Displaying drugs 301 - 325 of 14564 in total
Ancestim
Ancestim is a non-glycosylated recombinant methionyl human stem cell factor. It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine . Ancestim was...
Approved
Investigational
Withdrawn
Matched Description: … It was submitted to the FDA under the status of recommendation for approval with a 10 to 1 votes. ... [T68] It was also approved by Health Canada in 1999 but it is currently under the status of canceled ... It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the …
Triptorelin
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl …
Matched Description: … Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH) ... Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Products: … GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen …
Matched Description: … Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH) ... Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Products: … GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen …
Amphetamine
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Synonyms: … 1-phenyl-2-aminopropane ... rac-(2R)-1-phenylpropan-2-amine …
Matched Iupac: … 1-phenylpropan-2-amine …
Matched Description: … [A18540] The first product of Smith, Kline and French was approved by the FDA on 1976. ... ended up in the black market, producing the initiation of the illicit abuse. ... This use derived into a large overproduction of amphetamine and all the surplus after the war finalized …
Matched Mixtures name: … Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … 1-phenylpropan-2-amine …
Matched Description: … [A18540] The first product of Smith, Kline and French was approved by the FDA on 1976. ... ended up in the black market, producing the initiation of the illicit abuse. ... This use derived into a large overproduction of amphetamine and all the surplus after the war finalized …
Matched Mixtures name: … Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Olaparib
Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Sildenafil
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common …
Matched Categories: … combinations of sulfonamides ... Drugs Used in Erectile Dysfunction …
Matched Products: … A-Sildenafil Tablets 100mg ... VEGIRO 100 MG FILM TABLET,1 ADET ... DEGRA 50 MG FILM KAPLI TABLET, 1 ADET …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common …
Matched Categories: … combinations of sulfonamides ... Drugs Used in Erectile Dysfunction …
Matched Products: … A-Sildenafil Tablets 100mg ... VEGIRO 100 MG FILM TABLET,1 ADET ... DEGRA 50 MG FILM KAPLI TABLET, 1 ADET …
Benzocaine
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve ... [A231219] It is commonly used for local anesthesia in many over the counter products. ... [L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] …
Matched Mixtures name: … CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant ... CVS Health Healing on the Go Kit ... Kank-A …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Blt 1 ... KANK-A ... BABY KANK-A …
Matched Mixtures name: … CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant ... CVS Health Healing on the Go Kit ... Kank-A …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Blt 1 ... KANK-A ... BABY KANK-A …
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor ... [A193797]
Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the ... This led to the development of second-generation triptans, including [almotriptan], [eletriptan], [frovatriptan …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Rabies immune globulin, human
IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine.
Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Description: … rabies have been outlined by the National Advisory Committee on Immunization (NACI), the Advisory Committee ... IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure ... If IMOGAM Rabies Pasteurized is not administered as recommended at the initiation of the post-exposure …
Matched Products: … EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET ... Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze …
Matched Products: … EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET ... Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze …
Umeclidinium
Umeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less...
Approved
Matched Synonyms: … 1-[2-(benzyloxy)ethyl]-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane …
Matched Iupac: … 1-[2-(benzyloxy)ethyl]-4-(hydroxydiphenylmethyl)-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … , and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than 80%. ... by the abundance of the muscarinic subtype 3 (M3) in the airway smooth muscle. ... COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production …
Matched Iupac: … 1-[2-(benzyloxy)ethyl]-4-(hydroxydiphenylmethyl)-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … , and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than 80%. ... by the abundance of the muscarinic subtype 3 (M3) in the airway smooth muscle. ... COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production …
Calcium carbimide
Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of...
Approved
Withdrawn
Matched Synonyms: … Cyanamide, calcium salt (1:1) ... methanediimine, calcium salt (1:1) …
Matched Description: … of alcohol by preventing the breakdown of the metabolic product acetaldehyde. ... Calcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side ... [A31516] This drug was developed by Lederle Cyanamid Canada Inc and approved for marketing in Canada …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Alcohol Dependence …
Matched Description: … of alcohol by preventing the breakdown of the metabolic product acetaldehyde. ... Calcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side ... [A31516] This drug was developed by Lederle Cyanamid Canada Inc and approved for marketing in Canada …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Alcohol Dependence …
Guanethidine
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Matched Synonyms: … 2-(1'-Azacyclooctyl)ethylguanidine ... (2-(Octahydro-1-azocinyl)ethyl)guanidine ... (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine …
Matched Iupac: … N''-[2-(azocan-1-yl)ethyl]guanidine …
Matched Description: … It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes ... depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. ... An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic …
Matched Iupac: … N''-[2-(azocan-1-yl)ethyl]guanidine …
Matched Description: … It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes ... depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. ... An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic …
Pseudoephedrine
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Synonyms: … (+) threo-2-(methylamino)-1-phenyl-1-propanol ... d-psi-2-Methylamino-1-phenyl-1-propanol …
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Description: … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional ... [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823] ... Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic …
Matched Mixtures name: … Z-cof 1 ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu ... COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Description: … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional ... [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823] ... Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic …
Matched Mixtures name: … Z-cof 1 ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu ... COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Sodium cellulose phosphate
Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Description: … [A31694]
This compound is an ion-exchange resin that can not be absorbed by the body. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Treatment of Hypercalcemia …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Treatment of Hypercalcemia …
Ipratropium
Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Description: … product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... [A176957]
Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy ... Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic …
Matched Mixtures name: … Combivent nebuliser solution in unit dose vial ... Duovent Nebuliser solution in Unit Dose Vial 4ml ... NOTECORT 20 MCG / 50 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 1 ADET …
Matched Products: … A-TROFINSA ... Dom-ipratropium 250 Mcg/ml (1 Ml) ... IPRACORT 20 MCG AEROSOL İNHALER, 1 ADET …
Matched Mixtures name: … Combivent nebuliser solution in unit dose vial ... Duovent Nebuliser solution in Unit Dose Vial 4ml ... NOTECORT 20 MCG / 50 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 1 ADET …
Matched Products: … A-TROFINSA ... Dom-ipratropium 250 Mcg/ml (1 Ml) ... IPRACORT 20 MCG AEROSOL İNHALER, 1 ADET …
Succinylcholine
Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its...
