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Displaying results 41 - 50 of 1911 in total
  1. Pathway

    Congenital Bile Acid Synthesis Defect Type III

    smpdb.ca/view/SMP0000318
    Disease

    Congenital Bile Acid Synthesis Defect Type III (CBASIII) is caused by a defect in 25-hydroxycholesterol 7-alpha-hydroxylase, which plays a role in synthesis of bile acids. … The synthesis of primary bile acids from cholesterol occurs via two pathways: the classic neutral pathway involving cholesterol 7-alpha-hydroxylase (CYP7A1), and the acidic pathway involving a distinct

    Drugs: Glycine · NADH · ATP · Iron · Taurine · Mesoheme +9 more
  2. Pathway

    Congenital Bile Acid Synthesis Defect Type II

    smpdb.ca/view/SMP0125689
    Disease

    Chenodeoxycholic acid and cholic acid are decreased in plasma and urine. … Congenital Bile Acid Synthesis Defect Type II is a congenital defect in bile acid synthesis with delta(4)-3-oxosteroid 5-beta-reductase deficiency is caused by mutation in the AKR1D1 gene. 3-oxo-5-beta-steroid

    Drugs: Glycine · NADH · ATP · Iron · Taurine · Mesoheme +9 more
  3. Indication

    Folic Acid Deficiency Anemia

    go.drugbank.com/conditions/DBCOND0127403
    Drugs: Ferrous sulfate anhydrous · Folic acid · Leucovorin · Thiamine
    Synonyms: Folic Acid Deficiency Anemia, Anemia folic acid deficiency
  4. Indication

    Folic acid antagonist overdose

    go.drugbank.com/conditions/DBCOND0024088
    Drugs: Ferrous fumarate · Leucovorin · Levoleucovorin
    Synonyms: Folic Acid Deficiency, Deficiency of folic acid
  5. Indication

    Folate deficiency

    go.drugbank.com/conditions/DBCOND0015758
    Drugs: (6R)-Folinic acid · Ascorbic acid · Calcium citrate · Cyanocobalamin · Ferrous gluconate · Ferrous sulfate anhydrous +4 more
    Synonyms: Folic acid deficiency, Deficiency of folic acid
  6. Drug

    Gastric intrinsic factor

    go.drugbank.com/drugs/DB09349
    Approved

    However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias

    Mixtures: Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic AcidCategories: Amino Acids, Peptides, and Proteins
  7. Indication

    Pellagra

    go.drugbank.com/conditions/DBCOND0004063
    Drugs: Niacin
    Synonyms: Nicotinic acid deficiency
  8. Drug

    Calcium threonate

    go.drugbank.com/drugs/DB11168
    ApprovedWithdrawn

    The most common form is calcium L-threonate, or (2R,3S)-2,3,4-trihydroxy butyric acid calcium [A27266]. … Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement [A27266].

    Mixtures: Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate and Succinic Acid, Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate and Succinic AcidCategories: Fatty Acids, Acids, Acyclic
  9. Pathway

    Oxidation of Branched-Chain Fatty Acids

    smpdb.ca/view/SMP0000030
    Metabolic

    Unfortunately, traditional fatty acid oxidation does not work for branched-chain fatty acids, or fatty acids that do not have an even number of carbons, like the fatty acid phytanic acid, found in animal … In the majority of organisms, fatty acid degradation occurs mostly through the beta-oxidation cycle.

    Drugs: Ascorbic acid · Succinic acid · ATP · Levocarnitine · Magnesium cation · Iron +2 more
    Enzymes: Long-chain-fatty-acid--CoA ligase 1
  10. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a rati...

    Mixtures: Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid