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Displaying drugs 301 - 325 of 14966 in total

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … Tobramycin in Sodium Chloride …

Nizatidine

A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Matched Description: … A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Vitamin E

In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Description: … Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol ... for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and ... Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally …
Matched Mixtures name: … Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... Champs Multivitamin Plus Folic Acid & Lysine (Orange Flavour) Chewable Tablet ... Vitamin E and Coq10 …
Matched Categories: … Basic Ointments and Protectants ... Diet, Food, and Nutrition …

Bismuth subnitrate

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Description: … is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and …
Matched Categories: … Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Silver sulfadiazine

Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Approved
Vet approved
Matched Description: … Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Eslicarbazepine acetate

Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Description: … stabilizing the inactivated state of voltage-gated sodium channels, thus preventing their return to ... Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and ... Eslicarbazepine acetate is marketed as Aptiom in North America and Zebinix or Exalief in Europe. …
Matched Categories: … Eslicarbazepine and prodrugs ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Eslicarbazepine

Eslicarbazepine is an anti-epileptic medication available commercially as eslicarbazepine acetate.
Approved
Matched Categories: … Eslicarbazepine and prodrugs ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Pentagastrin

A synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. It has also been used as a diagnostic aid.
Approved
Matched Iupac: … yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid …
Matched Description: … It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Categories: … Enzymes and Coenzymes ... Uric Acid-specific Enzyme …

Iron

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched Description: … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... Multi Vitamin, Iron and Fluoride ... Multi-Vitamin Fluoride and Iron Drops …
Matched Categories: … iron, vitamin B12 and folic acid ... iron, multivitamins and folic acid ... Diet, Food, and Nutrition ... multivitamins and iron ... iron and multivitamins …

Pramocaine

Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect …
Matched Mixtures name: … Bite and Itch ... Up and Up Hemorrhoidal ... Antibiotic, Pain and Scar …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and ... still ongoing, much of the evidence for ivermectin in COVID-19 relies on pre-print _in vitro_ data, and …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep …

Meradimate

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Mixtures name: … Sodium Sulfacetamide Sulfur ... Principal Secret Reclaim Sunscreen For Face and Body SPF 30 …

Prednisolone acetate

Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved

Amylocaine

Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Description: … and prilocaine in the 1940s and 1950s superseded and made the use of amylocaine obsolete. ... and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute [L1882]. ... clinical use of newer, more effective, and even safer local anesthetics like lidocaine, bupivicaine, …

Aluminium phosphate

Approved
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Aluminum and magnesium containing antacids …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... polythiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Triheptanoin

Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly.[A214812,A214817] Complications in lc-FAOD patients...
Approved
Investigational
Matched Description: … with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly ... source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid ... [L14612] In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …

Ethinylestradiol

Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Matched Description: … Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering …
Matched Mixtures name: … Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol …
Matched Categories: … Hormones and Related Agents ... dienogest and ethinylestradiol ... gestodene and ethinylestradiol ... megestrol and ethinylestradiol ... megestrol and ethinylestradiol …

Acetyl sulfisoxazole

Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines ... and pyrimidines, resulting in cell growth arrest and cell death [L2788]. ... , which is the precursor of folic acid. …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Coagulation Factor IX Human

Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion …

Insulin lispro

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human insulin in that the amino acid ... and proteolysis among many other functions. ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …

Fludrocortisone

Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and …
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Plasma protein fraction (human)

The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Description: … some electrolytes such as sodium, potassium and chloride. ... [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains ... protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Methantheline

Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Matched Description: … Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... Gastric Acid Lowering Agents …
Displaying drugs 301 - 325 of 14966 in total