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Substrate
Enzyme
Products
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O-Desmethylverapamil (D-702)
DBMET00619
Cytochrome P450 3A5
/
Cytochrome P450 3A4
Verapamil metabolite D-620
Details
Odanacatib
DB06670
Cytochrome P450 3A4
/
Cytochrome P450 2C8
M8 (Odanacatib)
Details
Odanacatib
DB06670
Not Available
M6 (Odanacatib)
Details
Odanacatib
DB06670
Not Available
M9 (Odanacatib)
Details
Odanacatib
DB06670
Not Available
M10 (Odanacatib)
Details
Olanzapine
DB00334
Cytochrome P450 1A2
7-hydroxyolanzapine
Details
Olanzapine
DB00334
Cytochrome P450 1A2
4'-N-desmethylolanzapine
Details
Olanzapine
DB00334
Dimethylaniline monooxygenase [N-oxide-forming] 3
N-oxide olanzapine
Details
Olanzapine
DB00334
Cytochrome P450 2D6
2-hydroxymethylolanzapine
Details
Olanzapine
DB00334
Cytochrome P450 1A2
Olanzapine 10-N-glucuronide
Details
Olaparib
DB09074
Not Available
Olaparib M1 metabolite
Details
Olaparib
DB09074
Not Available
Olaparib M10 metabolite
Details
Olaparib M10 metabolite
DBMET03440
Cytochrome P450 3A4
/
Cytochrome P450 3A5
Olaparib M12 metabolite
Details
Oliceridine
DB14881
Not Available
Oxy-oliceridine
Details
Oliceridine
DB14881
Not Available
TRV0109662
Details
Olodaterol
DB09080
Cytochrome P450 2C9
/
Cytochrome P450 2C8
O-demethylated olodaterol
Details
Olopatadine
DB00768
Dimethylaniline monooxygenase [N-oxide-forming] 1
/
Dimethylaniline monooxygenase [N-oxide-forming] 3
Olopatadine N-oxide
Details
Olopatadine
DB00768
Cytochrome P450 3A4
N-desmethyl olopatadine
Details
Olsalazine
DB01250
Not Available
Mesalazine
Details
Olsalazine
DB01250
Not Available
Olsalazine-O-sulfate
Details
Omeprazole
DB00338
Cytochrome P450 2C9
/
Cytochrome P450 2C19
/
Cytochrome P450 3A4
5-Hydroxyomeprazole
Details
Omeprazole
DB00338
Cytochrome P450 2C19
5'-O-Desmethyl omeprazole
Details
Omeprazole
DB00338
Cytochrome P450 3A4
3-Hydroxyomeprazole
Details
Omeprazole
DB00338
Cytochrome P450 3A4
Omeprazole sulfone
Details
Omidenepag isopropyl
DB15071
Carboxylesterase
Omidenepag
Details
Ondansetron
DB00904
Cytochrome P450 3A4
/
Cytochrome P450 2D6
/
Cytochrome P450 1A2
6-OH-ondansetron
Details
Ondansetron
DB00904
Cytochrome P450 1A2
/
Cytochrome P450 2D6
/
Cytochrome P450 3A4
7-OH-ondansetron
Details
Ondansetron
DB00904
Cytochrome P450 1A2
/
Cytochrome P450 2D6
/
Cytochrome P450 3A4
8-OH-ondansetron
Details
Opicapone
DB11632
Not Available
BIA 9-1103
Details
Opicapone
DB11632
Not Available
BIA 9-1104
Details
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