Search
Fenoprofen Action Pathway
smpdb.ca/view/SMP0000696Drug actionFenoprofen (also named Nalfon) is a nonsteroidal anti-inflammatory drug. Fenoprofen can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arac...
Phenylbutazone Action Pathway
smpdb.ca/view/SMP0000701Drug actionPhenylbutazone (also named fenilbutazona or butazolidin or bute) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat the pain and fever in animal. However, Phenylbutazone is not approved in United State and United K...
Drugs: Glutamic acid · Glutathione · Phenylbutazone · Dinoprostone · Calcium · Magnesium cation +5 moreTolmetin Action Pathway
smpdb.ca/view/SMP0000704Drug actionTolmetin (also named Tolectin) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to reduce pain, swelling, tenderness, and stiffness. Tolmetin can block prostaglandin synthesis by the action of inhibition of prostaglandin ...
Tiaprofenic Acid Action Pathway
smpdb.ca/view/SMP0000705Drug actionTiaprofenic Acid (also named tiaprofensaeure and surgam) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat pain (especially arthritic pain). Tiaprofenic can block prostaglandin synthesis by the action of inhibitio...
Salsalate Action Pathway
smpdb.ca/view/SMP0000707Drug actionSalsalate (also named Salflex, Disalcid or Salsitab) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat pain, fever and inflammation. Salsalate can block prostaglandin synthesis by the action of inhibition of prost...
Salicylate-Sodium Action Pathway
smpdb.ca/view/SMP0000708Drug actionSalicylate-sodium (also named salsonin or clin) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used for relieving pain and reducing fever. Salicylate-sodium can block prostaglandin synthesis by the action of inhibition of pr...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Salicylic acid +5 more2-Aminoadipic 2-Oxoadipic Aciduria
smpdb.ca/view/SMP0000719Disease2-Aminoadipic 2-oxoadipic aciduria is a disorder of lysine metabolism caused by a defective DHTKD1 gene. DHTKD1 is predicted to code for a component of a supercomplex similar to the 2-oxoglutarate dehydrogenase complex (OGDHc) which cata...
Drugs: Pyridoxal phosphate · Lysine · Glutamic acid · NADH · Oxogluric acid · Flavin adenine dinucleotide +1 moreCystinosis, Ocular Nonnephropathic
smpdb.ca/view/SMP0000722DiseaseOcular non-nephropathic cystinosis, also known as adult-onset cystinosis, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of the cysteine metabolism pathway. It is caused by a defect in the CTNS gene, which en...
Drugs: Pyridoxal phosphate · Pyruvic acid · Adenosine phosphate · Glutamic acid · Cysteine · NADH +6 moreFolate Malabsorption, Hereditary
smpdb.ca/view/SMP0000724DiseaseHereditary folate malabsorption, also known as folic acid transport defect, is an extremely rare inborn error of metabolism (IEM) and autosomal recessive disorder of the folate metabolism pathway. It is caused by a defect in the SLC46A1 ...
The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria
smpdb.ca/view/SMP0002358DiseaseHydroxyglutaric aciduria is a rare genetic disorder. Both isoforms are believed to have autosomal recessive inheritance. The compound 2-hydroxyglutarate is the product of gain-of-function mutations producing mutIDH1 and mutIDH2 in the cy...