Displaying drugs 3051 - 3075 of 12063 in total
Rosin
Rosin is a solid form of resin obtained from pines and other plants, mostly conifers. It is prepared from heating fresh liquid resin to vaporize the volatile liquid terpene components. Rosin is used in various commercial and industrial applications, including printing, lead-tin industry, and food production. In the pharmaceuticals, rosin...
Approved
Matched Description: … Rosin is a solid form of resin obtained from pines and other plants, mostly conifers. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Primaquine
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Description: … malarias following treatment with a blood schizontocide. ... An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale ... been used to prevent transmission of falciparum malaria by those returning to areas where there is a …
Pazopanib
Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.
Approved
Matched Description: … Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Tolvaptan
Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Approved
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Pegloticase
Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … [L42425] Pegloticase was approved by the FDA in 2014, and in 2022, the drug label included the co-administration ... [L42425]
Pegloticase has a longer terminal elimination half-life thanks to the addition of a polyethylene ... Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polysorbate 20
Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer in labratory assays and industrial applications....
Approved
Matched Description: … Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical ... Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Poloxamer 188
Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a hydrophobic center core , its average molecular weight is 8400 Daltons. P188 was originally approved by the FDA in...
Approved
Investigational
Matched Description: … P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the ... The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety ... Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sodium bicarbonate
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte …
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Ethinamate
Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. Nevertheless, the medication itself is generally no longer effective after using it for greater than 7 days. Structurally, it...
Approved
Illicit
Withdrawn
Matched Description: … Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. ... similar medications, the regular use of ethinamate can result in the development of drug tolerance in a …
Copper oxodotreotide Cu-64
Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET). Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron...
Approved
Matched Description: … [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several ... times a day, and lower positron energy lending to improved spatial resolution. ... Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over …
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... antigens of *Streptococcus pneumoniae* serotype 11A individually conjugated to the CRM197 protein, a …
Calaspargase pegol
Asparaginase is an important agent used to treat acute lymphoblastic leukemia (ALL) . Asparagine is incorporated into most proteins, and the synthesis of proteins is stopped when asparagine is absent, which inhibits RNA and DNA synthesis, resulting in a halt in cellular proliferation. This forms the basis of asparaginase treatment...
Approved
Matched Description: … part of a multi-agent chemotherapy regimen for the treatment of ALL [L4890]. ... of proteins is stopped when asparagine is absent, which inhibits RNA and DNA synthesis, resulting in a ... Calaspargase pegol, also known as _asparlas_, is an asparagine specific enzyme which is indicated as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Pork collagen
Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic, full-thickness cartilage defects of the knee with or without bone involvement in adults. It serves as an alternative repair treatment for patients...
Approved
Investigational
Matched Description: … The surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Iupac: … 3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... [A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly ... with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation) due to a …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... [A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly ... with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation) due to a …
Exemestane
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Approved
Investigational
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-5-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Paliperidone
Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Iupac: … [4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a] …
Matched Description: … intramuscular injection, and a twice-yearly gluteal injection. ... The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. ... It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination …
Matched Description: … intramuscular injection, and a twice-yearly gluteal injection. ... The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. ... It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Description: … Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein ... [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval ... offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib] due to a …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Artemisia vulgaris root
Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne ... [L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with …
Oxybenzone
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Description: … It is a derivative of benzophenone. ... It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays …
Matched Mixtures name: … A-cream ... Hope In A Tinted Moisturizer ... Hope In A Jar SPF 25 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … A-cream ... Hope In A Tinted Moisturizer ... Hope In A Jar SPF 25 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
D-glucose
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... the World Health Organization's List of Essential Medicines, the most important medications needed in a …
Matched Mixtures name: … Acd-A ... Anticoagulant Citrate Dextrose A ACD-A ... Acd A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Acd-A ... Anticoagulant Citrate Dextrose A ACD-A ... Acd A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polysorbate 80
Polysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where it acts as an emulsifier, a solubilizer in many foods, including bread, cake mix, salad dressing, shortening oil and...
Approved
Matched Description: … of a solubilizing agent. ... Polysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant ... It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Amantadine
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Description: … An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. …
Matched Categories: … Influenza A M2 Protein Inhibitor …
Matched Categories: … Influenza A M2 Protein Inhibitor …
Methylchloroisothiazolinone
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness,...
Approved
Experimental
Matched Description: … Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. ... Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial ... It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Description: … Amprenavir is a protease inhibitor used to treat HIV infection. …
Displaying drugs 3051 - 3075 of 12063 in total