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Displaying drugs 151 - 175 of 14605 in total

Dichloroacetic acid

Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity...
Approved
Investigational
Matched Description: … and removal of a wide variety of skin and tissue lesions), but was cancelled post market. ... DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization …

L-Lactic acid

Approved
Experimental

Tolazoline

A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …

Alprazolam

Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Description: … ketoconazole and itraconazole. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Potassium bicarbonate

Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Description: … Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. ... [T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for …
Matched Mixtures name: … Coenzyme Q10 Isotonix Vitamin and Mineral Supplement ... Isotonix Advanced B-complex Vitamins With Potassium and Magnesium …
Matched Categories: … Alimentary Tract and Metabolism …

Oxycodone

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Mixtures name: … Oxycodone and Aspirin ... Oxycodone and Aspirin ... Oxycodone and Acetaminophen …
Matched Categories: … oxycodone and naloxone ... oxycodone and ibuprofen ... oxycodone and naltrexone ... oxycodone and paracetamol ... oxycodone and acetylsalicylic acid …

Interferon alfa-n3

Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Description: … including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). ... Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …

Epicriptine

Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. To know more about the mixture please visit DB01049
Approved
Matched Description: … Epicriptine differs from the alpha form on the position of one methyl group. ... Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro ... Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture …

Oxymetholone

Oxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth in malnourished or underdeveloped patients. Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes....
Approved
Illicit
Matched Description: … brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and ... Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and …
Matched Categories: … moxonidine and diuretics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …

Droxidopa

Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a...
Approved
Investigational
Matched Description: … associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is the ... It is approved for use in Japan and is currently in trials in the U.S. ... The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated …
Matched Categories: … Adrenergic alpha-Agonists ... Epinephrine and similars ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic and Dopaminergic Agents ... Adrenergic alpha-2 Receptor Agonists …

Indigotindisulfonic acid

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Description: … This compound is an acid-base indicator and is used in the production of food colorants and pH tests. ... Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and …
Matched Categories: … Tests for Renal Function and Ureteral Injuries …

Propylhexedrine

Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.
Approved
Matched Description: … Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. …
Matched Categories: … Adrenergic alpha-Agonists …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and ... It is found naturally in citrus fruits and many vegetables. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Cavan Alpha ... Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge ... Hvp Chelated Cal/mag With Zinc and Vitamins C and D …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... Genito Urinary System and Sex Hormones …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …

Quinine

An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in...
Approved
Matched Description: … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis ... Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that ... , because of its direct effects on muscle membrane and sodium channels. …
Matched Categories: … Quinine and stereoisomer ... Antiparasitic Products, Insecticides and Repellents …

Beta carotene

Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Description: … It is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits. ... [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. …
Matched Mixtures name: … Cavan Alpha ... Beta C and E Tab ... Eden With Vitamins A, C, and E …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Emollients and Protectives …

Dutasteride

Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary ... 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists ... tamsulosin and dutasteride ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Caffeine

Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … [A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns ... Caffeine is similar in chemical structure to [Theophylline] and [Theobromine]. ... variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and …
Matched Mixtures name: … dihydrocodeine bitartrate and aspirin and caffeine DC ... Asa and Caffeine ... Ac and C Tab 1/8gr …
Matched Categories: … caffeine and sodium benzoate ... Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Anorexigenic Agents & Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Caffeine and Sodium Benzoate …

Ammonium lactate

Ammonium lactate is the ammonium salt of lactic acid.
Approved
Matched Categories: … alpha-Hydroxy Acid …

Etilefrine

Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched Description: … Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic and Dopaminergic Agents …

Certolizumab pegol

Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha ... [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated ... is significantly more affordable when compared to other existing TNF-alpha therapies as it can be done …
Matched Categories: … Tumor necrosis factor alpha (TNF-alpha) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Desipramine

Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... as amitriptyline and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Displaying drugs 151 - 175 of 14605 in total