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Displaying drugs 151 - 175 of 13781 in total

Varicella zoster vaccine (live/attenuated)

Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Description: … in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals ... Efficacy for prevention of shingles is highest in patients 60-69 years old and decreases with increasing ... efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients …
Matched Mixtures name: … Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung …
Matched Products: … VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze ... Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze …

Triamcinolone

Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Iupac: … (1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,2,10-trihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H …
Matched Description: … [L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection ... Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic ... rhinitis to acute exacerbations of multiple sclerosis. …
Matched Mixtures name: … Point Of Care Kit KM ... Hydroquinone 6% / Tretinoin 0.05% / Triamcinolone 0.025% ... Mlp A-2 …
Matched Categories: … Protein-Lysine 6-Oxidase, antagonists & inhibitors …
Matched Products: … Pro-C-Dure 6 Kit ... Hexatrione 2% ... KENALOG IN ORABASE …

Darunavir

Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6 ... -dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido …
Matched Iupac: … ]-1-phenylbutan-2-yl]carbamate ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido …
Matched Description: … inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of ... [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... [A2278,A2281] It was initially approved by the FDA in 2006. …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... combinations of sulfonamides …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … This leads to excretion of these amino acids and a decrease in ammonia levels. ... It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … S Panax All In One Mist …

Valoctocogene roxaparvovec

Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Description: … to produce factor VIII protein and increase the levels of active factor VIII in blood. ... Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that ... It is not approved for use in the United States. …
Matched Categories: … Cellular and Gene Therapy …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Synonyms: … 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid ... 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Salts cas: … 5987-82-6 …
Matched Products: … Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … It is used in a number of health and beauty products including hair care products such as shampoo, conditioner ... , leave-in conditioner, and de-tangling products. ... Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical …
Matched Mixtures name: … QYO QYO Tangerine Bright Moist All In One Cream ... The Bamboo Of Damyang Moisture Essence ... Childrens Mylicon All in One Tummy Relief for Kids …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Kendall 2-in-1 Cleanser ... The Bamboo Of Damyang Moisture ... The Bamboo Of Damyang Moisture Eye …

Clocortolone

Clocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Approved
Matched Iupac: … (1S,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-9b-chloro-5-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl …
Matched Description: … inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp. ... Clocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of …

Indigotindisulfonic acid

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Synonyms: … FD&C Blue #2 ... 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid …
Matched Description: … This compound is an acid-base indicator and is used in the production of food colorants and pH tests. ... Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. ... [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... of heart contractions. ... It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

Tyrothricin

Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Description: … This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely ... of the six predominant tyrocidines, TrcA/A1, TrcB/B1, TrcC/C1, and other more minor contributors) and ... microbial resistance during the over 60 years of therapeutic use the complex has provided [A36360]. …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Iupac: … gadolinium(3+) ion 4-carboxy-8,11-bis(carboxylatomethyl)-5-(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan …
Matched Description: … contrast agent (GBCA) used primarily for MR imaging of the liver. ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... [A1139] Gadobenate dimeglumine was approved by the FDA in November 2004 under the brand name MultiHance …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up ... 25% of the mixture. …
Matched Salts cas: … 32780-64-6 …
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride …

Abatacept

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … It is produced through recombinant DNA technology in mammalian CHO cells. ... 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. ... formulation of CTLA4-Ig into clinical trials (RG2077). …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …

Linoleic acid

Approved
Experimental
Matched Synonyms: … C18:2 9c, 12c omega6 todos cis-9,12-octadienoico …
Matched Categories: … Fatty Acids, Omega-6 …

Rotavirus vaccine

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … [Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection. ... Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq …
Matched Products: … ROTATEQ ORAL KULLANIM İÇİN 2 ML ÇÖZELTİ …

Oftasceine

Oftasceine is also referred to as Fluorexon. It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. It is a fluorescent dye or luminescent agent.
Approved
Matched Iupac: … 2-{[(7'-{[bis(carboxymethyl)amino]methyl}-3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]- ... 2'-yl)methyl](carboxymethyl)amino}acetic acid …
Matched Description: … It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. …

Ensulizole

Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... treatment provided protection against cyclobutane pyrimidine dimers and photosensitized the formation of …
Matched Mixtures name: … Olay Total Effects 7-IN-1 Anti-aging Uv Moisturizer Plus Touch Of Foundation ... Nioxin Scalp Treatment System 6 SPF 15 Sunscreen - Medium to Coarse Hair ... Hawaiian Tropic Herbal Tanning Mist 2 SPF …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. ... Morphine was granted FDA approval in 1941.[L12114] ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids …
Matched Salts cas: … 52-26-6 ... 596-15-6 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Oramorph 2 mg/ml Lösung zum Einnehmen ... Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern …

Pindolol

Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Synonyms: … 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol ... 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol ... 4-(2-hydroxy-3-isopropylaminopropoxy)-indole …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s. ... Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. ... focused on the treatment of arrhythmia. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans ... It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant ... Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis …
Matched Mixtures name: … Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Tracel Injektionslösung in einer Fertigspritze ... .-6 Concentrated …
Matched Products: … Selenase 100 Mikrogramm/2 ml - Lösung zum Einnehmen …

Bilastine

Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Approved
Investigational
Matched Iupac: … 2-[4-(2-{4-[1-(2-ethoxyethyl)-1H-1,3-benzodiazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoic …
Matched Description: … antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Olisir 6 mg/ml Augentropfen, Lösung …

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride ... NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE ... NITROPRUSIATO DE SODIO SOLUCION INYECTABLE POR 2 ML …

Octreotide

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. ... hormone, somatostatin, which inhibits the secretion of growth hormone. …
Matched Salts cas: … 135467-16-2 …
Matched Products: … Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,5 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,05 mg/ml Injektionslösung in einer Fertigspritze …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Iupac: … (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl ... ]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetamido)acetamido] ... )ethyl]carbamoyl}propyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl]carbamoyl ... {[(1S)-3-carboxy-1-{[(1S)-3-carboxy-1-{[(1S)-1-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl}-2-(4-hydroxyphenyl ... carbamoylpropanamido]acetamido}-3-carboxypropanamido]-3-phenylpropanamido]-4-carboxybutanamido]-4-{[(2S,3S)-1-[(2S)-2- …
Matched Description: … formation of thrombus. ... Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the ... Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …
Displaying drugs 151 - 175 of 13781 in total