Purinones
- Name
- Purinones
- Accession Number
- DBCAT000504
- Description
Cyclic compounds that include atoms other than carbon in their ring structure.
- Drugs
Drug Drug Description 3-isobutyl-1-methyl-7H-xanthine Not Available 5'-S-methyl-5'-thioadenosine Not Available 6-O-benzylguanine 6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others. 7-cyano-7-deazaguanine Not Available 7-Deazaguanine Not Available 7,9-Dimethylguanine Not Available 8-azaguanine 8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids. 8-azaxanthine Not Available 8-chlorotheophylline When used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness. 9-Deazaguanine Not Available 9-Deazahypoxanthine Not Available 9-Methylguanine Not Available Acefylline Not Annotated Acyclovir A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. Ambroxol acefyllinate A bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Bamifylline A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm. Besifovir Not Annotated Besifovir dipivoxil Investigated for use/treatment in hepatitis (viral, B). Bromotheophylline Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with... Bufylline Not Annotated Cafaminol Cafaminol is a small molecule drug. Cafaminol has a monoisotopic molecular weight of 267.13 Da. Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Caffeine A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. Cipamfylline Cipamfylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Cipamfylline is a N-methylated xanthine derivative. Cipamfylline has a monoisotopic molecular weight... CT-2584 CT-2584 has been used in trials studying the treatment of Prostate Cancer. Denbufylline Denbufylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Denbufylline is a N-methylated xanthine derivative. Denbufylline has a monoisotopic molecular weight... Desciclovir Desciclovir is a small molecule drug. The usage of the INN stem '-ciclovir' in the name indicates that Desciclovir is a antiviral, bicyclic heterocycle compound. Desciclovir has a monoisotopic molecular... Dezaguanine Dezaguanine is a small molecule drug. Dezaguanine has a monoisotopic molecular weight of 150.05 Da. Dimenhydrinate A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. Doxofylline A methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms. DPCPX CPX has been used in trials studying the treatment of Cystic Fibrosis. Dyphylline A theophylline derivative used to treat asthma, bronchospasm, and COPD. Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Entecavir A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases. Etamiphylline Not Annotated Fenethylline Not Available Flufylline Flufylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Flufylline is a N-methylated xanthine derivative. Flufylline has a monoisotopic molecular weight... Furafylline Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline. Ganciclovir A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. Guanine Not Available Hypoxanthine Hypoxanthine is a purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway. Isbufylline Isbufylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Isbufylline is a N-methylated xanthine derivative. Isbufylline has a monoisotopic molecular weight... Lisofylline Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus. Lobucavir Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. Lomifylline Not Annotated Naxifylline Investigated for use/treatment in congestive heart failure. Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. PCS-499 PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients). Peldesine Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections. Penciclovir A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. Pentifylline Not Annotated Pentoxifylline A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs. Propentofylline Investigated for use/treatment in alzheimer's disease. Proxyphylline Not Annotated Queuine Current and on-going research suggests queuine is a natural biochemical compound that can be found endogenously in the human body and plays an essential role in the generation of other... Reproterol A short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma. Rolofylline Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure. Stacofylline Stacofylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Stacofylline is a N-methylated xanthine derivative. Stacofylline has a monoisotopic molecular weight... Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. Tonapofylline Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure. Torbafylline Torbafylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Torbafylline is a N-methylated xanthine derivative. Torbafylline has a monoisotopic molecular weight... Uric acid At present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke. Valaciclovir An guanine nucleoside antiviral used to treat herpes exacerbations. Valganciclovir An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). Valomaciclovir Investigated for use/treatment in herpes zoster infections and viral infection. Valomaciclovir stearate Valomaciclovir stearate is under investigation in clinical trial NCT00831103 (A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster). Xanthine A drug used to manage uncomplicated liver dysfunction in combination with orotic acid. Xanthinol A vasodilatory niacin found in diet supplements. - Drugs & Drug Targets