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Displaying drugs 76 - 100 of 10666 in total

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … It is used in a number of health and beauty products including hair care products such as shampoo, conditioner ... , leave-in conditioner, and de-tangling products. ... Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical …
Matched Mixtures name: … QYO QYO Tangerine Bright Moist All In One Cream ... The Bamboo Of Damyang Moisture Essence ... Childrens Mylicon All in One Tummy Relief for Kids …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … The Bamboo Of Damyang Moisture ... The Bamboo Of Damyang Moisture Eye ... BK Cell 5DAYS OF SECRET LOVE TOTAL ANTI AGING …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Synonyms: … Activated 7-dehydrocholesterol …
Matched Description: … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there ... Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin ... Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … YUMUŞAK KAPSÜL, 7 ADET ... YUMUŞAK KAPSÜL , 7 KAPSÜL …

Anthrax vaccine

Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Description: … of Bacillus anthracis which are grown in a chemically defined protein-free medium. ... [L47526] It is considered one of the most likely agents to be used in a biological attack. ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high …

Tyrothricin

Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Description: … This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely ... of the six predominant tyrocidines, TrcA/A1, TrcB/B1, TrcC/C1, and other more minor contributors) and ... microbial resistance during the over 60 years of therapeutic use the complex has provided [A36360]. …

Ensulizole

Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... treatment provided protection against cyclobutane pyrimidine dimers and photosensitized the formation of ... According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations …
Matched Mixtures name: … Olay Total Effects 7-IN-1 Anti-aging Uv Moisturizer Plus Touch Of Foundation ... Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Description: … 25% of the mixture. ... Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride …

Saxagliptin

Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Description: … -4 (DPP-4) inhibitor class of drugs. ... Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase …
Matched Salts cas: … 709031-78-7 …
Matched Categories: … Drugs Used in Diabetes …

Abatacept

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … It is produced through recombinant DNA technology in mammalian CHO cells. ... 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. ... formulation of CTLA4-Ig into clinical trials (RG2077). …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …

Oftasceine

Oftasceine is also referred to as Fluorexon. It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. It is a fluorescent dye or luminescent agent.
Approved
Matched Iupac: … 2-{[(7'-{[bis(carboxymethyl)amino]methyl}-3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]- …
Matched Description: … It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate ... which is the hippuric acid salt of methenamine). …
Matched Mixtures name: … All-In-One UTI Emergency Kit …

Delandistrogene moxeparvovec

Delandistrogene moxeparvovec is an adeno-associated virus vector-based gene therapy developed by Sarepta Therapeutics. It was granted accelerated approval by the FDA on June 22, 2023, as the first gene therapy to treat Duchenne Muscular Dystrophy (DMD). DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading...
Approved
Investigational
Matched Description: … [L47026] DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading ... to a deficiency in functional dystrophin protein. ... [A260256] DMD tends to be more prevalent in males. …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... of heart contractions. ... It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

Finafloxacin

Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro …
Matched Iupac: … 7-[(4aS,7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline …
Matched Description: … Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ... Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December …

Chlorquinaldol

Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Description: … [F4549] It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa ... approved by the European Medicines Agency as a combination tablet with promestriene for the treatment of …

Cefradine

A semi-synthetic cephalosporin antibiotic.
Approved
Matched Synonyms: … 7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacid ... (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0) ... (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 …

Imipenem

Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Synonyms: … (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene ... (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2 ... (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene- …
Matched Iupac: … (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo …
Matched Description: … Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative ... [A15389] Imipenem is commonly used in combination with [cilastatin] and is now available in a triple-drug ... Imipenem was first approved by the FDA in November 1985 as the combination product Primaxin marketed …

Cefmetazole

A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Approved
Investigational
Matched Synonyms: … (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl …
Matched Iupac: … (6R,7S)-7-{2-[(cyanomethyl)sulfanyl]acetamido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl …
Matched Description: … It has a high rate of efficacy in many types of infection and to date no severe side effects have been ... A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and …

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …

Octreotide

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. ... hormone, somatostatin, which inhibits the secretion of growth hormone. …
Matched Products: … Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,5 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,05 mg/ml Injektionslösung in einer Fertigspritze …

Dyphylline

Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Synonyms: … (±)-7-(2,3-dihydroxypropyl)theophylline ... 7-(2,3-dihydroxypropyl)theophylline ... 7-(β,γ-dihydroxypropyl)theophylline …
Matched Iupac: … 7-(2,3-dihydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. …
Matched Categories: … combinations of xanthines …

Cefoxitin

Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0 …
Matched Iupac: … (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0 …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … formation of thrombus. ... Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the ... Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension ... , was discontinued in 2021. …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Description: … resistance through activating mutations in the EGFR gene. ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations ... [A7928] Development of third-generation EGFR-TKIs, such as osimertinib, has been in response to altered …

Lomifylline

Approved
Matched Synonyms: … 7-(5-oxohexyl)theophylline …
Matched Iupac: … 1,3-dimethyl-7-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Categories: … combinations of xanthines …
Displaying drugs 76 - 100 of 10666 in total