Gallamine
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Gallamine
- DrugBank Accession Number
- DB13584
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Gallamine (DB13584)
- Weight
- Average: 423.642
Monoisotopic: 423.346092321 - Chemical Formula
- C24H45N3O3
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software1,2-Benzodiazepine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Gallamine. Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Gallamine. Acetophenazine The risk or severity of adverse effects can be increased when Acetophenazine is combined with Gallamine. Acetyldigitoxin The risk or severity of Cardiac Arrhythmia can be increased when Gallamine is combined with Acetyldigitoxin. Aclidinium Gallamine may increase the central nervous system depressant (CNS depressant) activities of Aclidinium. Agomelatine The risk or severity of adverse effects can be increased when Agomelatine is combined with Gallamine. Alfentanil The risk or severity of adverse effects can be increased when Gallamine is combined with Alfentanil. Alimemazine The risk or severity of adverse effects can be increased when Alimemazine is combined with Gallamine. Alloin The therapeutic efficacy of Alloin can be decreased when used in combination with Gallamine. Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Gallamine. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Categories
- ATC Codes
- M03AC02 — Gallamine
- Drug Categories
- Amines
- Ammonium Compounds
- Anticholinergic Agents
- Central Nervous System Depressants
- Cholinergic Agents
- Muscle Relaxants
- Muscle Relaxants, Peripherally Acting Agents
- Musculo-Skeletal System
- Neuromuscular Agents
- Neuromuscular Blocking Agents
- Neuromuscular-Blocking Agents (Nondepolarizing)
- Neurotoxic agents
- Neurotransmitter Agents
- Nicotinic Antagonists
- Nitrogen Compounds
- Onium Compounds
- Peripheral Nervous System Agents
- Quaternary Ammonium Compounds
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Phenol ethers
- Sub Class
- Not Available
- Direct Parent
- Phenol ethers
- Alternative Parents
- Phenoxy compounds / Alkyl aryl ethers / Trialkylamines / Organopnictogen compounds / Hydrocarbon derivatives
- Substituents
- Alkyl aryl ether / Amine / Aromatic homomonocyclic compound / Ether / Hydrocarbon derivative / Monocyclic benzene moiety / Organic nitrogen compound / Organic oxygen compound / Organonitrogen compound / Organooxygen compound
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- tertiary amine (CHEBI:503442)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 1146X1WTNM
- CAS number
- 153-76-4
- InChI Key
- ICLWTJIMXVISSR-UHFFFAOYSA-N
- InChI
- InChI=1S/C24H45N3O3/c1-7-25(8-2)16-19-28-22-14-13-15-23(29-20-17-26(9-3)10-4)24(22)30-21-18-27(11-5)12-6/h13-15H,7-12,16-21H2,1-6H3
- IUPAC Name
- (2-{2,3-bis[2-(diethylamino)ethoxy]phenoxy}ethyl)diethylamine
- SMILES
- CCN(CC)CCOC1=CC=CC(OCCN(CC)CC)=C1OCCN(CC)CC
References
- General References
- Not Available
- External Links
- ChemSpider
- 60750
- 4638
- ChEBI
- 503442
- ZINC
- ZINC000005650070
- PharmGKB
- PA164745088
- Wikipedia
- Gallamine_triethiodide
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.134 mg/mL ALOGPS logP 4.55 ALOGPS logP 3.7 ChemAxon logS -3.5 ALOGPS pKa (Strongest Basic) 9.71 ChemAxon Physiological Charge 3 ChemAxon Hydrogen Acceptor Count 6 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 37.41 Å2 ChemAxon Rotatable Bond Count 18 ChemAxon Refractivity 128 m3·mol-1 ChemAxon Polarizability 51.53 Å3 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created on June 23, 2017 20:44 / Updated on June 12, 2020 16:53