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Displaying targets 601 - 625 of 6103 in total
TargetOrganismDescription# of Drugs
Apolipoprotein A-IIHumansMay stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism3Details
Apolipoprotein A-IVHumansMay have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein l...  more3Details
Apolipoprotein B receptorHumansMacrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) ...  more8Details
Apolipoprotein B-100HumansApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo...  more6Details
Apolipoprotein C-IIHumansComponent of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lip...  more1Details
Apolipoprotein C-IIIHumansComponent of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Pl...  more4Details
Apolipoprotein DHumansAPOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the t...  more2Details
Apolipoprotein EHumansAPOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated ...  more9Details
Apolipoprotein L1HumansMay play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport...  more5Details
Apolipoprotein MHumansProbably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid...  more1Details
Apolipoprotein(a)HumansApo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteo...  more4Details
ApolipoproteinsHumansNot Available5Details
Apoptosis regulator BAXHumansPlays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant r...  more2Details
Apoptosis regulator Bcl-2RatSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Re...  more2Details
Apoptosis regulator Bcl-2HumansSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Re...  more31Details
Apoptosis regulatory protein SivaHumansInduces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-...  more4Details
Apoptosis-inducing factor 1, mitochondrialHumansFunctions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released...  more2Details
Apoptotic protease-activating factor 1HumansOligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to ...  more2Details
AppA proteinRhodobacter sphaeroidesNot Available1Details
Aquaporin ZEscherichia coli (strain K12)Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation an...  more4Details
Aquaporin ZShigella flexneriChannel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation an...  more1Details
Aquaporin-1HumansForms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water ...  more6Details
Aquaporin-10HumansAquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and ...  more2Details
Aquaporin-3HumansAquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and ...  more6Details
Aquaporin-7HumansAquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and ...  more4Details
Displaying targets 601 - 625 of 6103 in total