturated fatty acid 5-lipoxygenasetarget
MontelukastCytochrome P450 3A4enzyme
MontelukastCytochrome P450 2C9enzyme
MontelukastCytochrome P450 2C8enzyme
MontelukastSolute carrier organic anion transporter family member 2B1transporter
MontelukastProstaglandin G/H synthase 1enzyme
MontelukastCytochrome P450 2A6enzyme
2-Hydroxyethyl DisulfideEndolysintarget
2-Hydroxyethyl DisulfideGlutathione S-transferase A1target
2-Hydroxyethyl DisulfideGlutathione S-transferase A1enzyme
PX-12Thioredoxin reductase 1, cytoplasmictarget
PX-12Thioredoxintarget
4,4'-DIPYRIDYL DISULFIDECytochrome P450 2A6target
PF-4191834Polyunsaturated fatty acid 5-lipoxygenasetarget
Devimistat2-oxoglutarate dehydrogenase complex component E1target
GW-274150Nitric oxide synthase, inducibletarget
ImrecoxibProstaglandin G/H synthase 1target
ImrecoxibProstaglandin G/H synthase 2target
QGC-001Glutamyl aminopeptidasetarget
QGC-001Aspartyl aminopeptidasetarget
DostarlimabProgrammed cell death protein 1target
DarapladibCytosolic phospholipase A2target
DarapladibPhospholipase A2target
UmifenovirUDP-glucuronosyltransferase 1A9enzyme
UmifenovirUDP-glucuronosyltransferase 2B7enzyme
UmifenovirCytochrome P450 3A4enzyme
UmifenovirCytochrome P450 2E1enzyme
UmifenovirCytochrome P450 1A2enzyme
UmifenovirCytochrome P450 2D6enzyme
UmifenovirCytochrome P450 2C9enzyme
UmifenovirCytochrome P450 3A5enzyme
UmifenovirFlavin-containing monooxygenase 3enzyme
UmifenovirFlavin-containing monooxygenase 1enzyme