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Displaying drugs 251 - 275 of 10518 in total

Zidovudine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Iupac: … 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … RETROVIR IV FOR INFUSION 1% …

Emicizumab

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Products: … HEMLİBRA 150 MG/ 1 ML S.C. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... HEMLİBRA 30 MG/ 1 ML S.C. ENJEKSİYONLUK ÇÖZELTİ , 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …

Nabilone

Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Iupac: … (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,8H,9H,10H,10aH-benzo[c]isochromen- …
Matched Description: … mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 …
Matched Products: … Canemes 1 mg Kapseln …

Apalutamide

Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Salts cas: … 26970-82-1 …
Matched Mixtures name: … Vege 1 Daily Tab ... DAILY-ONE 45 FILM TABLET …

Glimepiride

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … -(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)-2,5-dihydro-1H-pyrrole-1- …
Matched Mixtures name: … GLUCOVEL 1 ... VELACOM PLUS 1/250 ... AMARYL®M 1 MG/ 500 MG …
Matched Products: … DIAPRIDE-1 TABLET 1 mg ... GLUVAS 1 ... VELACOM 1 …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Salts cas: … 351186-51-1 …
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … EUVAX-B 1 ML FLAKON, 1 ADET ... HBVAXPRO ERİŞKİN 10 MCG/1 ML IM ENJEKSİYON İÇİN SUSPANSİYON İÇEREN FLAKON, 1 ADET ... EUVAX-B 0,5 ML FLAKON, 1 ADET …

Turoctocog alfa pegol

Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Products: … ESPEROCT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... ESPEROCT 1000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... ESPEROCT 1500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Products: … 4-N-1 Wash ... Wrinkless Ct-1 Eye ... Kendall 2-in-1 Cleanser …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Salts cas: … 1416-03-1 …
Matched Mixtures name: … Goyescas Broncovac 1 Cough and Cold ... PRAMOFEN %1 + % 0,25 KREM, 50 GRAM ... OLEDRO 32/ 1/ 0,2 MG/ML PEDIATRIK SURUP, 100 ML …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Neo-synephrine Liq 1% ... Neo Synephrine Nasal Drop 1% ... Neo-synephrine Nasal Drop 1% …

Amylmetacresol

Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils . The acute sore throat (pharyngitis)...
Approved
Matched Products: … Strepsils 1 - Loz …

Flunitrazepam

Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Approved
Illicit
Matched Iupac: … 5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Products: … ROHYPNOL 1 ... Rohypnol 1 mg - Filmtabletten ... ROHYPNOL ROCHE TABLETAS 1 MG …

Treprostinil

Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … 2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen- …
Matched Products: … REMODULIN 1 mg/ml Infusionslösung ... REMODULIN ® INYECCIÓN 1 MG/ML ... Treposa 1 mg/ml Infusionslösung …

Gestrinone

Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and is used primarily in the treatment of endometriosis. Gestrinone was developed in the early 1970s and was tested clinically as...
Approved
Matched Iupac: … (1R,3aS,3bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren …

Fluconazole

Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol …
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... CANDIMAX 150 MG KAPSUL, 1 ADET ... FLUCORAL 150 MG KAPSÜL, 1 ADET …

Dactinomycin

A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo …
Matched Iupac: … 13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro-1H-pyrrolo[2,1-i]1- …

Velaglucerase alfa

Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 …
Matched Products: … VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …

Etelcalcetide

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Iupac: … (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido ... -1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl …
Matched Products: … PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …

Potassium citrate

Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat...
Approved
Investigational
Vet approved
Matched Mixtures name: … PEDIALYTE 45 MEQ CON ZINC ... DAILY-ONE 45 FILM TABLET ... HIDRAPLUS®45 SOLUCIÓN ORAL. …

Lorazepam

Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.
Approved
Matched Products: … LORANS 1 TABLET 1 mg ... LORANS 1 TABLET ... ATIVAN® 1 MG TABLETAS …

Hydrocortisone

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, …
Matched Mixtures name: … Cho-A Care Lot 1% ... HERPAZON % 5 + % 1 KREM, 5 GRAM ... HYDROCORTISONE 1% ET UREA 5% CREAM …
Matched Products: … Barriere HC 1% ... Cortate Ont 1% ... Cortate Crm 1% …

Vinorelbine

Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Products: … RENOVEL 10 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... NAVELBINE 20 MG YUMUSAK KAPSUL, 1 ADET ... NAVELBINE 30 MG YUMUSAK KAPSUL, 1 ADET …

Bevacizumab

There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Products: … ZİRABEV 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ZİRABEV 400 MG/16 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ALTUZAN 100MG/4ML KONSANTRE INFÜZYON COZELTİSİ, 1 ADET …

Argatroban

Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Iupac: … (2R,4R)-1-[(2S)-5-carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Argatra 1 mg/ml Infusionslösung ... Argatroban Accord 1 mg/ml Infusionslösung ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …

Pamidronic acid

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Iupac: … (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid …
Matched Products: … AREDIA 90 MG/10 ML FLAKON, 1 ADET ... ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... PAMIDRONAT DISODYUM DBL 90 MG/10 ML FLAKON, 1 ADET …
Displaying drugs 251 - 275 of 10518 in total