Displaying drugs 901 - 925 of 14030 in total
Oprelvekin
Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Description: … With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids ... in length in comparison to the natural IL-11, which is 178 amino acid long. ... In mice and nonhuman primate studies of animals with moderate and severe myelosuppression, in addition …
Flupentixol
Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … It is approved for use in Canada and other countries around the world, but not in the US. ... It is used for the management of chronic schizophrenia in patients whose main manifestations do not include ... It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. …
Sodium stibogluconate
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world …
Balsalazide
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. …
Sodium iodide
Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition but is more commonly used in veterinary medicine. Radiolabelled compound, DB09293, is used as a diagnostic tool to evaluate thyroid function...
Approved
Matched Description: … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition ... [L2065] but is more commonly used in veterinary medicine. ... Sodium iodide is a water-soluble ionic compound with a crystal lattice. …
Lifitegrast
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Description: … Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) ... The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. ... It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Plecanatide
Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Description: … Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation ... It should not be used in children less than six years of age, and should be avoided in patients six years …
Matched Categories: … Drugs for Constipation …
Matched Categories: … Drugs for Constipation …
Efalizumab
Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. The FDA approved efalizumab in 2003. It was later withdrawn...
Approved
Investigational
Withdrawn
Matched Description: … Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ... ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. ... It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy …
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Midodrine
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Description: … It is used as a vasoconstrictor agent in the treatment of hypotension. …
Human papillomavirus type 58 L1 capsid protein antigen
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Description: … Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... (VLPs) of the major capsid (L1) protein of HPV Type 58 which are produced by separate fermentations in …
Matched Mixtures name: … GARDASIL 9 SUSPENSION FOR INJECTION …
Matched Mixtures name: … GARDASIL 9 SUSPENSION FOR INJECTION …
Ambrosia artemisiifolia pollen
Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Description: … Ambrosia artemisiifolia pollen is mainly used in allergenic testing. …
Tragacanth
Tragacanth allergenic extract is used in allergenic testing.
Approved
Matched Description: … Tragacanth allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Nisoldipine
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Description: … Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. ... Nisoldipine may be used in alone or in combination with other agents in the management of hypertension ... acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Iodide I-123
Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect...
Approved
Matched Description: … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for ... Radioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h ( ... hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared …
Strontium chloride
Strontium chloride (SrCl2) is a salt of strontium and chloride. SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession [A33167, A33168]. This kind of barrier protection for tooth hypersensitivity has, however, been...
Approved
Matched Description: … SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin ... Such strontium chloride toothpaste formulations may subsequently not be available for sale anymore in ... Strontium chloride (SrCl2) is a salt of strontium and chloride. …
Estradiol benzoate
Estradiol Benzoate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex ... Estradiol Benzoate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously ... Estradiol benzoate is not currently available in Canada or the US. …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Description: … Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex ... Estradiol Benzoate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously ... Estradiol benzoate is not currently available in Canada or the US. …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Description: … It is a phenylindole derivative used in the treatment of schizophrenia. ... It was first marketed in 1996 in several European countries before being withdrawn two years later because ... Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. …
Perflubutane
Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Matched Description: … testing; currently the leading procedure for detecting coronary heart disease. ... Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis ... It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Tioconazole
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus ... In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Flurazepam
A benzodiazepine derivative used mainly as a hypnotic.
Approved
Illicit
Investigational
Matched Description: … A benzodiazepine derivative used mainly as a hypnotic. …
Bepotastine
Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe Seiyaku Co., Ltd. under the brand name Talion. It is available...
Approved
Matched Description: … Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus ... Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. ... It is available in oral and opthalmic dosage forms in Japan. …
Calcium alginate
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 901 - 925 of 14030 in total