Displaying drugs 751 - 775 of 1197 in total
Sildenafil
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... muscle relaxation and vasodilation that subsequently facilitates relief in pulmonary arterial hypertension …
Matched Products: … SILER ... SILDE 1A PHARMA PAH 20MG ... Silde – 1A Pharma 100 mg Tabletten …
Matched Products: … SILER ... SILDE 1A PHARMA PAH 20MG ... Silde – 1A Pharma 100 mg Tabletten …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Description: … regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Davimet with Iron ... Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin …
Matched Salts name: … Levomefolate calcium ... Levomefolate magnesium …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Folic Acid and Derivatives …
Matched Products: … L-Methylfolate Calcium …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Davimet with Iron ... Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin …
Matched Salts name: … Levomefolate calcium ... Levomefolate magnesium …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Folic Acid and Derivatives …
Matched Products: … L-Methylfolate Calcium …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate …
Matched Iupac: … oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate …
Matched Categories: … Amprenavir and Prodrugs …
Matched Iupac: … oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate …
Matched Categories: … Amprenavir and Prodrugs …
Oxibendazole
Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Investigational
Vet approved
Matched Synonyms: … Methyl 5-n-propoxy-2-benzimidazole carbamate …
Matched Iupac: … methyl N-(6-propoxy-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Iupac: … methyl N-(6-propoxy-1H-1,3-benzodiazol-2-yl)carbamate …
Colestilan chloride
Colestilan is an ingredient in the EMA-withdrawn product BindRen.
Approved
Investigational
Withdrawn
Matched Synonyms: … Colestilan chloride …
Matched Name: … Colestilan chloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Name: … Colestilan chloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Acetazolamide
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched International brands: … Acetak …
Matched Description: … gradient, increased chloride current, and increased inhibition. ... (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ACETA DIAZOL …
Matched Description: … gradient, increased chloride current, and increased inhibition. ... (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ACETA DIAZOL …
Oseltamivir
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Description: … (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and ... that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce ... prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. …
Matched Salts name: … Oseltamivir phosphate …
Matched Categories: … Acetates …
Matched Products: … Oseltamivir Phosphate ... Oseltamavir Phosphate ... Oseltamivir phosphate …
Matched Salts name: … Oseltamivir phosphate …
Matched Categories: … Acetates …
Matched Products: … Oseltamivir Phosphate ... Oseltamavir Phosphate ... Oseltamivir phosphate …
Pralidoxime
Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Description: … Pralidoxime is an antidote to organophosphate pesticides and chemicals. ... bond formed between the organophosphate and acetylcholinesterase. ... hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester …
Matched Mixtures name: … ATNAA atropine and pralidoxime chloride Auto-Injector …
Matched Salts name: … Pralidoxime chloride …
Matched Categories: … pralidoxime and atropine …
Matched Products: … Protopam Chloride ... Pralidoxime Chloride ... Protopam Chloride Inj 1gm …
Matched Mixtures name: … ATNAA atropine and pralidoxime chloride Auto-Injector …
Matched Salts name: … Pralidoxime chloride …
Matched Categories: … pralidoxime and atropine …
Matched Products: … Protopam Chloride ... Pralidoxime Chloride ... Protopam Chloride Inj 1gm …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IROTEN 40 MG/2 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IROTEN 100 MG/5 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IROTEN 500 MG/25 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IROTEN 40 MG/2 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IROTEN 100 MG/5 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IROTEN 500 MG/25 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET …
Acamprosate
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Description: … Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and ... It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] …
Matched Salts name: … Acamprosate calcium …
Matched Products: … Acamprosate Calcium …
Matched Salts name: … Acamprosate calcium …
Matched Products: … Acamprosate Calcium …
Primaquine
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Description: … An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale ... Adverse effects include anemias and GI disturbances. …
Matched Salts name: … Primaquine phosphate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Primaquine Phosphate ... PRIMAQUINE PHOSPHATE …
Matched Salts name: … Primaquine phosphate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Primaquine Phosphate ... PRIMAQUINE PHOSPHATE …
Ethyl Oxo(Piperidin-1-Yl)Acetate
Experimental
Matched Name: … Ethyl Oxo(Piperidin-1-Yl)Acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Almasilate
Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However its therapeutic efficacy is not comparable to other approved antacids, as it is no more...
