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Displaying drugs 326 - 350 of 6246 in total
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched International brands: … Decortin H
Matched Synonyms: … delta(1)-Hydrocortisone ... delta(1)-Dehydrocortisol ... delta(1)-Dehydrohydrocortisone …
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, ... 5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Description: … Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Matched Mixtures name: … CHLORAMFECORT-H
Matched Products: … LINOLA H N ... LINOLA H FETT N ... อาร์พี-โซโลน 2
Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide Indium In-111 during imaging to evaluate...
Approved
Matched Description: … Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen ... (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue ... When linked to pendetide, capromab is used as a chelating agent for the radionuclide [Indium In-111] …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.
Approved
Withdrawn
Matched Iupac: … dimethyl(2-methyl-3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)amine …
Matched Description: … Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. …
Belumosudil is used in the treatment of chronic graft-versus-host disease (GVHD) and has been investigated for the treatment of pulmonary arterial hypertension. It is an inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK), with significantly more selectivity for ROCK2 as compared to ROCK1 (IC50 100 nM vs. 3 μM, respectively). In...
Approved
Investigational
Matched Iupac: … 2-(3-{4-[(1H-indazol-5-yl)amino]quinazolin-2-yl}phenoxy)-N-(propan-2-yl)acetamide …
Matched Description: … ROCK), with significantly more selectivity for ROCK2 as compared to ROCK1 (IC50 100 nM vs. 3 ... [L34749] In the treatment of GVHD, a condition in which donor T-cells begin to attack recipient tissues …
Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Iupac: … 9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1S,3aS,3bS,5S,9aR,9bS,10S,11aS)-1-acetyl-10-hydroxy-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H, …
Matched Description: … Medrysone is a corticosteroid used in ophthalmology. …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and …
Matched Mixtures name: … Lactate 1-2-3 Injection ... Haemosol H-208 ... Haemosol H-207
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Glucose B. Braun 50 mg/ml Infusionslösung ... Glucose B. Braun 100 mg/ml Infusionslösung ... Glucose B. Braun 200 mg/ml Infusionslösung …
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched International brands: … Tricowas B
Matched Synonyms: … 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrrole ... 2-methyl-3-(2-hydroxyethyl)-4-nitroimidazole ... 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Description: … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. ... antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a
Matched Salts cas: … 69198-10-3
Matched Mixtures name: … Metronidazole 1% / Mupirocin 2% ... Metronidazole 1% / Mupirocin 2% ... Metronidazole 1% / Mupirocin 2% / …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Metrogel 1% ... METRONIDAZOLO B. BRAUN ... Metronidazol B. Braun 5 mg/ml Infusionslösung …
Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Iupac: … 1-[(3S)-3-({6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-yl}amino ... )pyrrolidin-1-yl]propan-1-one …
Matched Description: … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). ... approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3- ... [L45758] APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Synonyms: … 4-chloro-1-hydroxy-3,5-dimethylbenzene ... 2-Chloro-m-xylenol ... 2-chloro-5-hydroxy-m-xylene …
Matched Mixtures name: … Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner ... Cortane-B ... Cortaine -B Aqueous …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … E 2 Sanitizing Hand Soap Liq 3% ... Germ A Stat ... Victoria Bay …
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched International brands: … My-B-Den …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Description: … #39;-, 3'-, or 5'-position. ... acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2& ... was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased …
Matched Products: … POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION PARA ADMINISTRACIÓN OFTALMICA …
Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Tasonermin is recombinant soluble form tumor necrosis factor α produced via Escherichia coli cell culture. It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft...
