Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 301 - 325 of 12637 in total
Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Approved
Matched Synonyms: … 4-Aminoclonidine …
Matched Iupac: … 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Iopidine 1% …
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Matched Synonyms: … 1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl] ... 2-[3,5-Dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro- …
Matched Iupac: … 2-(3,5-dichloro-4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro …
Matched Description: … non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). ... On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one ... 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine ... 4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Description: … Haloperidol is indicated for the treatment of the manifestations of several psychotic disorders including ... for the management of the "positive" symptoms of schizophrenia including hallucinations, hearing voices ... However, this class of drugs is also limited by the development of movement disorders induced by dopamine-blockade …
Matched Products: … HALOPERIDOL-NEURAX 4 MG ... ICIN COZELTI 1 ML 1 AMPUL ... ฮาล็อกซ์ 1
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Iupac: … 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaene …
Matched Description: … Despite its effectiveness in treating both positive and negative symptoms of schizophrenia, clozapine ... various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of ... [A256713,A256718] However, continued evidence of its effectiveness led to clozapine's eventual reintroduction …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Approved
Investigational
Withdrawn
Matched Iupac: … 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide …
Matched Description: … ., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke …
Matched Categories: … combinations of sulfonamides ... Heterocyclic Compounds, 1-Ring …
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Synonyms: … d-13β-Ethyl-17α-ethynyl-17β-acetoxygon-4-en-3-one oxime ... (17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime ... (+)-13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one oxime acetate (ester) …
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate ... (1R,3aS,3bR,7E,9aR,9bS,11aS)-11a-ethyl-1-ethynyl-7-(hydroxyimino)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Matched Description: … [A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Synonyms: … N(1)-(1-phenylpyrazol-5-yl)sulfanilamide ... 1-phenyl-5-sulfanilamidopyrazole ... 5-sulfanilamido-1-phenylpyrazole …
Matched Iupac: … 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide …
Matched Categories: … combinations of sulfonamides ... Heterocyclic Compounds, 1-Ring …
Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational
Matched Iupac: … (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)methyl dodecanoate …
Matched Description: … Affecting about 1% of the adult population in the United States and approximately 26 million people worldwide ... schizophrenia resulted in improvement of positive and negative symptoms scores at day 85 of treatment ... for immediate initiation of Aristada at any dose. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Synonyms: … (+)-2,2'-(ethylenediimino)di-1-butanol ... (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine …
Matched Iupac: … (2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl]amino}ethyl)amino]butan-1-ol …
Matched Description: … [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of ... indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of
Matched Mixtures name: … ริมสตาร์ 4 - FDC ... AkuriT-4 TABLET …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Iupac: … 2-(4-{3-[(9Z)-2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … signs of anxiety. ... Flupentixol is an antipsychotic drug of the thioxanthene group. ... by esterification of cis(Z)‐flupentixol with decanoic acid. …
Matched Salts cas: … 30909-51-4
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … FLUANXOL 1 MG ... SOLUSYON, 1 ADET ... Flupentixol Bayer 1 mg Filmtabletten …
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Synonyms: … 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine …
Matched Iupac: … dimethyl(2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. ... certain natural substances that cause pain, nausea, and other symptoms of migraine. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Synonyms: … (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol …
Matched Iupac: … (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Description: … over the course of 24 hours. ... Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease ... It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Rotigotin UCB 1 mg/24 Stunden transdermales Pflaster ... Rotigotin Gebro 1 mg/24 Stunden transdermales Pflaster ... NEUPRO® 4 MG /24 H …
Polyquaternium-10 is a quaternized hydroxyethyl cellulose and a polycationic polymer. It is commonly found in cosmetics and personal care products to mainly reduce static electricity and form films.
Approved
Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium...
Approved
Investigational
Matched Description: … diseases.Samarium Sm 153 lexidronam is used to help relieve the bone pain that may occur with certain kinds of ... radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide relief of ... Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of
Matched Salts cas: … 176669-18-4
Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation,...
Approved
Investigational
Matched Synonyms: … 4-Pyrimidinecarboxamide, 6-amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino ... 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl ... 6-amino-5-chloro-N-[1R)-1-[5-[[[5-hloro-4-(trifluoromethyl)-2pyridinyl]amino]carbonyl]-2-thiazoyl]ethyl …
Matched Iupac: … 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl) ... ethyl]pyrimidine-4-carboxamide …
Matched Description: … therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. ... [A263597] It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Synonyms: … 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE ... 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE- ... 5-PYRIMIDINECARBOXAMIDE, 2-AMINO-N-(2,3-DIHYDRO-7-METHOXY-8-(3-(4-MORPHOLINYL)PROPOXY)IMIDAZO(1,2-C)QUINAZOLIN …
Matched Iupac: … 2-amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2H,3H-imidazo[1,2-c]quinazolin-5-yl}pyrimidine-5-carboxamide …
Matched Description: … A261730] Copanlisib was granted accelerated approval by the FDA in September 2017 for the treatment of
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Synonyms: … 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone …
Matched Iupac: … 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one …
Matched Description: … seasonal allergic rhinitis in patients 6 years of age and older. ... Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of ... allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZEP NASAL SPRAY 1 mg/ml ... Azedil 1 mg/ml Nasenspray ... Azelastin POS 1 mg/ml Nasenspray, Lösung …
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … dryness of the eye [L1785]. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim. …
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl ... -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Salts cas: … 153773-82-1
Matched Products: … ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET ... INVANZ FOR INJECTION 1 g/vial …
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Synonyms: … 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of ... [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms ... reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the treatment of
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Synonyms: … ]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid ... (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl …
Matched Iupac: … 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine …
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists...
Approved
Investigational
Matched Description: … Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. ... Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated ... (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Iupac: … (1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo …
Matched Description: … pending approval for the treatment of bipolar disorder in the United States. ... Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … 4-(4-aminophenylsulfonyl)aniline ... 4-(4-amino-benzenesulfonyl)-phenylamine ... 4-(4-aminophenylsulfonyl)benzenamine …
Matched Iupac: … 4-(4-aminobenzenesulfonyl)aniline …
Matched Description: … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of ... It is also used with pyrimethamine in the treatment of malaria. ... A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Mixtures name: … Dapsone 6% / Niacinamide 4% ... Dapsone 8.5% / Niacinamide 4% ... 011504 Dapsone 8.5% / Niacinamide 4% …
Matched Categories: … Drugs for Treatment of Lepra …
Displaying drugs 301 - 325 of 12637 in total