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Displaying drugs 2651 - 2675 of 9613 in total

Levomenthol

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration …
Matched Mixtures name: … GLYCERIN OF THYMOL ... MENTOLCLARIDERM (R) ... FRICSOL (R) LINEMENTO …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Mixtures name: … FOLISTER COMPLEX HAIR LOTION (R) ... FOLISTER COMPLEX HAIR LOTION (R) …
Matched Products: … PROCORT(R) LOCIÓN CAPILAR …

Betrixaban

Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Description: … non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable …

Eravacycline

Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Description: … Eravacycline, known as _Xerava_ by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of ... This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase ... Eravacycline has demonstrated superior potency to that of antibiotics that are currently being marketed …
Matched Categories: … combinations of tetracyclines …

Acitretin

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Description: … It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared ... An oral retinoid effective in the treatment of psoriasis. …
Matched Categories: … Retinoids for Treatment of Psoriasis …

Viomycin

Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomycin was derived from the actinomycete Streptomyces puniceus.
Approved
Matched Categories: … Drugs for Treatment of Tuberculosis …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Iopodic acid

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Description: … Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by ... [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque …
Matched Categories: … Diagnostic Uses of Chemicals …

Iotrolan

Nonionic, isotonic contrast medium designed for intrathecal use.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Piritramide

Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
Approved
Investigational
Matched Description: … Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. ... Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Gefapixant

It has been estimated that 5-10% of adults globally suffer from chronic cough, which is defined as a cough lasting longer than eight weeks. A subset of these patients remain symptomatic despite thorough investigation and treatment, termed refractory chronic cough (RCC) if they have a cough that does not respond...
Approved
Investigational
Matched Description: … It has been estimated that 5-10% of adults globally suffer from chronic cough, which is defined as a ... [L48601] A subset of these patients remain symptomatic despite thorough investigation and treatment, ... [L48596,L48591] It is the first therapy to be approved for the treatment of RCC or UCC in the EU. …
Matched Categories: … combinations of sulfonamides …

Fecal microbiota

Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Description: … [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring ... Recurrent CDI has a high risk of mortality and a high failure rate. ... For this type of therapy to be efficient, qualified donors must be selected. …

Bacampicillin

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … the biosynthesis of cell wall mucopeptides. ... Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of …
Matched Categories: … combinations of penicillins …

Pivampicillin

Pivalate ester analog of ampicillin.
Approved
Matched Description: … Pivalate ester analog of ampicillin. …
Matched Categories: … combinations of penicillins …

Normethadone

Normethadone is used as an opioid antitussive in combination with DB11610. It is marketed in Canada by Valeant under the tradename Cophylac.
Approved
Illicit
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Iomeprol

Iomeprol has been investigated for the diagnostic of Coronary Artery Disease.
Approved
Investigational
Matched Description: … Iomeprol has been investigated for the diagnostic of Coronary Artery Disease. …
Matched Categories: … Diagnostic Uses of Chemicals …

Iobitridol

Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.
Approved
Investigational
Matched Description: … Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease …
Matched Categories: … Diagnostic Uses of Chemicals …

Amitriptylinoxide

Amitriptylinoxide has been used in trials studying Major Depression.
Approved
Investigational
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tizanidine

Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Description: … of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. ... excitatory neurotransmitters that cause firing of neurons promoting muscle spasm [FDA label]. ... Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects …
Matched Products: … CIMBRAR(R) SR CAPSULA DE LIBERACIÓN PROGRAMADA …

Fenoldopam

A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Approved

Sertaconazole

Sertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.
Approved
Investigational
Matched Description: … Sertaconazole nitrate is an antifungal medication of the imidazole class. ... It is available in topical formulations for the treatment of skin infections such as athlete's foot. …
Matched Categories: … combinations of imidazole derivatives …

Ticarcillin

An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Categories: … combinations of penicillins …

Dexpanthenol

Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation ... an essential component of a normally functioning epithelium. …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Pafolacianine

Pafolacianine, or OTL38, is a folate analogue conjugated with a fluorescent dye that absorbs light in the near-infrared (NIR) spectrum within a range of 760 nm to 785 nm, with a peak absorption of 776 nm. It emits fluorescence within a range of 790 nm to 815 nm with a...
Approved
Investigational
Matched Description: … It emits fluorescence within a range of 790 nm to 815 nm with a peak emission of 796 nm. ... for better imaging and detection of tumours. ... 760 nm to 785 nm, with a peak absorption of 776 nm. …
Matched Categories: … Diagnostic Uses of Chemicals …

Naloxone

Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Iupac: … 10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18 …
Matched Description: … within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. ... [L33724] Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression ... the opioid effect of buprenorphine. …
Matched Mixtures name: … TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA ... TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA …
Matched Products: … EVZIO(R) NALOXONE HCl …
Displaying drugs 2651 - 2675 of 9613 in total