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Displaying drugs 376 - 400 of 14945 in total

Tamsulosin

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … in the prostate and bladder, where these receptors are most common. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect ... [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Mixtures name: … Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide …
Matched Categories: … propranolol and thiazides ... Beta Blocking Agents and Thiazides ... propranolol and other combinations ... Beta Blocking Agents, Non-Selective, and Thiazides …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Lubricant and Redness Reliever ... Eye Drops Redness and Dry Eye Relief ... Eye Drops Redness and Dry Eye Relief …
Matched Categories: … Decongestants and Antiallergics …

Silicon

Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).
Approved
Investigational
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Rocky Mountain Multiple Vit and Min Mega Tab ... Calcium With Mg Zn Mn Cu CR Si and Vit. C & D …
Matched Categories: … Diet, Food, and Nutrition …

Equus caballus hair

Horse hair is used in allergenic testing.
Approved
Matched Mixtures name: … Horse Hair and Dander ... Animal Allergens, AP Horse Hair and Dander ... Animal Allergens, AP Horse Hair and Dander …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Sucralfate

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Description: … , bile salts, alcohol, and acetylsalicylic acid (aspirin), among other substances [A177655, F4519]. ... agent_, protecting cells in the gastrointestinal tract from damage caused by agents such as gastric acid ... It is sold under many brands and is available in both tablet and suspension forms. …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Rizatriptan

Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …

Ritonavir

Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Description: … formulations and as capsules. ... - and Health Canada-approved product Technivie. ... protease inhibitors such as [DB09297] and overall drug exposure. …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir ... ombitasvir, paritaprevir and ritonavir …

Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)

Approved
Investigational
Matched Mixtures name: … Diphtheria and Tetanus Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed …

Fluocinonide

A topical glucocorticoid used in the treatment of eczema.
Approved
Investigational
Matched Mixtures name: … Fluocinonide 0.05% / Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% …
Matched Categories: … fluocinonide and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Bos taurus dander

Bos taurus dander allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, AP Cattle Hair and Dander ... Animal Allergens, AP Cattle Hair and Dander ... Animal Allergens, AP Cattle Hair and Dander …

Sodium phosphate, monobasic, unspecified form

Approved
Matched Mixtures name: … Up and Up Ready To Use Enema ... Pure and Gentle Laxative ... Foster and Thrive Ready to Use Saline Laxative …

Cantharidin

Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Matched Description: … genitourinary tracts, along with electrolyte and renal function disturbance in humans and animals [A32891 ... [A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin ... effectiveness at treating topical skin conditions like warts than other commonly available vesicant and …
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …

Podophyllin

Podophyllin is a resin extracted from the roots of Podophyllum peltatum (American mandrake) and Podophyllum emodi, which contains numerous compounds, amongst which is podophyllin (as well as the drug podophyllotoxin). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Approved
Matched Iupac: … 7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-2H,5H,6H,7H,8H-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid …
Matched Description: … Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum …
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …
Matched Categories: … Skin and Mucous Membrane Agents …

Canis lupus familiaris hair

Domestic dog hair is used in allergenic testing.
Approved
Matched Mixtures name: … Dog Hair and Epithelia ... Animal Allergens, Dog Hair and Dander Canis spp. ... Animal Allergens, Dog Hair and Dander Canis spp. …

Ibrexafungerp

Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Iupac: … 1H-1,2,4-triazol-1-yl]-17-oxapentacyclo[13.3.3.0^{1,14}.0^{2,11}.0^{5,10}]henicos-2-ene-6-carboxylic acid …
Matched Description: … A235384] Ibrexafungerp is orally bioavailable compared to the echinocandins [caspofungin], [micafungin], and …

Mafenide

Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder...
Approved
Vet approved
Withdrawn
Matched Description: … It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep …
Matched Categories: … Folic Acid Antagonists ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Valganciclovir

Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Approved
Investigational
Matched Description: … After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …

Magnesium citrate

Magnesium citrate is a low volume and osmotic cathartic agent. The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used. Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under...
Approved
Matched Description: … Magnesium citrate is a low volume and osmotic cathartic agent. …
Matched Mixtures name: … Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iu ... Calcium and Magnesium Citrate With Vitamin D …
Matched Categories: … Blood and Blood Forming Organs ... Alimentary Tract and Metabolism ... Blood Substitutes and Perfusion Solutions …

Bethanechol

Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Iupac: … 4-[(2R,3R)-2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoic acid …
Matched Description: … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially …

Rifamycin

Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Description: … was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid ... Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] ... Some small modifications where performed in this inactive compound and with the creation of rifamycin …
Matched Categories: … Alimentary Tract and Metabolism …

Propoxycaine

Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride . This drug was removed from the US market in 1996. Although no longer available in the United States, this medication was used in combination...
Approved
Matched Description: … Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration …

Oxybenzone

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Description: … It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays …
Matched Mixtures name: … Silk and Shine ... Skin So Soft Firm and Restore Neck and Chest Treatment ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit …
Displaying drugs 376 - 400 of 14945 in total