Displaying drugs 226 - 250 of 3214 in total
Coal tar
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
It has been...
Approved
Matched Description: … It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea ... Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and ... and eczema. …
Matched Mixtures name: … Pete and Pedro ... PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT ... Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Matched Mixtures name: … Pete and Pedro ... PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT ... Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Panax notoginseng root
Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng) ... Notoginseng Root ... San Qi Root …
Matched Name: … Panax notoginseng root …
Matched Description: … Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Name: … Panax notoginseng root …
Matched Description: … Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. …
Water
Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and ... rain, and is the major constituent of the fluids of organisms. ... its solid state, ice; and gaseous state, steam (water vapor). …
Matched Mixtures name: … Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... Medium Cuts and Scratches ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … API IPHA ... Salinaax Eye Wash and Skin Flush ... Xpect First aid Buffered Eye and Skin …
Matched Mixtures name: … Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... Medium Cuts and Scratches ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … API IPHA ... Salinaax Eye Wash and Skin Flush ... Xpect First aid Buffered Eye and Skin …
Artemisia vulgaris pollen
Artemisia vulgaris pollen is the pollen of the Artemisia vulgaris plant. Artemisia vulgaris pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Sagebrush, Mugwort Artemisia vulgaris …
Ambrosia artemisiifolia pollen
Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Short and Giant Ragweed Pollen Mix ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …
Polyethylene glycol 400
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … various derivatives and have various functions. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used …
Matched Mixtures name: … Basic Care Eye ... Basic Care Eye ... Redness reliever and Lubricant …
Matched Products: … Foster and Thrive Dry Eye Relief …
Matched Mixtures name: … Basic Care Eye ... Basic Care Eye ... Redness reliever and Lubricant …
Matched Products: … Foster and Thrive Dry Eye Relief …
Dopamine
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. ... Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating …
Matched Mixtures name: … Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … DOPamine Hydrochloride and Dextrose ... Dopamine Hydrochloride and Dextrose ... DOPamine HYDROCHLORIDE AND DEXTROSE …
Matched Mixtures name: … Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … DOPamine Hydrochloride and Dextrose ... Dopamine Hydrochloride and Dextrose ... DOPamine HYDROCHLORIDE AND DEXTROSE …
Isopropyl alcohol
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. …
Matched Mixtures name: … Anti-bacterial Alcohol-based Hand and Skin Disinfectant ... I D Anti Bacterial Alcohol Based Hand and Skin Disinfectant ... I D Sept Anti Bacterial Alcohol Based Hand and Skin Disinfectant …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Clean Skin club Hydrating Hand Sanitizer with Aloe Vera and Hyaluronic Acid ... Roots Aromatherapy ... Tintura de Arnica …
Matched Mixtures name: … Anti-bacterial Alcohol-based Hand and Skin Disinfectant ... I D Anti Bacterial Alcohol Based Hand and Skin Disinfectant ... I D Sept Anti Bacterial Alcohol Based Hand and Skin Disinfectant …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Clean Skin club Hydrating Hand Sanitizer with Aloe Vera and Hyaluronic Acid ... Roots Aromatherapy ... Tintura de Arnica …
Cefoxitin
Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Salts name: … Cefoxitin sodium …
Matched Products: … Cefoxitin and Dextrose …
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Salts name: … Cefoxitin sodium …
Matched Products: … Cefoxitin and Dextrose …
Loratadine
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Loratadine and Pseudoephedrine Sulfate ... Loratadine and Pseudoephedrine Sulfate ... Loratadine and Pseudoephedrine Sulfate …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Live Better Loratadine ... LORATADINA TABLETAS POR 10 MG ... Up and Up Allergy Relief …
Matched Mixtures name: … Loratadine and Pseudoephedrine Sulfate ... Loratadine and Pseudoephedrine Sulfate ... Loratadine and Pseudoephedrine Sulfate …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Live Better Loratadine ... LORATADINA TABLETAS POR 10 MG ... Up and Up Allergy Relief …
Amaranthus retroflexus pollen
Amaranthus retroflexus pollen is the pollen of the Amaranthus retroflexus plant. Amaranthus retroflexus pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Pigweed, Rough Redroot Amaranthus retroflexus …
Ergidina
Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …
Tarlatamab
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Tolnaftate
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester ... Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Up and Up Soothing Antifungal ... Up and Up Antifungal ... Fungi Nail Toe and Foot …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Up and Up Soothing Antifungal ... Up and Up Antifungal ... Fungi Nail Toe and Foot …
Potassium carbonate
Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent reaction with carbon dioxide. It presents a large capacity to absorb moisture.
Approved
Matched Synonyms: … Carbonic acid, dipotassium salt ... Carbonate of potash ... Potassium carbonate …
Matched Name: … Potassium carbonate …
Matched Iupac: … dipotassium carbonate …
Matched Description: … Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly …
Matched Mixtures name: … Buffered Vitamin C Powder With Ca Mg and K ... Vit C W Calc-mag and Potass Powder ... ZOLFO E POTASSIO CARBONATO NEW.FA.DEM. …
Matched Categories: … Carbonic Acid …
Matched Products: … Moonstar Face and Body Mist …
Matched Name: … Potassium carbonate …
Matched Iupac: … dipotassium carbonate …
Matched Description: … Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly …
Matched Mixtures name: … Buffered Vitamin C Powder With Ca Mg and K ... Vit C W Calc-mag and Potass Powder ... ZOLFO E POTASSIO CARBONATO NEW.FA.DEM. …
Matched Categories: … Carbonic Acid …
Matched Products: … Moonstar Face and Body Mist …
Bismuth subsalicylate
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … Basic bismuth salicylate …
Matched Description: … of [salicylic acid] linked to trivalent [bismuth cation]. ... [A230733] Bismuth subsalicylate has been around for over 100 years: it was originally developed in 1901 ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. …
Matched Mixtures name: … Bismuth Tablets With Calcium Carbonate ... Chewable Bismuth Tablets With Calcium Carbonate ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …
Matched Description: … of [salicylic acid] linked to trivalent [bismuth cation]. ... [A230733] Bismuth subsalicylate has been around for over 100 years: it was originally developed in 1901 ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. …
Matched Mixtures name: … Bismuth Tablets With Calcium Carbonate ... Chewable Bismuth Tablets With Calcium Carbonate ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …
Chlorine dioxide
Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Description: … Chlorine Dioxide has been used in trials studying the treatment of Halitosis. …
Matched Products: … Disinfectant and Sanitizer …
Matched Products: … Disinfectant and Sanitizer …
Pectin
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1 ... [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids …
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry ... Burts Bees Throat Soothing ... Throat Coat Lemon Ginger Echinacea …
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry ... Burts Bees Throat Soothing ... Throat Coat Lemon Ginger Echinacea …
Cyclomethicone 5
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and ... Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
Matched Products: … Mefactory Super Clear Lip And Eye Remover …
Matched Products: … Mefactory Super Clear Lip And Eye Remover …
Eugenol
Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. Although not currently available in any FDA-approved...
Approved
Matched Description: … for root canal sealing and pain control. ... It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide ... Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and …
Matched Categories: … Caffeic Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Walgreens Natural Eugenol/Toothache Medication with cotton pellets and tweezers …
Matched Categories: … Caffeic Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Walgreens Natural Eugenol/Toothache Medication with cotton pellets and tweezers …
Triptorelin
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary Hormone-Releasing Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary Hormone-Releasing Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … Nicotinic acid amide …
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Bandha Who and Y Zone Serum ... Feminique W Iron and Calcium Tab ... Hello Care Pore and Sebum Ampoule Mask …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Bandha Who and Y Zone Serum ... Feminique W Iron and Calcium Tab ... Hello Care Pore and Sebum Ampoule Mask …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
Cetrorelix
Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Pituitary Hormone-Releasing Hormones …
Matched Products: … Cetrotide 0.25 mg powder and solvent for solution for injection …
Matched Products: … Cetrotide 0.25 mg powder and solvent for solution for injection …
Leuprolide
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing ... clinical efficacy of leuprolide in diverse conditions, including advanced prostate cancer, endometriosis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary Hormone-Releasing Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... leuprorelin and bicalutamide …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary Hormone-Releasing Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... leuprorelin and bicalutamide …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg …
Capsicum
Capsicum (Chili pepper) allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Zaxs Aches and Pain …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Displaying drugs 226 - 250 of 3214 in total