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Displaying drugs 101 - 125 of 633 in total

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …

Von Willebrand factor human

The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … and hemophilia A. ... vessel injury and stabilizing procoagulant factor VIII (FVIII). ... It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

OTL-203

OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …

OTL-102

OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … plaque and reducing gingivitis. ... found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and ... In these products, it generally mediates an antiseptic activity and protective action against dental …
Matched Mixtures name: … QCare Oral Cleansing and Suctioning System, Q4 ... QCare Rx Oral Cleansing and Suctioning System ... QCare Rx Oral Cleansing and Suctioning System …
Matched Categories: … Antiseptics and Disinfectants ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Mouthwashes and Gargles …
Matched Products: … SmartMouth Gum and Plaque Formula ... Qcare Oral Cleansing and Suctioning System ... Crest Pro-Health Gum and Breath Purify …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and …
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... BENZOCAINE and RESORCINOL ... BENZOCAINE and RESORCINOL …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Sting and Bite ... Bite and Sting relief ... Medicaine Sting and Bite …

Ginseng

Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.
Investigational
Nutraceutical
Matched Synonyms: … Insam root ... Ninjin root ... Hong shen root …
Matched Description: … resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and …
Matched Mixtures name: … Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals. …
Matched Categories: … Herbs and Natural Products …
Matched Products: … Power / Vacsu Power (Dynamic and Powerful 99 year life) ... Stem Cell Extract of wild mountain ginseng ... Niwedah Shilajit Ashwagandha Rhodiola Rosea Panaxginseng …

Indocyanine green acid form

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Products: … Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint ... Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and Pinpoint …

Chenopodium album pollen

Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …

Taniraleucel

Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, ... Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. …

Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …

Panthenol

Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair ... Ceracos The Black …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … BABOR Baborganic Calm and Relax ... Black Head Remover ... Roota Re V Tonic …

Guaifenesin

Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … over-the-counter cough and cold products and is currently a widely available over-the-counter generic ... Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and ... continues to be one of very few - if not perhaps the only drug that is readily available and used as …
Matched Mixtures name: … Topco tussin cf max ... Day Time Cold Multi-Symptom Cool Blast ... Premier Value Chest Congestion and cough releif DM …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Topco Mucus Relief ... Up and Up Mucus Relief ... Up and Up Childrens Mucus Relief …

Viagenpumatucel-L

Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine …

TN-201

TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
Matched Synonyms: … Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …

Undecylenic acid

Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Description: … relieves itching, burning, and irritation associated with the skin condition. ... isolated from the products of distillation of castor oil in 1877 via pyrolysis of ricinoleic acid, and ... undecylenate is an example of a topical antifungal agent that treats skin infections such as athlete’s foot and …
Matched Mixtures name: … Fungi Nail Toe and Foot MS ... Fungi Nail Toe and Foot MS ... Foot and Body Powder …
Matched Products: … Fungi Nail Toe and Foot ... Fungi Nail Toe and Foot Pen ... Hongo Killer Nail and Fungus …

Plantago seed

Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied . Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Name: … Plantago seed …
Matched Description: … It is found in some laxatives for treating occasional constipation and restoring regularity in bowel ... Platango seeds refer to the seeds collected from various species of plantago trees. …
Matched Categories: … Herbs and Natural Products …
Matched Products: … Psyllium Seed Blond 630mg ... Up and Up Fiber Therapy ... up and up fiber therapy Natural Fiber …

Atacicept

Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …

Trolamine salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and ... It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin …
Matched Products: … Blue-Emu Ultra with Hemp Seed ... Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and …
Matched Mixtures name: … STEP-OUT ... Top Care Flu and Sore Throat ... Topco tussin cf max …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac …
Matched Products: … CareOne Cold and Sinus ... Up and Up Sinus PE ... Up and Up nasal decongestant PE …

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … Target Up and Up 3 Step Acne System ... Target Up and Up 3 Step Acne System ... Meijer 3 Step Acne System …
Matched Products: … Panoxyl Wash 10 - Liq Top 10% ... Panoxyl Aquagel 20 - Gel Top 20% ... Rodan and Fields Unblemish - Acne Medicated …
Displaying drugs 101 - 125 of 633 in total