Search

Displaying results 181 - 190 of 144451 in total
  1. Drug

    Selenium Sulfide

    go.drugbank.com/drugs/DB00971
    Approved

    Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. … Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent

    Mixtures: Clease and TreatProducts: Head and Shoulders Itch, Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff
  2. Pathway

    Valine, Leucine, and Isoleucine Degradation

    smpdb.ca/view/SMP0000032
    Metabolic

    and acetyl-CoA) and glucose (succinyl-CoA). … Leucine is ultimately converted into acetyl-CoA and acetoacetate; isoleucine into acetyl-CoA and succinyl-CoA; and valine into propionyl-CoA (and subsequently succinyl-CoA).

    Drugs: Pyridoxal phosphate · Biotin · Succinic acid · Glutamic acid · Pyridoxal · Leucine +10 more
  3. Pathway

    Threonine and 2-Oxobutanoate Degradation

    smpdb.ca/view/SMP0000452
    Metabolic

    2-oxobutanoate, also known as 2-Ketobutyric acid, is a 2-keto acid that is commonly produced in the metabolism of amino acids such as methionine and threonine. … E1 binds the 2-oxobutanoate to the lipoate on E2, which then transfers the propionyl group to coenzyme A, producing propionyl-CoA and reducing the lipoate.

    Drugs: Pyridoxal phosphate · Biotin · Threonine · NADH · ATP · Flavin adenine dinucleotide +1 more
  4. Drug

    Colloidal oatmeal

    go.drugbank.com/drugs/DB11286
    ApprovedInvestigationalNutraceutical

    Colloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. … It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties.

    Mixtures: Dermavive Shower and Bath OilProducts: JOSIE MARAN OTC ECZEMA BODY BUTTER -Vanilla and Chamomile, Aveeno Eczema Therapy Hand and Face
  5. Drug

    Levomenthol

    go.drugbank.com/drugs/DB00825
    ApprovedInvestigational

    Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration … Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used to relieve minor throat irritations.

    Mixtures: Neo Medicated Plaster with Ginger and Lemongrass Oil Aroma, Jack and Jill RubCategories: Basic Lotions and Liniments, Antipruritics and Local Anesthetics
  6. Pathway

    Apoptotic DNA Fragmentation and Tissue Homeostasis

    smpdb.ca/view/SMP0063772
    Signaling

    ICAD and CAD exist in the nucleus in normal cells and is a major endonuclease in apoptosis. Its activation is normally caspase dependent. … EndoG resides in mitochondria in normal cells and travels to the nucleus, where it fragments chromosomal DNA upon activation of apoptosis.

    Drugs: Zinc
  7. Pathway

    Metabolism and Physiological Effects of Creatinine

    smpdb.ca/view/SMP0123283
    Metabolic

    If not cleared, it can reduce cardiomyocyte contractility and weaken cardiac efficiency, leading to systolic dysfunction and heart failure. … Arginine from the diet is absorbed into systemic circulation and enters hepatocytes through an amino acid transporter, where it undergoes a series of metabolic reactions.

    Drugs: Ademetionine · Arginine · Ornithine · Glycine · Creatine · Glycocyamine
  8. Pathway

    Metabolism and Physiological Effects of Xanthine

    smpdb.ca/view/SMP0124865
    Metabolic

    The purines are guanine and adenine. These undergo metabolism in the liver to form xanthine. Adenine forms adenosine through the enzyme purine nucleoside phosphorylase. … Adenosine then reacts with water to form inosine and ammonia using the enzyme adenosine deaminase. Inosine goes on to form hypoxanthine through the enzyme purine nucleoside phosphorylase.

    Drugs: Adenine · Adenosine · Zinc · Xanthine · Guanine · Ribose-1-Phosphate +3 more
  9. Pathway

    Metabolism and Physiological Effects of Kynurenine

    smpdb.ca/view/SMP0125524
    Disease

    In the blood it travels to the liver and is transported into a hepatocyte by an amino acid transporter. … Kynurenine is shown to activate aryl hydrocarbon receptors that can lead to renal impairment, apoptosis, and kynurenine has also been found to disrupt the electron transport chain and oxidative phosphorylation

    Drugs: Tryptophan · Formic acid · Kynurenine · Mesoheme
    Enzymes: Neutral and basic amino acid transport protein rBAT
  10. Pathway

    Metabolism and Physiological Effects of Isovalerylglycine

    smpdb.ca/view/SMP0126748
    Metabolic

    its isomer, pivaloylcarnitine; pivaloylcarnitine is derived from pivalate-generating antibiotics, and has caused many false-positive results. … important to caution for false positive results when screening for isovaleric acidemia by tandem mass spectrometry based on dried blood-spot levels of C5-acylcarnitines, including isovalerylcarnitine and

    Drugs: Glycine · Proline