| Aminopyrimidine aminohydrolase | Bacillus subtilis (strain 168) | Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reacti... more | 2 | Details |
| Aminotransferase | Thermus thermophilus | Not Available | 2 | Details |
| Aminotransferase, putative | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | Not Available | 1 | Details |
| Ammonium transporter AmtB | Escherichia coli (strain K12) | Involved in the uptake of ammonium/ammonia (NH(4)(+)/NH(3)). Transport is electrogenic. Following sequestration of NH... more | 3 | Details |
| Ammonium transporter Rh type B | Humans | Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related deriva... more | 1 | Details |
| Ammonium transporter Rh type C | Humans | Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related deriva... more | 2 | Details |
| Amorphous calcium phosphate | Humans | Not Available | 1 | Details |
| AMP deaminase 1 | Humans | AMP deaminase plays a critical role in energy metabolism | 2 | Details |
| AMP nucleosidase | Escherichia coli (strain K12) | Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulati... more | 1 | Details |
| Amphiregulin | Humans | Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells inclu... more | 1 | Details |
| Amyloid beta precursor like protein 1 | Humans | May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcr... more | 5 | Details |
| Amyloid beta precursor like protein 2 | Humans | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation ... more | 4 | Details |
| Amyloid-beta precursor protein | Humans | Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neuri... more | 51 | Details |
| Amylosucrase | Neisseria polysaccharea | Catalyzes the synthesis of alpha-glucan from sucrose. Catalyzes, in addition, sucrose hydrolysis, maltose and maltotr... more | 4 | Details |
| Anaerobic bacterial DNA | Not Available | This group represents the DNA of various anaerobic bacteria as a drug target. | 1 | Details |
| Anaerobic ribonucleoside-triphosphate reductase | Enterobacteria phage T4 | Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. | 4 | Details |
| Anamorsin | Humans | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extrami... more | 1 | Details |
| Anamorsin homolog | Plasmodium falciparum (isolate 3D7) | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extram... more | 1 | Details |
| Androgen receptor | Humans | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and aff... more | 148 | Details |
| Angiogenin | Humans | Secreted ribonuclease that can either promote or restrict cell proliferation of target cells, depending on the contex... more | 2 | Details |
| Angiopoietin-1 | Humans | Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important r... more | 1 | Details |
| Angiopoietin-1 receptor | Humans | Tyrosine-protein kinase that acts as a cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis... more | 15 | Details |
| Angiopoietin-2 | Humans | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosph... more | 7 | Details |
| Angiopoietin-related protein 3 | Humans | Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role ... more | 1 | Details |
| Angiotensin-converting enzyme | Humans | Dipeptidyl carboxypeptidase that removes dipeptides from the C-terminus of a variety of circulating hormones, such as... more | 58 | Details |