Approved
Matched Description: … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous ... lasting between four to six minutes, make succinylcholine particularly useful in the setting of short ... a means of neuromuscular blockade during intubation and surgical procedures. …
Matched Salts cas: … 6101-15-1 …
Matched Products: … Suxamethonium Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze …
Matched Salts cas: … 6101-15-1 …
Matched Products: … Suxamethonium Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze …
Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide ... N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Description: … It is typically used for the treatment of migraine headaches. ... Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. …
Matched Salts cas: … 143388-64-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Description: … It is typically used for the treatment of migraine headaches. ... Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. …
Matched Salts cas: … 143388-64-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Epirubicin
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Synonyms: … (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO ... -L-ARABINO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S-CIS …
Matched Iupac: … )-10-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1- …
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. ... An anthracycline which is the 4'-epi-isomer of doxorubicin. …
Matched Salts cas: … 56390-09-1 …
Matched Categories: … UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Products: … ALRUBIN® 50MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ANTHRACIN 10MG/5ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... ANTHRACIN 50MG/25ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Matched Iupac: … )-10-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1- …
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. ... An anthracycline which is the 4'-epi-isomer of doxorubicin. …
Matched Salts cas: … 56390-09-1 …
Matched Categories: … UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Products: … ALRUBIN® 50MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ANTHRACIN 10MG/5ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... ANTHRACIN 50MG/25ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Micafungin
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Iupac: … {5-[(1S,2S)-2-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25 ... -tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl …
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting ... the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. …
Matched Products: … Micafungin in Sodium Chloride ... MYCAMINE 100 MG INFÜZYONLUK ÇÖZELTI IÇIN TOZ, 1 ADET ... MYACIT 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting ... the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. …
Matched Products: … Micafungin in Sodium Chloride ... MYCAMINE 100 MG INFÜZYONLUK ÇÖZELTI IÇIN TOZ, 1 ADET ... MYACIT 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Alimemazine
A phenothiazine derivative that is used as an antipruritic.
Approved
Vet approved
Matched Description: … A phenothiazine derivative that is used as an antipruritic. …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … PTH 1-34 ... PTH (1-34) …
Matched Description: … teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] ... [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Matched Products: … Teriparatide Acetate (hPTH (1-34)) ... Teriparatid ratiopharm 20 Mikrogramm/80 Mikroliter Injektionslösung in einem vorgefüllten Injektor …
Matched Description: … teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] ... [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Matched Products: … Teriparatide Acetate (hPTH (1-34)) ... Teriparatid ratiopharm 20 Mikrogramm/80 Mikroliter Injektionslösung in einem vorgefüllten Injektor …
Halofantrine
Halofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in the parasite being poisoned by its own waste. Halofantrine has been shown to preferentially block open and...
Approved
Matched Iupac: … 3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol …
Matched Description: … in the parasite being poisoned by its own waste. ... It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting ... It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. …
Matched Description: … in the parasite being poisoned by its own waste. ... It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting ... It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. …
Suprofen
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Description: … It is no longer approved for use in the United States. …
Ramucirumab
Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby ... In contrast to other agents directed against VEGFR-2, ramucirumab binds a specific epitope on the extracellular ... Ramucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a …
Matched Products: … CYRAMZA 100MG/10 ML INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇEREN FLAKON, 1 ADET ... CYRAMZA 500 MG/50 ML İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇEREN FLAKON, 1 ADET …
Matched Products: … CYRAMZA 100MG/10 ML INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇEREN FLAKON, 1 ADET ... CYRAMZA 500 MG/50 ML İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇEREN FLAKON, 1 ADET …
Carindacillin
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Iupac: … (2S,5R,6R)-6-[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1- …
Matched Description: … It is no longer marketed in the United States. ... Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
Matched Categories: … combinations of penicillins …
Matched Description: … It is no longer marketed in the United States. ... Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
Matched Categories: … combinations of penicillins …
Vosoritide
Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans. It results from a gain-of-function missense mutation in FGFR3 that results in a dramatic suppression of bone growth, both in volume and in length.[A242273,A242277] Treatment for achondroplasia includes both surgical and pharmacological interventions, the...
Approved
Investigational
Matched Description: … by endopeptidases - makes it ineffective as a therapeutic intervention,[A242273] the development of ... [A242277] It results from a gain-of-function missense mutation in _FGFR3_ that results in a dramatic ... approved for the treatment of achondroplasia in both regions. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Displaying drugs 301 - 325 of 14564 in total