Displaying drugs 1751 - 1775 of 8471 in total
Alcaftadine
Alcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4,7-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3,5,10,12-pentaene-6- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lotilaner
Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … )-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)- ... )-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide ... 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl …
Matched Iupac: … 2-({3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen ... -2-yl}formamido)-N-(2,2,2-trifluoroethyl)acetamide …
Matched Iupac: … 2-({3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen ... -2-yl}formamido)-N-(2,2,2-trifluoroethyl)acetamide …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Calcium carbonate
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Mixtures name: … Super Daily No 2 ... Antacid 2 Tablets ... ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET …
Matched Products: … EFERCAL 1000 MG EFERVESAN TABLET, 60 ADET …
Matched Products: … EFERCAL 1000 MG EFERVESAN TABLET, 60 ADET …
Oxyphenbutazone
Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.
Approved
Withdrawn
Matched Iupac: … 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Categories: … Non COX-2 selective NSAIDS …
Phleum pratense pollen
Phleum pratense pollen allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Mixtures name: … 8 Southern Grass Mix ... 8 Southern Grass Mix ... Pollens - Grasses, Grass Mix 8 …
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Synonyms: … 2-Hydroxy-3,5-dichlorophenyl sulfide ... 2-Hydroxy-3,5-dichlorophenyl sulphide ... Bis(3,5-dichloro-2-hydroxyphenyl) sulfide …
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Xenon Xe-129
Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI). Lung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces.[A255178,A255183] The use of hyperpolarized...
Approved
Matched Description: … [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile …
Dihydrostreptomycin
Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl …
Matched Iupac: … )-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl ... N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl …
Matched Iupac: … )-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl ... N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl …
Edotreotide gallium Ga-68
Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. Dotatate gallium Ga-68 is used for a similar indication. Dotatate gallium Ga-68 has lower tumor uptake but this...
Approved
Matched Iupac: … (68Ga)gallium(3+) 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan ... -2-yl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18 ... -pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl …
Matched Description: … Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane …
Matched Description: … Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane …
Oxymorphone
An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … On June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid …
Matched Salts cas: … 357-07-3 …
Matched Description: … On June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid …
Matched Salts cas: … 357-07-3 …
Thioridazine
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine ... 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Salts cas: … 130-61-0 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Novo-ridazine (thioridazine Oral Suspension) - 2 mg/ml …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Salts cas: … 130-61-0 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Novo-ridazine (thioridazine Oral Suspension) - 2 mg/ml …
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... L-β-3-indolylalanine ... (S)-α-amino-1H-indole-3-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …
Clove oil
Clove oil is obtained by extraction from the dried flower buds of the clove plant. Traditionally, it has been used as a flavouring spice in foods, or as a fragrance. It is also found in topical analgesics. Clove oil has shown to exert some antimicrobial activities. The antioxidant and antimicrobial...
Approved
Nutraceutical
Matched Mixtures name: … DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl …
Matched Iupac: … (3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2 …
Matched Iupac: … (3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2 …
Tedizolid phosphate
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Dimercaprol
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched Synonyms: … 1,2-dimercapto-3-propanol ... 3-hydroxy-1,2-propanedithiol …
Influenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Influenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Nitrazepam
A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Matched Synonyms: … 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one ... 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one ... 7-nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lacosamide
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Synonyms: … (R)-2-acetamido-N-benzyl-3- methoxypropionamide ... (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDE ... (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide …
Matched Iupac: … (2R)-N-benzyl-2-acetamido-3-methoxypropanamide …
Matched Iupac: … (2R)-N-benzyl-2-acetamido-3-methoxypropanamide …
Lindane
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Droperidol
A butyrophenone with general properties similar to those of haloperidol. It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a...
Approved
Vet approved
Matched Synonyms: … 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone ... 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone ... 1-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one …
Matched Iupac: … 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dinoprostone
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Products: … PROSTIN E 2 ... PROSTIN E2 VAGINAL TABLET 3 mg ... Prostin E2 3 mg - Vaginaltabletten …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Products: … PROSTIN E 2 ... PROSTIN E2 VAGINAL TABLET 3 mg ... Prostin E2 3 mg - Vaginaltabletten …
Displaying drugs 1751 - 1775 of 8471 in total