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Displaying drugs 26 - 50 of 13041 in total
Cimetidine
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Salts cas: … 70059-30-2 …
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates ... MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Salts cas: … 70059-30-2 …
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates ... MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Povidone
Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Synonyms: … 1-vinyl-2-pyrrolidinone polymer ... 1-ethenyl-2-pyrrolidinone homopolymer …
Matched Mixtures name: … Murine Tears 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VIDISEPT 2% ... OCULOTECT FLUID % 5 STERIL GÖZ DAMLA, 10 ML ... PROTAGENT SE TEK DOZ GÖZ DAMLASI, 20 ADET …
Matched Mixtures name: … Murine Tears 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VIDISEPT 2% ... OCULOTECT FLUID % 5 STERIL GÖZ DAMLA, 10 ML ... PROTAGENT SE TEK DOZ GÖZ DAMLASI, 20 ADET …
Tiaprofenic acid
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … 2-(5-Benzyl-2-thienyl)propionsäure ... 2-(5-Benzoyl-thiophen-2-yl)-propionic acid ... 5-benzoyl-α-methyl-2-thiopheneacetic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … SURGAM 300 MG TABLET, 20 ADET ... SURGAM RETARD 300 MG TABLET, 20 ADET …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … SURGAM 300 MG TABLET, 20 ADET ... SURGAM RETARD 300 MG TABLET, 20 ADET …
Telmisartan
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid ... 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid ... 4'-[(1,4'-dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid …
Matched Iupac: … 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl ... ]-2-carboxylic acid …
Matched Description: … Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 …
Matched Salts cas: … 515815-47-1 …
Matched Mixtures name: … ทวินสตา 40/5 มก. ... ทวินสตา 80/5 มก. ... CARDIOCAPA 40/5 …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers …
Matched Products: … TELSTAN 20 TABLET 20 mg ... Actelsar 20 mg Tabletten ... RENANGIO® 20 …
Matched Iupac: … 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl ... ]-2-carboxylic acid …
Matched Description: … Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 …
Matched Salts cas: … 515815-47-1 …
Matched Mixtures name: … ทวินสตา 40/5 มก. ... ทวินสตา 80/5 มก. ... CARDIOCAPA 40/5 …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers …
Matched Products: … TELSTAN 20 TABLET 20 mg ... Actelsar 20 mg Tabletten ... RENANGIO® 20 …
Albendazole
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Synonyms: … 5-(propylthio)-2-carbomethoxyaminobenzimidazole ... O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate ... (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ANDAZOL 400 MG FILM KAPLI TABLET, 1 ADET ... ALBENDAZOL 400 MG/20 ML SUSPENSIÓN ... ANDAZOL 200 MG/10 ML SÜSPANSİYON, 20 ML …
Matched Iupac: … methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ANDAZOL 400 MG FILM KAPLI TABLET, 1 ADET ... ALBENDAZOL 400 MG/20 ML SUSPENSIÓN ... ANDAZOL 200 MG/10 ML SÜSPANSİYON, 20 ML …
Tolazoline
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Synonyms: … 2-Benzyl-2-imidazoline ... 2-Benzylimidazoline ... 2-Benzyl-4,5-imidazoline …
Matched Iupac: … 2-benzyl-4,5-dihydro-1H-imidazole …
Matched Salts cas: … 59-97-2 …
Matched Categories: … Peripheral alpha-1 blockers ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Matched Iupac: … 2-benzyl-4,5-dihydro-1H-imidazole …
Matched Salts cas: … 59-97-2 …
Matched Categories: … Peripheral alpha-1 blockers ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Rotigotine
Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Synonyms: … (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol …
Matched Iupac: … (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Salts cas: … 125572-93-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists …
Matched Products: … Rotigotin UCB 1 mg/24 Stunden transdermales Pflaster ... Rotigotin Luye 1 mg/24 Stunden transdermales Pflaster ... นิวโปร 2 มก./ 24 ชม. แผ่นปิดผิวหนัง …
Matched Iupac: … (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Salts cas: … 125572-93-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists …
Matched Products: … Rotigotin UCB 1 mg/24 Stunden transdermales Pflaster ... Rotigotin Luye 1 mg/24 Stunden transdermales Pflaster ... นิวโปร 2 มก./ 24 ชม. แผ่นปิดผิวหนัง …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Salts cas: … 612548-45-5 …
Matched Mixtures name: … ไตรเวอร์ราม 20 มก./5 มก./5 มก. ... Triveram 20 mg/5 mg/5 mg Filmtabletten ... ไตรเวอร์ราม 20 มก./10 มก./5 มก. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … COVERSYL ARGININE 5 MG ... อะเซอทิล อาร์จินีน 5 มก. ... COVERSYL 5 MG FILM TABLET, 30 ADET …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Salts cas: … 612548-45-5 …
Matched Mixtures name: … ไตรเวอร์ราม 20 มก./5 มก./5 มก. ... Triveram 20 mg/5 mg/5 mg Filmtabletten ... ไตรเวอร์ราม 20 มก./10 มก./5 มก. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … COVERSYL ARGININE 5 MG ... อะเซอทิล อาร์จินีน 5 มก. ... COVERSYL 5 MG FILM TABLET, 30 ADET …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … [2-(2-pyridyl)ethyl]methylamine ... 2-[2-(methylamino)ethyl]pyridine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately 5 …
Matched Salts cas: … 133206-34-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETARİS 24 MG TABLET, 20 ADET ... BETASERC 24 MG TABLET, 20 ADET …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately 5 …
Matched Salts cas: … 133206-34-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETARİS 24 MG TABLET, 20 ADET ... BETASERC 24 MG TABLET, 20 ADET …
Encainide
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide ... 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide ... (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Cedazuridine
Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such as decitabine and azacitidine are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous...
Approved
Investigational
Matched Synonyms: … (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine …
Matched Iupac: … (4R)-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (4R)-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine ... 4-(Bis(2-chloroethyl)amino)-L-phenylalanine ... 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Salts cas: … 3223-07-2 …
Matched Products: … İÇEREN FLAKON+1 ADET ÇÖZÜCÜ İÇEREN FLAKON ... อัลเคอแรน (เม็ด 2 มก.) ... ALKERAN® 2 MG TABLETAS …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Salts cas: … 3223-07-2 …
Matched Products: … İÇEREN FLAKON+1 ADET ÇÖZÜCÜ İÇEREN FLAKON ... อัลเคอแรน (เม็ด 2 มก.) ... ALKERAN® 2 MG TABLETAS …
Tetryzoline
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Synonyms: … 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline ... 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole ... (RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Description: … [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 …
Matched Salts cas: … 522-48-5 …
Matched Mixtures name: … EFEMOLINE 5 ML DAMLA …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Murine Plus 2 ... OPHTA OFT %0,05 5 ML DAMLA ... EYE-VISOL %0.05 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Description: … [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 …
Matched Salts cas: … 522-48-5 …
Matched Mixtures name: … EFEMOLINE 5 ML DAMLA …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Murine Plus 2 ... OPHTA OFT %0,05 5 ML DAMLA ... EYE-VISOL %0.05 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Eprosartan
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid ... (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid ... (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Iupac: … 4-({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic …
Matched Description: … It performs 2 actions on the renin angiotensin system. …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Matched Iupac: … 4-({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic …
Matched Description: … It performs 2 actions on the renin angiotensin system. …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Phenoxyethanol
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Synonyms: … 1-Hydroxy-2-phenoxyethane ... 2-phenoxyethanol ... 2-Phenoxyethyl alcohol …
Matched Iupac: … 2-phenoxyethan-1-ol …
Matched Mixtures name: … Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, Lösung ... FITO INTERTULLE, 5 ADET ... Linola sept 1 mg/g + 10 mg/g Wund-Gel …
Matched Iupac: … 2-phenoxyethan-1-ol …
Matched Mixtures name: … Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, Lösung ... FITO INTERTULLE, 5 ADET ... Linola sept 1 mg/g + 10 mg/g Wund-Gel …
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Synonyms: … (−)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine ... (−)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one ... (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] ... of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] ... of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Secnidazole
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2 ol ... 1-(2 hydroxypropyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SECNIZOL® 2 G ... SECNIDOX 1000 MG FILM TABLET,2 ADET ... SECNIDOX 500 MG FILM TABLET ,2 FILM TABLET …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SECNIZOL® 2 G ... SECNIDOX 1000 MG FILM TABLET,2 ADET ... SECNIDOX 500 MG FILM TABLET ,2 FILM TABLET …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … (−)-2-pyrrolidone-5-carboxylic acid ... 5-Pyrrolidone-2-carboxylic acid ... 5-oxo-2-pyrrolidinecarboxylic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MAG 2 ... Mag 2 Pwr 1.5gm/pck …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MAG 2 ... Mag 2 Pwr 1.5gm/pck …
Oxeladin
Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.
Approved
Withdrawn
Matched Synonyms: … 2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate …
Matched Iupac: … 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate …
Matched Salts cas: … 52432-72-1 …
Matched Iupac: … 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate …
Matched Salts cas: … 52432-72-1 …
Dasatinib
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 ... -thiazole-5-carboxamide …
Matched Iupac: … N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 ... -thiazole-5-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … LITEDA 20 MG ... Pharma 20 mg-Filmtabletten ... SPRYCEL (TABLETS 20 MG) …
Matched Iupac: … N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 ... -thiazole-5-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … LITEDA 20 MG ... Pharma 20 mg-Filmtabletten ... SPRYCEL (TABLETS 20 MG) …
Sulfathiazole
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … N(1)-2-Thiazolylsulfanilamide ... 2-Sulfonamidothiazole ... 2-Sulfanilamidothiazol …
Matched Iupac: … 4-amino-N-(1,3-thiazol-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 144-74-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-amino-N-(1,3-thiazol-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 144-74-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one ... 2',3'-Dideoxycytidine …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cefradine
A semi-synthetic cephalosporin antibiotic.
Approved
Matched Synonyms: … (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0) ... (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 ... oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Salts cas: … 75975-70-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … CEFRADINA 250 MG / 5 ML SUSPENSION ... VERACEF POLVO PARA SUSPENSIÓN ORAL250 MG/5 ML ... CEFRADINA 250 MG /5 ML POLVO PARA SUSPENSION …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Salts cas: … 75975-70-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … CEFRADINA 250 MG / 5 ML SUSPENSION ... VERACEF POLVO PARA SUSPENSIÓN ORAL250 MG/5 ML ... CEFRADINA 250 MG /5 ML POLVO PARA SUSPENSION …
Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Serdolect 20 mg - Filmtabletten ... SERDOLECT 20 MG FILM KAPLI TABLET, 28 ADET …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Serdolect 20 mg - Filmtabletten ... SERDOLECT 20 MG FILM KAPLI TABLET, 28 ADET …
Balsalazide
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … 3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid ... (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. ... Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. ... Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. …
Matched Categories: … Non COX-2 selective NSAIDS …
Displaying drugs 26 - 50 of 13041 in total