Approved
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Iupac: … methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate …
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and …
Matched Mixtures name: … KLOGEL-A 75/75 MG KAPSUL, 30 ADET ... KLOGEL-A 75/75 MG KAPSUL, 90 ADET ... KLOGEL-A 75/100 MG KAPSUL, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil ... 2'-Deoxy-5-fluorouridine …
Matched Iupac: … 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Approved
Investigational
Matched Iupac: … 1,4-diethyl 2-{[dimethoxy(sulfanylidene)-lambda5-phosphanyl]sulfanyl}butanedioate …
Matched Description: … Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-FLEAZ SHAMPOO 1% w/w …
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER ... Essential Solution Vita A Mask Sheet ... LIPOFUNDIN N EMULSION FOR INFUSION 20 % …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ruby-Cell 4U B B 10 in 1 ... 3 en 1 Cleanser. Deep Cleansing ... Iaso for Men White EX 2-IN-1 Fluid Supreme …
Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis.
Approved
Matched Iupac: … (1R,2S,10S,11S,13S,14R,15S)-14-(2-chloroacetyl)-1-fluoro-14-hydroxy-2,13,15-trimethyltetracyclo[8.7.0.0 …
Matched Description: … Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions …
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Iupac: … 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate ... (1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-1-(2-chloroacetyl)-9b-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, …
Matched Description: … Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors …
Matched Mixtures name: … Ciclopirox 1% / Clobetasol Propionate 0.05% ... Clobetasol Propionate 0.05% / Levocetirizine Dihydrochloride 2% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Diphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. Antihistamines prevent, but do not reverse, responses mediated by histamine alone. Antihistamines antagonize, in varying degrees, most of the pharmacological effects of histamine, including urticaria and pruritus.
Approved
Investigational
Matched Synonyms: … 4-(benzhydryloxy)-N-methylpiperidine ... 1-methyl-4-piperidyl benzhydryl ether ... 4-(benzhydryloxy)-1-methylpiperidine …
Matched Iupac: … 4-(diphenylmethoxy)-1-methylpiperidine …
Matched Description: … Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites …
Matched Salts cas: … 132-18-3
Matched Mixtures name: … Oradrine 2 Tab ... Solucodan-H ... Eucillin "B" - Salbe …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Synonyms: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... endothelin peptide from constricting the muscles in blood vessels, allowing them to relax and permit a
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Iupac: … ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene- …
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … FLUMAZENIL B. BRAUN ... Flumazenil B. Braun 0,1 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung ... Anexate 1 mg - Injektionslösung …
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Iupac: … -1H-cyclopenta[a]phenanthren-1-ylidene]-6-methylhept-5-enoic acid ... 2-[(1Z,2S,3aS,3bS,5aS,6S,7R,9aS,9bS,10R,11aR)-2-(acetyloxy)-7,10-dihydroxy-3a,3b,6,9a-tetramethyl-hexadecahydro …
Matched Mixtures name: … FUCIDIN H %2 + %1 KREM, 30 G ... DUZEN-B CREAM ... Disuf-B Cream …
Matched Products: … FUSİX %1 VİSKOZ GÖZ DAMLASI, ÇÖZELTİ, 1 TÜP ... FUTARON %1 GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... FUCITHALMIC EYE DROPS 1% …
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone ... 1-beta-D-Arabinofuranosylcytosine ... Cytosine-1-beta-D-arabinofuranoside …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ALDACIT® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ALDACIT® 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ALDACIT® 1000 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). Its high selectivity has been associated with lower discontinuation rates due to adverse events and a lower incidence of atrial fibrillation. Unlike BTK covalent inhibitors, such as ibrutinib, that bind to the cysteine 481...
Approved
Investigational
Matched Synonyms: … (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1h-pyrazole ... 5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-((2s)-1,1,1-trifluoropropan-2-yl)-1h-pyrazole ... 1h-pyrazole-4-carboxamide, 5-amino-3-(4-(((5-fluoro-2-methoxybenzoyl)amino)methyl)phenyl)-1-((1s)-2,2,2 …
Matched Iupac: … 5-amino-3-(4-{[(5-fluoro-2-methoxyphenyl)formamido]methyl}phenyl)-1-[(2S)-1,1,1-trifluoropropan-2-yl] …
Matched Description: … Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine ... Its high selectivity has been associated with lower discontinuation rates due to adverse events and a
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 326 - 350 of 6246 in total