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Displaying drugs 601 - 625 of 15366 in total

Cinnamyl alcohol

Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as DB14184 within commercial products. Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity...
Approved
Experimental
Matched Description: … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266 ... Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as [DB14184] within commercial ... Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging ... (non-reversible defects); and 2) evaluating myocardial function and developing information for use in ... Currently available within a preparation kit for injection, Technetium Tc 99m Sestamibi is indicated …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant ... When in complex with iodine, [DB06812] displays antiseptic properties where the iodine, a bactericidal ... a few clinical studies that the application of the compound in wounds was associated with impaired wound …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Gallium Ga-68 gozetotide

Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Iupac: … carbamoyl]ethyl}-2-hydroxyphenyl)methyl](carboxylatomethyl)amino}ethyl)(carboxylatomethyl)amino]methyl}-4- …
Matched Description: … [L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate ... [L43542] In December of the same year, the drug was fully authorized by the EMA. ... [A225396] In nearly all prostate cancers, malignant cells express a transmembrane protein called prostate-specific …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Perflutren

Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the...
Approved
Matched Description: … Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated ... level of contrast visible in the resulting ultrasound image. ... The difference in density between the gas-filled bubbles and the blood around them creates an increased …
Matched Mixtures name: … Optison Perflutren Protein-Type A Microspheres …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Almotriptan

Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, ... Almotriptan is in a class of medications called selective serotonin receptor agonists. ... Almotriptan is a triptan drug for the treatment of migraine headaches. …
Matched Categories: … Monoamine Oxidase A Substrates …

Technetium Tc-99m disofenin

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Description: … It is available as an intravenous injection in a preparation kit under the name Hepatolite. ... Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic ... quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Description: … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 ... It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation …
Matched Categories: … Monoamine Oxidase A Substrates …

Colchicine

Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Description: … [A183611] Its use was first approved by the FDA in 1961. ... Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum ... [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602] …

Pentoxyverine

Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The...
Approved
Investigational
Withdrawn
Matched Description: … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and ... Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic …
Matched Mixtures name: … Pancold A …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Description: … Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin ... It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …

Trypan blue free acid

Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … [1,1'-biphenyl]-4-yl}diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonic acid ... 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- …
Matched Description: … Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence ... of a mature cataract. ... This is done to aid in visualization before creating the continuous curvilinear capsulorhexis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

D-alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, ... 10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males ... who may demonstrate a genuine deficiency in vitamin E. …
Matched Mixtures name: … Vitamin A C E W.niacinam.beta Car.and Min. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … as a highly selective potassium removing agent. ... onset of action was approximately 1.0 hour and the median time to achieving normal potassium levels in ... Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Anethole

Approved
Experimental
Matched Iupac: … 1-methoxy-4-[(1E)-prop-1-en-1-yl]benzene …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tromethamine

An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Matched Description: … It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for ... cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Cetuximab

Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... [A227963] EGFR is often mutated in certain types of cancer and serves as a driver of tumorigenesis. ... [A227973] EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour …

Peanut oil

Peanut oil is derived from Arachis hypogaea which can be found in South America, Mexico, and Centro America. The kernels are consumed roasted but a large percentage is used for the production of vegetable oil. The peanut oil represents about 45-52% of the kernel content and it is mainly formed...
Approved
Matched Description: … The kernels are consumed roasted but a large percentage is used for the production of vegetable oil. ... Peanut oil is derived from _Arachis hypogaea_ which can be found in South America, Mexico, and Centro ... [A33169] Under the FDA, peanut oil is categorized as an approved inactive ingredient for its use in …

Aureobasidium pullulans var. pullutans

Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. Aureobasidium pullulans var. pullutans extract is used in allergenic testing.
Approved
Matched Description: … Aureobasidium pullulans var. pullutans extract is used in allergenic testing. ... Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … A Mold Mixture ... A Mold Mixture ... A Mold Mixture …

Molybdenum

Molybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in...
Approved
Matched Description: … As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation ... It is an essential trace dietary element and acts as a critical cofactor in several molybdenum-dependent ... When complexed with Technetium Tc 99m, molybdenum is used as a radiopharmaceutical agent in diagonistic …
Matched Mixtures name: … Extra Once A Day ... Maximum Once A Day ... ONE A DAY TABLET …

Fenoprofen

An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved

Danaparoid

Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and DB09301 , and they are isolated from the porcine intestinal mucosa [FDA Label]. Danaparoid possesses a potent antithrombic activity that works by inhibiting...
Approved
Withdrawn
Matched Description: … on August 14, 2002, due to a shortage in drug substance by the manufacturer. ... Danaparoid possesses a potent antithrombic activity that works by inhibiting activated factor X (Factor ... of a mixture of glycosaminoglycans [A32565]. …

Racemethionine

A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Approved
Experimental
Matched Iupac: … 2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. …
Matched Mixtures name: … Extra Once A Day ... A/o-26 - Caplet ... Maximum Once A Day …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, ... arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in ... [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes …
Matched Salts cas: … 152-11-4 …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …

Sutimlimab

Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … [A245144] Hemolysis in patients with CAD is driven by complement activation, which initiates a cascade ... [L40114,A245144] Sutimlimab was also approved by the European Commission in November 2022.[L44116] ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies …
Displaying drugs 601 - 625 of 15366 in total