Search
Tiaprofenic Acid Action Pathway
smpdb.ca/view/SMP0000705Drug actionTiaprofenic Acid (also named tiaprofensaeure and surgam) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat pain (especially arthritic pain). … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Mycophenolic Acid Action Pathway
smpdb.ca/view/SMP0122722Drug actionIt inhibits the purine de novo synthesis for purine nucleotides through inhibiting the enzyme inosine 5'-monophosphate dehydrogenase which catalyzes the conversion of inosinic acid into xanthylic acid. … Mycophenolic acid is a selective, reversible and potent inhibitor of the enzyme.
Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +14 moreMeclofenamic acid Action Pathway
smpdb.ca/view/SMP0126104Drug actionMeclofenamic acid is administered as an oral capsule. … The cyclooxygenase pathway begins in the cytosol with phospholipids being converted into arachidonic acid by the action of phospholipase A2.
Drugs: Glutathione · Dinoprostone · Meclofenamic acid · Calcium · Mesoheme · Prostaglandin G2 +1 moreAcetylsalicylic Acid Action Pathway
smpdb.ca/view/SMP0000083Drug actionCOX-1 and -2 catalyze the conversion of arachidonic acid to prostaglandin G2 and prostaglandin G2 to prostaglandin H2. … Acetylsalicylic acid, also known as ASA or aspirin, belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs).
Drugs: Glutamic acid · Glutathione · Dinoprostone · Acetylsalicylic acid · Calcium · Magnesium cation +5 moreLysophosphatidic Acid LPA5 Signalling
smpdb.ca/view/SMP0063757SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 5Clorazepic Acid Action Pathway
smpdb.ca/view/SMP0126122Drug actionClorazepic acid or clorazepate is a benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal. … Some side effects of using clorazepic acid may include dizziness, nervousness, blurred vision, and headache.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Clorazepic acid · Calcium · Magnesium cation +4 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Phytanic Acid Peroxisomal Oxidation
smpdb.ca/view/SMP0000450MetabolicPhytanic acid, a branched chain fatty acid, is an important component of fatty acid intake, occuring in meat, fish and dairy products. … Pristanic acid then undergoes further metabolism through beta oxidation.
Salicylic Acid Action Pathway
smpdb.ca/view/SMP0000709Drug actionSalicylic acid (also named rutranex or salonil) is a nonsteroidal anti-inflammatory drug. Salicylic acid is also an important active metabolite of aspirin (acetylsalicylic acid). … Decreased prostaglandin synthesis in many animal model's cell is caused by presence of Salicylic acid.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Salicylic acid · Calcium · Magnesium cation +5 moreMethylphosphinic Acid Action Pathway
smpdb.ca/view/SMP0126733Drug actionMethylphosphinic acid is an experimental drug being tested to be a possible cholinesterase inhibitor, as it appears to inhibit the breakdown of acetylcholine.
3-Hydroxyisobutyric Acid Dehydrogenase Deficiency
smpdb.ca/view/SMP0125673Diseaseacid. … acid excreted in the urine.
Enzymes: Branched-chain-amino-acid aminotransferase, cytosolic, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial