Displaying drugs 101 - 125 of 2696 in total
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) …
Menadione
A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Categories: … Cytochrome P-450 CYP1A2 Inducers (strength unknown) ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2A6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) …
Acetyl sulfisoxazole
Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog …
Pyrazinamide
A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and...
Approved
Vet approved
Telotristat ethyl
Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.[A252937, A252942]...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP2B6 Inducers (strength unknown) ... Cytochrome P-450 CYP2C19 inhibitors (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) …
Hydrocortisone butyrate
Approved
Vet approved
Matched Categories: … Cytochrome P-450 CYP2C8 Inducers (strength unknown) ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) …
Pancuronium
A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Approved
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Magnesium oxide
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Matched Mixtures name: … Multivitamins W Minerals Extra Strength ... Aspirin Plus Stomach Guard Extra Strength ... Aspirin With Stomach Guard Extra Strength - Tab …
Allantoin
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Mixtures name: … Orajel for Cold Sores Maximum Strength ... Terrasil Burn Care and Relief maximum strength ... Terrasil Itch, Rash and Pain Relief Maximum Strength …
Ipratropium
Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Encorafenib
Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP2B6 Inducers (strength unknown) ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C9 Inducers (strength unknown) ... Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) …
Isavuconazonium
Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP2B6 Inducers (strength unknown) ... Cytochrome P-450 CYP2C8 Inducers (strength unknown) ... Cytochrome P-450 CYP2C9 Inducers (strength unknown) ... Cytochrome P-450 CYP2C19 inhibitors (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) …
Triclabendazole
Triclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans.[FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, Fasciola hepatica, which is also known as “the common liver fluke” or “the...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2A6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C19 inhibitors (strength unknown) …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Description: … In these patients, activated rFXIII has been shown to increase the mechanical strength of fibrin clots ... transglutaminase from subunit A cross-links fibrin and other proteins resulting in increased mechanical strength …
Diacerein
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea . Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2),...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2E1 Inhibitors (strength unknown) …
Phenelzine
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Matched Categories: … Cytochrome P-450 CYP2E1 Inducers (strength unknown) ... Cytochrome P-450 CYP2C19 inhibitors (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Levoketoconazole
Cushing's syndrome (CS) is underpinned by chronic hypercortisolism leading to multisystem morbidity, including effects on the cardiovascular and endocrine systems, metabolic syndrome with accompanying changes in body composition, neuropsychiatric effects, changes in blood pressure and chemistry, and opportunistic infections.[A244078, A244083] Ketoconazole has been used both on- and off-label to treat...
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inducers (strength unknown) ... Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Categories: … Cytochrome P-450 CYP2B6 Inducers (strength unknown) ... Cytochrome P-450 CYP2C19 Inducers (strength unknown) ... Cytochrome P-450 CYP2C8 Inducers (strength unknown) ... Cytochrome P-450 CYP2C9 Inducers (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP2C19 inhibitors (strength unknown) ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Hetacillin
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Description: … withdrawn from the market since it has been discovered that it has no therapeutic advantage compared to non-ester …
Hydrocortisone valerate
Approved
Vet approved
Matched Categories: … Cytochrome P-450 CYP2C8 Inducers (strength unknown) ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) …
Fexofenadine
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Displaying drugs 101 - 125 of 2696 in total