Approved
Experimental
Matched Synonyms: … Magnesium aluminosilicate hydrate …
Matched Iupac: … dialuminium(3+) ion magnesium(2+) ion hydrate disilicate …
Matched Description: … It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by ... Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. ... efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and …
Matched Categories: … Aluminum and magnesium containing antacids ... Alimentary Tract and Metabolism ... Silicon Compounds …
Matched Iupac: … dialuminium(3+) ion magnesium(2+) ion hydrate disilicate …
Matched Description: … It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by ... Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. ... efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and …
Matched Categories: … Aluminum and magnesium containing antacids ... Alimentary Tract and Metabolism ... Silicon Compounds …
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Salts name: … Dexamethasone phosphate ... Dexamethasone sodium phosphate …
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... dexamethasone and antibiotics …
Matched Products: … Hexadrol Phosphate ... DEXAMETHASONE Sodium Phosphate ... Dexamethasone Sodium Phosphate …
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Salts name: … Dexamethasone phosphate ... Dexamethasone sodium phosphate …
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... dexamethasone and antibiotics …
Matched Products: … Hexadrol Phosphate ... DEXAMETHASONE Sodium Phosphate ... Dexamethasone Sodium Phosphate …
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... PGs contribute to inflammation and pain signalling. …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac potassium …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... diclofenac and antiinfectives ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac potassium …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... diclofenac and antiinfectives ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM …
Ethyl chloride
Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the treatment of cellulose to make ethylcellulose for...
Approved
Experimental
Investigational
Matched Synonyms: … Ethyl chloride …
Matched Name: … Ethyl chloride …
Matched Description: … Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. ... Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp. …
Matched Categories: … ethyl chloride …
Matched Products: … ETHYL CHLORIDE …
Matched Name: … Ethyl chloride …
Matched Description: … Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. ... Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp. …
Matched Categories: … ethyl chloride …
Matched Products: … ETHYL CHLORIDE …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Description: … Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. ... corticosteroid and estrogen therapy. ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. ... corticosteroid and estrogen therapy. ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Hemin
Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.
Approved
Investigational
Matched Synonyms: … chloro(protoporphyrinato)iron(III) …
Matched Description: … More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand ... Hemin (trade name Panhematin) is an iron-containing porphyrin. …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand ... Hemin (trade name Panhematin) is an iron-containing porphyrin. …
Matched Categories: … Blood and Blood Forming Organs …
Selenic acid
Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of DB11135, an essential trace mineral for human health.
Approved
Matched Name: … Selenic acid …
Matched Iupac: … selenic acid …
Matched Description: … Selenic acid is an organic compound with the chemical formula H2SeO4. …
Matched Mixtures name: … Beta A With Vitamins C and E Plus Selenium ... One Daily Vitamin and Mineral Dietary Supplement ... Prenatal and Post Partum Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Selenium Compounds …
Matched Iupac: … selenic acid …
Matched Description: … Selenic acid is an organic compound with the chemical formula H2SeO4. …
Matched Mixtures name: … Beta A With Vitamins C and E Plus Selenium ... One Daily Vitamin and Mineral Dietary Supplement ... Prenatal and Post Partum Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Selenium Compounds …
Tubocurarine
Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera Chondrodendron and Strychnos....
Approved
Matched Description: … Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid ... number of plant-derived alkaloids, including [morphine] and [papaverine]. ... describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and …
Matched Salts name: … Tubocurarine chloride pentahydrate …
Matched Products: … Tubocurarine Chloride Inj 3mg/ml ... Tubocurarine Chloride Inj 3mg/ml USP …
Matched Salts name: … Tubocurarine chloride pentahydrate …
Matched Products: … Tubocurarine Chloride Inj 3mg/ml ... Tubocurarine Chloride Inj 3mg/ml USP …
Calcium fluoride
Experimental
Matched Name: … Calcium fluoride …
Matched Categories: … Calcium Compounds …
Matched Categories: … Calcium Compounds …
Salophen iron chelate
Experimental
Matched Name: … Salophen iron chelate …
Matched Iupac: … lambda4-iron(4+) 2-[(E)-({2-[(E)-[(2-oxidophenyl)methylidene]amino]phenyl}imino)methyl]benzen-1-olate …
Matched Iupac: … lambda4-iron(4+) 2-[(E)-({2-[(E)-[(2-oxidophenyl)methylidene]amino]phenyl}imino)methyl]benzen-1-olate …
Displaying drugs 751 - 775 of 1197 in total