WHIM Syndrome

Also known as: Warts, hypogammaglobulinemia, infections, and myelokathexis (disorder) / Combined immunodeficiency, unspecified / Combined immunodeficiency / Combined immunodeficiency syndrome / Combined immunity deficiency / Combined immunodeficiencies / Combined immunodeficiency disease (disorder)

Drug	Drug Name	Drug Description
DB05501	Mavorixafor	A CXC chemokine receptor 4 antagonist used to treat WHIM syndrome.

Drug	Drug Name	Target	Type
DB05501	Mavorixafor	C-X-C chemokine receptor type 4	target
DB05501	Mavorixafor	Cytochrome P450 3A4	enzyme
DB05501	Mavorixafor	Cytochrome P450 2D6	enzyme
DB05501	Mavorixafor	Cytochrome P450 3A5	enzyme
DB05501	Mavorixafor	Cytochrome P450 2C19	enzyme
DB05501	Mavorixafor	Cytochrome P450 2B6	enzyme
DB05501	Mavorixafor	Cytochrome P450 1A2	enzyme
DB05501	Mavorixafor	Cytochrome P450 2C8	enzyme
DB05501	Mavorixafor	Cytochrome P450 2C9	enzyme
DB05501	Mavorixafor	P-glycoprotein 1	transporter
DB05501	Mavorixafor	Solute carrier family 22 member 2	transporter
DB05501	Mavorixafor	Multidrug and toxin extrusion protein 1	transporter

Drug	Drug Name	Phase	Status	Count
DB05501	Mavorixafor	2	Completed	1
DB05501	Mavorixafor	3	Active Not Recruiting	1