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Displaying drugs 76 - 100 of 9612 in total

Artesunate

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. ... Artesunate is indicated for the initial treatment of severe malaria. …
Matched Products: … PLASMOTRIM (R) 50 LACTAB (R) ... PLASMOTRIM(R) 200. RECTOCAPS(R) …

Niacin

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer ... potency than the R-enantiomer, but is metabolized at a higher rate. ... [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes …
Matched Products: … ISOPTIN (R) …

Rilonacept

Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... linked to the Fc portion of immunoglobulin G1. ... Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as …

Corifollitropin alfa

Corifollitropin alfa, also known as Elonva is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. This drug used together with a gonadotropin-releasing hormone (GnRH) antagonist, a type of medicine also used in fertility treatments. Elonva...
Approved
Investigational
Matched Description: … risk of ovarian hyperstimulation in the high responder study group of women [L2276], [A32526]. ... effectiveness of this drug, however, warns at the same time against the possibility of an increased ... In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … GONAL-F ® 300 UI (22 MCG)/0.5 ML INYECTOR (FOLITROPINA ALFA (R-HFSH)) …

Hyaluronic acid

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … the appearance of wrinkles and aging-related skin imperfections. ... [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in ... A popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Products: … วิสลูป (R) ... OSTENIL(R) MINI ... ADANT (R) DISPO …

Barium sulfate

Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Description: … and high level of clearance from the body [FDA label]. ... Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility ... Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … R-X 1 G/ML SÜSPANSİYON ... R-X KOLON 960 ML SUSPANSIYON ... R-X SUSPANSIYON % 100 240 ML …

Eplerenone

Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Iupac: … methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo …
Matched Description: … the negative regulatory feedback of aldosterone on renin secretion. ... shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of ... resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … RENVELA(R) TABLETS …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Mixtures name: … Formula R Tab ... Central-vite 18 Essential ... Herbs of Gold B Complex Plus Softgel …
Matched Products: … ไฮซี(R) 100 ... ไฮซี (R)100 สวีทเลทส์ ... R-CORBACID 100 MG / 1ML SOLUCION INYECTABLE …

Iron sucrose

Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … เฟอโรเจน(R) …

Difenoxin

Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Description: … with atropine in the brand mixture Lomotil(R). ... Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. ... However, the antidiarrheal potency of difenoxin is much greater than its CNS effects, which makes it …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of ... treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of ... [A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced …
Matched Categories: … combinations of xanthines …
Matched Products: … PERIVAX - R 400 MG TABLETAS …

Clonazepam

A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.[FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being...
Approved
Illicit
Matched Description: … of gamma-aminobutyric acid receptor responses. ... [FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement ... Now available as a generic medication, the agent continues to see exceptionally high use as millions of …
Matched Products: … Clonazepam-R ... PMS-clonazepam-R ... PHL-clonazepam-R …

Alfacalcidol

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … mechanism regulates the final activation step of vitamin D in the kidneys. ... Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of ... The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … ONE - ALPHA (R) (0.5 MCG) …

Regadenoson

Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Products: … Lexiscan(r) (regadenoson) …

Beremagene geperpavec

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Description: … Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of ... DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component of ... A259771] Beremagene geperpavec is genetically modified to deliver _COL7A1_, thereby restoring the levels of …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Ripretinib

Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as sunitinib and imatinib. Ripretinib, also known as Qinlock, is manufactured by Deciphera Pharmaceuticals and was initially approved by the FDA on May 15, 2020....
Approved
Matched Description: … treatment with a minimum of 3 other kinase inhibitors. ... Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST ... [L13769] It is the first drug approved as a fourth-line therapy in the specific setting of prior …

Rabies virus inactivated antigen, A

Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Products: … RABIPUR(R) …

Human papillomavirus type 11 L1 capsid protein antigen

Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Description: … of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant *Saccharomyces ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …

Thyrotropin alfa

Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … The alpha subunit of thyrotropin alfa, which is the effector region responsible for the stimulation of ... of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues ... The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating …
Matched Products: … THYROGEN(R) …

Cefixime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … a family of enzymes known as "penicillin-binding proteins" (PBPs). ... A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of ... glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Its pharmacological action mimics the biological activity of endogenous LH; an acute rise of LH, or LH ... use in the stimulation of follicular development. ... It is a heterodimeric glycoprotein made up of monomeric units. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Choriogonadotropin alfa

Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Description: … The primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Valdecoxib

Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Approved
Investigational
Withdrawn
Matched Description: … ., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke …
Matched Categories: … combinations of sulfonamides …
Matched Products: … BEXTRA (R) 40 MG TABLETAS RECUBIERTAS …
Displaying drugs 76 - 100 of 9612 in total