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Displaying drugs 1876 - 1900 of 15428 in total
Approved
Nutraceutical
Matched Mixtures name: … PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins ... Complete Multivitamins and Minerals for Children …
Matched Categories: … Vitamin C and analogues ... Diet, Food, and Nutrition …
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Iupac: … 1-({4-[2-(azepan-1-yl)ethoxy]phenyl}methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol …
Matched Description: … It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. ... In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the …
Matched Salts name: … Bazedoxifene acetate
Matched Categories: … Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Iupac: … -tribenzyl-31-(carbamoylmethyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-[(1H-indol-3-yl)methyl
Matched Description: … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating ... Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 …
Matched Salts name: … Somatostatin acetate
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Hormone receptor (HR) positive, especially estrogen receptor-positive, HER2-negative breast cancer is the most common subtype of metastatic breast cancer, resulting in more than 400,000 deaths annually. Although endocrine-based therapy is the first line of treatment, resistance eventually emerges, leaving chemotherapy the only but often ineffective treatment left. Therefore, significant research...
Approved
Investigational
Matched Description: … based on favorable results obtained from the CAPItello-291 trial, where the combination of capivasertib and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Approved
Withdrawn
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Description: … It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. ... Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones …
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and dapagliflozin ... saxagliptin and dapagliflozin ... sitagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Approved
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... and acute uncomplicated gonococcal urethritis etc. ... Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. …
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... inhibits lipolysis and proteolysis among many other functions. ... The myristoyl side chain increases self-association and albumin binding. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is...
Approved
Withdrawn
Matched Iupac: … (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine …
Matched Description: … It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought ... Safety Communication requesting the manufacturer of Belviq (lorcaserin hydrochloride tablets, 10 mg) and ... hydrochloride extended-release tablets, 20 mg) to voluntarily withdraw these products from the U.S. market, and
Matched Categories: … Alimentary Tract and Metabolism …
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Pivalate ester analog of ampicillin.
Approved
Matched Iupac: … [(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbonyloxy]methyl
Erdosteine is a drug that causes a breakdown of mucus, also known as a mucolytic agent. It is a thiol derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis. This drug contains sulfhydryl groups which are released after erdosteine undergoes hepatic...
Approved
Investigational
Matched Iupac: … 2-({[(2-oxothiolan-3-yl)carbamoyl]methyl}sulfanyl)acetic acid …
Matched Description: … and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol ... Erdosteine 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly ... Erdosteine has been shown to be safe and well tolerated in clinical trials. …
Matched Categories: … Cough and Cold Preparations …
Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched Description: … It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and ... [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects ... [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Cholagogues and Choleretics …
Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure.
Approved
Matched Description: … ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Vet approved
Approved
Matched Mixtures name: … Ionosol and Dextrose …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine...
Approved
Matched Iupac: … (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6(17),7,9,15 …
Matched Description: … and extended-release tablets and solution. ... [A201968] Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and ... until the early 1990s due to difficulties in extraction and synthesis. …
Cavia porcellus skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Guinea Pig Hair and Epithelia …
Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.
Approved
Matched Description: … Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and
Matched Mixtures name: … Maxine Vitamin and Mineral Supplement …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Approved
Experimental
Matched Mixtures name: … Polyethylene Glycol 3350 and electrolytes - Unflavored …
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Categories: … Hypnotics and Sedatives …
Displaying drugs 1876 - 1900 of 15428 in total