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Displaying targets 576 - 600 of 6103 in total
TargetOrganismDescription# of Drugs
Angiotensin-converting enzyme 2HumansEssential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of...  more12Details
AngiotensinogenHumansEssential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and elect...  more6Details
Ankyrin repeat and protein kinase domain-containing protein 1HumansNot Available1Details
Annexin A1HumansPlays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of...  more19Details
Annexin A2HumansCalcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. I...  more4Details
Annexin A3HumansInhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2...  more3Details
Annexin A4HumansCalcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis2Details
Annexin A5HumansThis protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, w...  more10Details
Annexin A6HumansMay associate with CD21. May regulate the release of Ca(2+) from intracellular stores1Details
Anoctamin-1HumansCalcium-activated chloride channel (CaCC). Plays a role in transepithelial anion transport and smooth muscle contract...  more9Details
Anthranilate phosphoribosyltransferaseErwinia carotovoraCatalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yi...  more1Details
Anthrax toxin receptor 1HumansPlays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytosk...  more1Details
Anthrax toxin receptor 2HumansNecessary for cellular interactions with laminin and the extracellular matrix1Details
Anti-Muellerian hormone type-2 receptorHumansOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine k...  more2Details
Anti-sigma F factor antagonistLysinibacillus sphaericusIn the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma...  more1Details
Antigen peptide transporter 1HumansABC transporter associated with antigen processing. In complex with TAP2 mediates unidirectional translocation of pep...  more1Details
Antigen-presenting glycoprotein CD1dHumansAntigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural ...  more3Details
Antithrombin-IIIHumansMost important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thro...  more20Details
Antitumor antibiotic C-1027 apoproteinStreptomyces globisporusBinds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromopho...  more1Details
Antiviral innate immune response receptor RIG-IHumansInnate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leadi...  more2Details
Antizyme inhibitor 2HumansAntizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptak...  more3Details
AP2-associated protein kinase 1HumansRegulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP...  more3Details
Apelin receptorHumansG protein-coupled receptor for peptide hormones apelin (APLN) and apelin receptor early endogenous ligand (APELA/ELA)...  more2Details
Apocarotenoid-15,15'-oxygenaseSynechocystis sp. (strain PCC 6803 / Kazusa)Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing reti...  more2Details
Apolipoprotein A-IHumansParticipates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol...  more11Details
Displaying targets 576 - 600 of 6103 in total