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Displaying drugs 1126 - 1150 of 1507 in total

Artesunate

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … Artesunate is indicated for the initial treatment of severe malaria. ... [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. ... [L14099] The World Health Organization recommends artesunate as first line treatment for severe malaria …
Matched Salts name: … Artesunate sodium …
Matched Categories: … Artemisinin and derivatives ... artesunate and mefloquine ... artesunate and amodiaquine ... artesunate and pyronaridine ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … ARTESUNATE FOR INJECTION ... ARTESUN POWDER FOR INJECTION 60 MG …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Dicloxacillin Sodium …

Vinflunine

Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death...
Approved
Investigational
Matched Description: … , [DB00570], and [DB00541] [A31975]. ... Vinflunine ditartrate is an active ingredient in the EMA-authorised product Javlor for intravenous infusion ... vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Javlor Concentrate for Solution for Infusion 25 mg/mL …

Pentamidine

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Description: … Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in ... It may cause diabetes mellitus, central nervous system damage, and other toxic effects. …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents ... Antibiotics for Pneumocystis Pneumonia ... Medications that reduce magnesium levels …
Matched Products: … Pentamidine Isetionate for Injection BP ... DBL™ PENTAMIDINE ISETHIONATE FOR INJECTION BP 300mg ... DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial …

Choriogonadotropin alfa

Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Description: … O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER ... -121, SER-127, SER-132 and SER-138 (on beta subunit). ... human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Ovidrel Solution for Injection 250 mcg ... OVIDREL 250MCG/0.5ML SOLUTION FOR INJECTION …

(10R)-10-formyl-5,8,10-trideazafolic acid

Experimental
Matched Name: … (10R)-10-formyl-5,8,10-trideazafolic acid …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Description: … In 2006, the FDA reintroduced the drug to the market for multiple sclerosis. ... [A261326] Natalizumab was further approved by the FDA for the treatment of Crohn's Disease in January …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Tysabri Concentrate for Solution for Infusion 300mg/15ml …

Idursulfase

Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … ELAPRASE SOLUTION FOR INTRAVENOUS INFUSION ... Elaprase (TM) Solution for Intravenous Infusion 2mg/ ml …

Antithymocyte immunoglobulin (rabbit)

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Description: … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Thymoglobuline 5mg/ml Powder for concentrate for solution for infusion …

Bemiparin

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … tumors and diabetic foot ulcers [L1468, A7866]. ... Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins ... These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and …
Matched Salts name: … Bemiparin sodium …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … HIBOR 2,500 IU ANTI XA/0.2ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES ... HIBOR 10,000 IU ANTI XA/0.4 ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES ... HIBOR 3,500 IU ANTI XA/0.2 ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES …

Busulfan

Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion ... Busulfan for Injection ... CANBUSUL- Busulfan Injection 6 mg/ml Concentrate for Solution for Infusion …

Lurbinectedin

Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma, chronic lymphocytic leukemia (CLL), breast cancer, and small-cell lung cancer (SCLC). It is a derivative of the marine-derived agent ecteinascidin (trabectedin), an anticancer agent found in extracts of the tunicate...
Approved
Investigational
Matched Description: … including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer,[A214322] and ... [L14336] This accelerated approval is based on the rate and duration of therapeutic response observed ... in ongoing clinical trials and is contingent on the verification of these results in confirmatory trials …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ZEPZELCA POWDER FOR SOLUTION FOR INFUSION 4MG/VIAL …

Chondroitin sulfate

Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA). The SYSADOA status suggested a pain relief and increased joint mobility after a relative long regular administration, as well as a long-lasting effect after the end of the treatment. Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine...
Approved
Investigational
Nutraceutical
Matched Description: … [A7906] The SYSADOA status suggested a pain relief and increased joint mobility after a relative long ... Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis ... Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic …
Matched Mixtures name: … Blackmores Joint Formula with Glucosamine and Chondroitin ... CARTICAP FOR ... Cosamine Plus Forte M Powder …
Matched Salts name: … Chondroitin sulfate sodium (bovine) ... Chondroitin sulfate sodium (shark) ... Chondroitin sulfate sodium (chicken) ... Chondroitin sulfate sodium (porcine) …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … HIRUDOID FORT %0,445 JEL, 40 G ... HIRUDOID FORT %0,445 KREM, 40 G …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing ... 1 and Type 2 Diabetes. ... and proteolysis. …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … solution for Injection in vial 100 Units/ml ... Glaritus 100 IU/mL Solution for injection ... BASALOG 100 IU/mL, SOLUTION FOR INJECTION IN A VIAL …

Pegfilgrastim

Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … pharmacokinetic profile and conditions of use. ... Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF ... [A187601] The drug is approved for use to decrease the incidence of infection, as manifested by febrile …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL ... Filpegla 6 mg / 0.6 mL Solution for Injection in Pre-filled Syringe …

Blinatumomab

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Matched Description: … promotes tumor cell lysis and apoptosis. ... acute lymphoblastic leukemia (ALL) in relapsed and refractory patients. ... recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BLINCYTO POWDER FOR INFUSION 35 MCG/VIAL ... BLINCYTO (Blinatumomab) for injection 35 mcg/vial …

Methoxy polyethylene glycol-epoetin beta

Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Mircera Solution for Injection 100mcg/0.3ml (Pre-filled Syringe) ... Mircera Solution for Injection 75mcg/0.3ml (Pre-filled Syringe) ... Mircera Solution for Injection 50mcg/0.3ml (Pre-filled Syringe) …

Sulfur hexafluoride

Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric...
Approved
Matched Description: … of focal liver lesions in adult and pediatric patients ... the left ventricular chamber and to improve the delineation of the left ventricular endocardial border ... Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify …
Matched Products: … SONOVUE POWDER FOR DISPERSION FOR INJECTION 8 microlitres/ml …

Terlipressin

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … GLYPRESSIN FOR INJECTION 1 mg/vial ... GLYPRESSIN 1mg/8.5ml solution for injection ... GLYPRESSIN solution for injection, 1 mg/8.5 ml …

Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.
Approved
Matched Description: … copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi ... Stamicis Kit for Radiopharmaceutical Preparation 1mg ... STAMICIS 1 mg Kit for Radiopharmaceutical Preparation …

Imiglucerase

Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated...
Approved
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … (Imiglucerase) 400U Powder for solution for injection …

Satralizumab

Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Description: … [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... [eculizumab] in June 2019 and [inebilizumab] in June 2020). ... interleukin-6 (IL-6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML ... ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe …

Radium Ra 223 dichloride

Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. It was...
Approved
Investigational
Matched Description: … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas ... It was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which ... indicated in patients who have metastatic bone cancer that is symptomatic with no visceral metastases and …
Matched Products: … XOFIGO SOLUTION FOR INJECTION 1100kBq/ML ... Xofigo (Radium-223 Dichloride) 1100 kBq/mL Solution for Injection …

Lanreotide

Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. Lanreotide is manufactured by the company, Ipsen...
Approved
Matched Description: … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed ... It is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. ... Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg ... Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 60 mg ... Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 90 mg …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Description: … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic ... Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. ... therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and …
Matched Products: … INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 75mg/0.75ml …
Displaying drugs 1126 - 1150 of 1507 in total