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Displaying drugs 176 - 200 of 12842 in total
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Humanized pd-1 blocking antibody hx-008 ... musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008 .kappa ... Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus …
Matched Description: … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. …
Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Synonyms: … trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride …
Matched Iupac: … 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl]urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Dextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Approved
Illicit
Matched Synonyms: … (S)-1-phenyl-2-propylamine ... (S)-1-phenyl-2-aminopropane ... (+)-(S)-amphetamine …
Matched Iupac: … (2S)-1-phenylpropan-2-amine …
Matched Salts cas: … 64770-52-1
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Synonyms: … 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … GEMTERO 1 G ... GEMTAZ 1 GM ... FOTINEX 1 G …
Approved
Investigational
Matched Synonyms: … Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-21-(1-oxopropoxy …
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Synonyms: … 1-N-Allyl-14-hydroxynordihydromorphinone …
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{ …
Matched Salts cas: … 357-08-4
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... TILIDIN 50/4 RETARD 1A PHA ... TILIDIN 50/4 RETARD 1A PHA …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol …
Matched Mixtures name: … PNV Tabs 29-1 ... Trinatal Rx 1 ... PNV Tabs 29-1
Matched Products: … Riboflavin-S Tab 25mg …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. ... -TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE …
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... -3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0 …
Matched Products: … JEVTANA 60MG/1,5ML INFÜZYONLUK KONSANTRE ÇÖZELTI VE ÇÖZÜCÜ, 1 ADET VE 1 ÇÖZÜCÜ ... CABATAX 60 MG/1,5 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... NEUTAXAN 60 MG/ 1.5 ML İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Synonyms: … 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline ... 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinoline ... 7-chloro-4-[4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino]quinoline …
Matched Iupac: … 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol …
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. …
Matched Salts cas: … 747-36-4
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries...
Approved
Matched Synonyms: … ANTINEOPLASTON AS 2-1 COMPONENT PHENYLACETIC ACID ... ANTINEOPLASTON AS2-1 COMPONENT PHENYLACETIC ACID …
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2- ... syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Salts cas: … 68401-82-1
Matched Products: … CEFIZOX 1 GR FLAKON, 1 ADET ... CEFİZOX 1 G IM ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET ... CEFİZOX 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET …
An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Synonyms: … D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol …
Matched Iupac: … 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide …
Matched Mixtures name: … CORTIFENOL H POMADA OFTALMICA 4 G …
Matched Products: … VENAFEN-S EYE DROP ... Chloroptic Oph Ont 1% ... CHLOROP EYE OINTMENT 1 % …
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one ... dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1- …
Matched Iupac: … -1-yl 2,2-dimethylbutanoate ... (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1
Matched Mixtures name: … TIAZOMET S® ... TIAZOMET S® ... ZETIROL S®10/20 MG TABLETAS …
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … 2-methoxyl-4-vinylphenol ... 1-hydroxy-2-methoxybenzene …
Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Synonyms: … (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0 ... (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(N-hydroxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo …
Matched Products: … MENACEF 250MG/5ML ORAL SÜSPANSIYON HAZIRLAMAK İÇİN KURU TOZ, (100 mL) 1 ŞIŞE ... MENACEF 125 MG/5 ML ORAL SÜSPANSIYON HAZIRLAMAK İÇİN KURU TOZ, (100 mL) 1 ŞIŞE …
Approved
Matched Synonyms: … Acetic acid, magnesium salt (2:1) …
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is...
Approved
Investigational
Vet approved
Matched Synonyms: … Calcium 2-hydroxypropanoate (1:2) …
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Synonyms: … 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine …
Matched Iupac: … 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Synonyms: … 2,3-Dimethyl-1-phenyl-5-pyrazolone …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil …
Matched Iupac: … 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... (S)-Nicotine ... (S)-(−)-nicotine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Habitrol Step 1 ... NICOTINE Transdermal System Step 1 ... Nicotine Transdermal System Step 1
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Synonyms: … acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1- …
Matched Iupac: … (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy …
Matched Products: … ENJEKSİYON İÇİN LİYOFILIZE TOZ, 1 ADET …
Displaying drugs 176 - 200 of 12842 in total