Pruritus Ani

Also known as: Anal pruritus / Sore bottom / Perianal irritation / Perianal itching / Pruritus perineal

DrugDrug NameDrug Description
DB13906Aloe vera leafIndicated for use as a topical agent to soothe sensitive skin and to relieve symptoms of various skin conditions, including contact or atopic dermatitis, eczema, dermatitis and acne urticata, first-...
DB15679Aluminum subacetateA medication used to prevent infection and treat irritation around the rectum.
DB11105BenzalkoniumAn antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.
DB13909Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
DB13346BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
DB15886CarvaseptA medication used to treat hemorrhoids, anal fissures, and pruritus ani.
DB00527CinchocaineAn anesthetic used for local or regional anesthesia.
DB04815ClioquinolAn antifungal cream used to treat a variety of fungal infections.
DB13155EsculinAs medication, esculin is sometimes used as a vasoprotective agent. Esculin is also used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria),...
DB14539Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB11341IchthammolIchthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed...
DB00646NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
DB12532OxetacaineAn antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DrugDrug NameTargetType
DB13906Aloe vera leafFree radicalstarget
DB13909Bismuth subgallateSerum albumincarrier
DB13346BufexamacProstaglandin G/H synthase 1target
DB13346BufexamacProstaglandin G/H synthase 2target
DB13346BufexamacHistone deacetylase 6target
DB13346BufexamacHistone deacetylase 10target
DB00527CinchocaineSodium channel protein type 5 subunit alphatarget
DB00527CinchocaineSodium channel protein type 10 subunit alphatarget
DB13155EsculinGlutaminase kidney isoform, mitochondrialenzyme
DB13155EsculinAndrogen receptortarget
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateP-glycoprotein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB00646NystatinSolute carrier organic anion transporter family member 1B1transporter
DB00646NystatinSolute carrier organic anion transporter family member 1B3transporter
DB12532OxetacaineCytochrome P450 3A4enzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB00281LidocaineNot AvailableCompleted1