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Displaying drugs 251 - 275 of 1338 in total

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Categories: … Calcium Homeostasis ... Calcium-Regulating Hormones and Agents …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Salts name: … Alendronate calcium ... Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium …

Fospropofol

Fospropofol is a water soluble prodrug and is converted to propofol in the liver. Fospropofol is a short acting hypnotic/sedative/anesthetic agent. Unlike propofol, does not cause injection-site pain as it is unable to activate TRPA1. FDA approved in December 2008. Fospropofol is a Schedule IV controlled substance in the United...
Approved
Illicit
Investigational

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Salts name: … Carvedilol phosphate …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Matched Products: … Carvedilol Phosphate …

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium ... Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are ... associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than other calcium …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine besylate/atorvastatin calcium ... Amlodipine besylate/atorvastatin calcium …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG …

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …
Matched Salts name: … Fingolimod lauryl sulfate …
Matched Categories: … Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …

Nitrendipine

Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Description: … does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. ... Nitrendipine is a calcium channel blocker with marked vasodilator action. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Description: … Lercanidipine is a calcium channel blocker of the dihydropyridine class. …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Atorvastatin

Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Mixtures name: … Amlodipine besylate/atorvastatin calcium ... Amlodipine besylate/atorvastatin calcium ... Amlodipine besylate/atorvastatin calcium …
Matched Salts name: … Atorvastatin calcium ... Atorvastatin calcium trihydrate …
Matched Products: … Atorvastatin Calcium ... Atorvastatin calcium ... ATORVASTATIN CALCIUM …

Amifampridine

Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium ... Amifampridine phosphate is a more stable salt that serves as an active ingredient of EMA-approved Firdapse ... channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations …
Matched Salts name: … Amifampridine phosphate …
Matched Categories: … Potassium Channel Blockers …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Salts name: … Sulfacetamide sodium …
Matched Products: … Sulfacetamide Sodium ... Sodium Sulfacetamide ... Sodium sulfacetamide …

Clevidipine

Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Approved
Investigational
Matched Description: … Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Pralidoxime

Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Description: … hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester …
Matched Mixtures name: … ATNAA atropine and pralidoxime chloride Auto-Injector …
Matched Salts name: … Pralidoxime chloride ... Pralidoxime methyl sulfate …
Matched Products: … Protopam Chloride ... Pralidoxime Chloride ... Protopam Chloride Inj 1gm …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Salts name: … Chloramphenicol sodium succinate …
Matched Products: … Chloromycetin Sodium Succinate ... Chloramphenicol Sodium Succinate ... CHLORAMPHENICOL SODIUM SUCCINATE …

Ziconotide

Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail Conus magus comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because...
Approved
Matched Description: … [L13389] To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA ... collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium ... used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium …
Matched Categories: … Calcium Channel Blockers ... Calcium Channels, N-Type ... Calcium-Regulating Hormones and Agents ... N-Calcium Channel Receptor Antagonists …

Cinnarizine

First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Description: … Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system ... Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …

Patiromer

Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a...
Approved
Investigational
Matched Description: … non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. ... The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate ... Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a …
Matched Salts name: … Patiromer sorbitex calcium …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Binding Activity …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Mixtures name: … Calcium Magnesium Sulfur Silicon - Tab ... Active Calcium Plus Magnesium, Vitamin D and Silicon ... Actical Plus Calcium-magnesium-vitamin D3-silicon Chewable …

Mecobalamin

Approved
Investigational
Matched Mixtures name: … Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …

Zofenopril

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Salts name: … Zofenopril calcium …

Gallium nitrate

Gallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US...
Approved
Investigational
Matched Categories: … Calcium Resorption Inhibitor ... Calcium-Regulating Hormones and Agents …

Doxycycline

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Salts name: … Doxycycline calcium …
Matched Products: … Vibramycin Calcium …

Phenytoin

Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as...
Approved
Vet approved
Matched Salts name: … Phenytoin sodium …
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Phenytoin Sodium ... PHENYTOIN SODIUM ... Extended Phenytoin Sodium …

Phenobarbital

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate, Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Salts name: … Phenobarbital sodium …
Matched Products: … Phenobarbital Sodium ... PHENOBARBITAL SODIUM ... Phenobarbital Sodium Injection, USP …

Pitavastatin

Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Salts name: … Pitavastatin calcium ... Pitavastatin sodium …
Matched Products: … Pitavastatin Calcium …
Displaying drugs 251 - 275 of 1338 in total