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Displaying drugs 126 - 150 of 14998 in total
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Technetium Tc-99m disofenin
Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Synonyms: … Technetium-99m-Diisopropyliminodiacetic Acid …
Matched Iupac: … 2-[({[2,6-bis(propan-2-yl)phenyl]carbamoyl}methyl)(carboxymethyl)amino]acetic acid (99Tc)technetium …
Matched Description: … Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with ... for liver uptake) as are other tracers from the iminodiacetic acid. ... the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary …
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins ... Hepatic and Reticulo Endothelial System …
Matched Iupac: … 2-[({[2,6-bis(propan-2-yl)phenyl]carbamoyl}methyl)(carboxymethyl)amino]acetic acid (99Tc)technetium …
Matched Description: … Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with ... for liver uptake) as are other tracers from the iminodiacetic acid. ... the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary …
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins ... Hepatic and Reticulo Endothelial System …
Bezafibrate
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Matched Description: … Antilipemic agent that lowers cholesterol and triglycerides. ... It decreases low density lipoproteins and increases high density lipoproteins. …
Matched Categories: … Fibric Acid Derivatives ... Benzamides and benzamide derivatives …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Matched Description: … Antilipemic agent that lowers cholesterol and triglycerides. ... It decreases low density lipoproteins and increases high density lipoproteins. …
Matched Categories: … Fibric Acid Derivatives ... Benzamides and benzamide derivatives …
Eprosartan
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid ... (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid ... (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Iupac: … ({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics …
Matched Iupac: … ({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics …
Phenoxymethylpenicillin
Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK. It is a phenoxymethyl analog of Penicillin G, or benzylpenicillin. An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by...
Approved
Vet approved
Matched Synonyms: … Phenoxymethylenepenicillinic acid ... 6-phenoxyacetamidopenicillanic acid ... 2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and ... heart disease or rheumatic or other acquired valvular heart disease when they undergo dental procedures and ... studies that were conducted, phenoxymethylpenicillin has been suggested by the American Heart Association and …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and ... heart disease or rheumatic or other acquired valvular heart disease when they undergo dental procedures and ... studies that were conducted, phenoxymethylpenicillin has been suggested by the American Heart Association and …
Mucor circinelloides f. circinelloides
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. ... Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. ... Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Synonyms: … 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones, joints ... [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of ... , thereby reducing serum uric acid levels. …
Matched Categories: … Preparations Inhibiting Uric Acid Production …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones, joints ... [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of ... , thereby reducing serum uric acid levels. …
Matched Categories: … Preparations Inhibiting Uric Acid Production …
Thiopental
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Synonyms: … Thiopentobarbituric acid ... 2-Thio-5-ethyl-5-sec-pentylbarbituric acid …
Matched Description: … It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. ... It does not produce any excitation but has poor analgesic and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. ... It does not produce any excitation but has poor analgesic and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives …
Technetium Tc-99m succimer
Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA), is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma...
Approved
Matched Synonyms: … Technetium Tc 99m dimercaptosuccinic acid …
Matched Iupac: … (2R,3S)-2,3-disulfanylbutanedioic acid (99Tc)technetium …
Matched Description: … Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid ... (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular ... L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved …
Matched Categories: … Indicators and Reagents …
Matched Iupac: … (2R,3S)-2,3-disulfanylbutanedioic acid (99Tc)technetium …
Matched Description: … Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid ... (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular ... L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved …
Matched Categories: … Indicators and Reagents …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated ... the EMA fully approved the drug on March 27, 2023. ... types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated ... the EMA fully approved the drug on March 27, 2023. ... types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Masoprocol
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Synonyms: … erythro-nordihydroguaiaretic acid ... Nordihydroguaiaretic acid ... meso-nordihydroguaiaretic acid …
Matched Description: … A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. ... It also serves as an antioxidant in fats and oils. [PubChem] ... The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. ... It also serves as an antioxidant in fats and oils. [PubChem] ... The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Hydrocortisone
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... hydrocortisone and mydriatics ... Hydrocortisone and derivatives ... hydrocortisone and antiseptics …
Matched Products: … Rodan and Fields Soothe ... Itch and Rash Cream ... Up and Up Anti Itch …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... hydrocortisone and mydriatics ... Hydrocortisone and derivatives ... hydrocortisone and antiseptics …
Matched Products: … Rodan and Fields Soothe ... Itch and Rash Cream ... Up and Up Anti Itch …
Sodium tartrate
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH...
Approved
Matched Synonyms: … Tartaric acid, disodium salt …
Matched Description: … Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless ... , and odorless crystals. ... It acts as an emulsifier and pH control agent in food products [L2590]. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless ... , and odorless crystals. ... It acts as an emulsifier and pH control agent in food products [L2590]. …
Matched Categories: … Alimentary Tract and Metabolism …
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents …
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acid ... (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … [DB00135] is a non-essential amino acid with a polar side group. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … [DB00135] is a non-essential amino acid with a polar side group. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pentobarbital
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(sec-pentyl)barbituric acid ... 5-ethyl-5-(1-methylbutyl)barbituric acid …
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Categories: … Hypnotics and Sedatives …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Synonyms: … α-phenyl-2-piperidineacetic acid methyl ester …
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and …
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and …
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Oxybuprocaine
Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Synonyms: … 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid ... 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Methysergide
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...
Approved
Matched Synonyms: … 1-Methyllysergic acid butanolamide ... 1-Methyl-D-lysergic acid butanolamide ... 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide …
Matched Description: … An ergot derivative that is a congener of lysergic acid diethylamide. ... Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Lysergic Acid ... Ergot Alkaloids and Derivatives …
Matched Description: … An ergot derivative that is a congener of lysergic acid diethylamide. ... Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Lysergic Acid ... Ergot Alkaloids and Derivatives …
Artesunate
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Synonyms: … Artesunic acid ... butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[ …
Matched Iupac: … 13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-yl]oxy}butanoic acid …
Matched Categories: … Artemisinin and derivatives ... artesunate and mefloquine ... artesunate and amodiaquine ... artesunate and pyronaridine ... artesunate, sulfalene and pyrimethamine …
Matched Iupac: … 13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-yl]oxy}butanoic acid …
Matched Categories: … Artemisinin and derivatives ... artesunate and mefloquine ... artesunate and amodiaquine ... artesunate and pyronaridine ... artesunate, sulfalene and pyrimethamine …
Cefoxitin
Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Products: … Cefoxitin and Dextrose …
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Products: … Cefoxitin and Dextrose …
Eflornithine
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... [A262823,L49318] Subsequently, on December 14, 2023, the FDA approved eflornithine again but under the ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and …
Matched Categories: … Skin and Mucous Membrane Agents ... Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... [A262823,L49318] Subsequently, on December 14, 2023, the FDA approved eflornithine again but under the ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and …
Matched Categories: … Skin and Mucous Membrane Agents ... Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Lomefloxacin
Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational
Matched Synonyms: … (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ... 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and …
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and …
Displaying drugs 126 - 150 of 14998 in total