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Displaying targets 626 - 650 of 6103 in total
TargetOrganismDescription# of Drugs
Aquaporin-8HumansChannel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the ne...  more2Details
Aquaporin-9HumansAquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and ...  more7Details
Arabinose operon regulatory proteinEscherichia coli (strain K12)Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-ara...  more2Details
Arachidonate 12-lipoxygenase, 12R-typeHumansCatalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyu...  more1Details
Arachidonate 5-lipoxygenase-activating proteinHumansRequired for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic aci...  more6Details
Aralkylamine dehydrogenase heavy chainAlcaligenes faecalisOxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamin...  more4Details
Aralkylamine dehydrogenase light chainAlcaligenes faecalisOxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamin...  more4Details
ArginaseBacillus caldoveloxControls arginine catabolism.2Details
Arginase-1HumansCatalyzes the final step of the urea cycle by hydrolyzing L-arginine into urea, a nitrogenous waste product, and L-or...  more16Details
Arginase-2, mitochondrialHumansMay play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide...  more4Details
ArginineNot AvailableNot Available3Details
Arginine deiminasePseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Not Available1Details
Arginine N-succinyltransferase subunit alphaPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. Also acts on L-ornithine.1Details
Arginine/agmatine antiporterEscherichia coli O157:H7Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in th...  more1Details
Argininosuccinate lyaseHumansCatalyzes the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in...  more3Details
Argininosuccinate synthaseHumansOne of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabo...  more4Details
Argininosuccinate synthaseThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Not Available2Details
AromataseHumansA cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstened...  more75Details
Aromatic hydrocarbon degradation proteinRalstonia pickettiiNot Available1Details
Aromatic-amino-acid aminotransferaseParacoccus denitrificansShows activities toward both dicarboxylic and aromatic substrates.11Details
Aromatic-L-amino-acid decarboxylaseHumansCatalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin16Details
Arsenate reductaseEscherichia coliInvolved in resistance to arsenate. Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. The resulting ...  more5Details
Arsenate reductaseStaphylococcus aureusCatalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. In vitro, has also low phosphatase activity with p...  more3Details
ArsenicHumansNot Available3Details
Arsenical pump-driving ATPaseEscherichia coliAnion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of...  more4Details
Displaying targets 626 - 650 of 6103 in total