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Displaying drugs 426 - 450 of 15137 in total

Hexocyclium

Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. It was once available under the tradename Tral marketed by Abbvie Inc. but has been discontinued. Proton pump inhibitors like DB00338 and opiate anti-diarrheal agents like DB00836 have largely replaced the...
Approved
Matched Description: … the use of anti-muscarinics in the treatment of gastric ulcers and diarrhea due to their more favorable ... Proton pump inhibitors like [DB00338] and opiate anti-diarrheal agents like [DB00836] have largely replaced …
Matched Categories: … Alimentary Tract and Metabolism …

Paspalum notatum pollen

Paspalum notatum pollen is the pollen of the Paspalum notatum plant. Paspalum notatum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Southeastern Grasses …

Phalaris arundinacea pollen

Phalaris arundinacea pollen is the pollen of the Phalaris arundinacea plant. Phalaris arundinacea pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Secale cereale pollen

Secale cereale pollen is the pollen of the Secale cereale plant. Secale cereale pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Vibrio cholerae Ogawa 50 classical biotype, formalin inactivated

Approved
Matched Mixtures name: … DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEA …

Gemeprost

Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy . It is not FDA-approved but available in...
Approved
Withdrawn
Matched Description: … It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone ... for termination of 1st- and 2nd-trimester pregnancy [A19726]. ... Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
Matched Categories: … Genito Urinary System and Sex Hormones …

Dyphylline

Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Description: … Dyphylline is a theophylline derivative with broncho- and vasodilator properties. ... It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. …
Matched Mixtures name: … Dyphylline and Guaifenesin …
Matched Categories: … Xanthines and Adrenergics ... diprophylline and adrenergics …

Calcium phosphate dihydrate

Approved
Matched Mixtures name: … NAVI Black and C-Clinic …

Nifedipine

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Mixtures name: … Seaford Nifedipine and Lidocaine Hydrochloride Cream …
Matched Categories: … atenolol and nifedipine ... nifedipine and diuretics ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers …

Didecyldimethylammonium

Approved
Experimental
Matched Mixtures name: … SANIVIR Hands, Body, and Surfaces Sanitizer ... KLEANMANN - Hand Sanitizer and Surface Disinfectant …
Matched Categories: … Antiseptics and Disinfectants …

Zaleplon

Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Description: … Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of …
Matched Categories: … gamma-Aminobutyric Acid A Receptor Agonist ... Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … [clotrimazole], due to its broad spectrum and good absorption. ... Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... Ketoconazole and its predecessor [clotrimazole] continue to be used in topical formulations. …
Matched Mixtures name: … Ketoconazole 2% / Salicylic Acid 2% …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …

Dichlorobenzyl alcohol

Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved
Matched Description: … with mouth and throat infections. ... Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated …
Matched Mixtures name: … STREPSILS HONEY AND LEMON ... STREPSILS SORE THROAT AND BLOCKED NOSE LOZENGE ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Iupac: … tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …

Moxidectin

Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Description: … ) with activity against nematodes, insects, and acari. ... Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites ... [A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June …
Matched Mixtures name: … Advocate Spot-on Solution for Small Cats and Ferrets …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …

Tenecteplase

Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids...
Approved
Matched Description: … It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine ... 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296- …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Safinamide

Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Description: … It was approved in Europe in February 2015, and in the United States on March 21, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Xanthan gum

Xanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic acid. Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by the FDA....
Approved
Matched Description: … The major constituents include D-glucose, D-mannose, and D-glucuronic acid. ... It is used as a thickening agent and stabilizer in emulsions. ... is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and …
Matched Categories: … Diet, Food, and Nutrition …

Chromium picolinate

Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate...
Approved
Matched Description: … It is a coordination complex consisting of chromium(III) and picolinic acid. ... Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. ... Chromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity …

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …

Ledipasvir

Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … and 3a of HCV. ... It is effective against genotypes 1a, 1b, 4a, and 5a and with a lesser activity against genotypes 2a ... count, and neuropsychiatric effects [A19635]. …
Matched Mixtures name: … Ledipasvir and Sofosbuvir …
Matched Categories: … sofosbuvir and ledipasvir …

Corynebacterium diphtheriae

Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … formaldehyde and diafiltered. ... The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and …
Matched Mixtures name: … Tetanus and Diphtheria Toxoids Adsorbed …

Denileukin diftitox

A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Description: … A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin ... fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier ... antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect, and ... water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and …
Matched Mixtures name: … Rohto Sun and Sport ... Redness reliever and Lubricant ... Meijer Advanced Redness and Irritation Relief …
Displaying drugs 426 - 450 of 15137 in total