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Displaying drugs 176 - 200 of 9118 in total
Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Products: … B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 5 ADET ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 5 FLAKON …
Benzhydrocodone is a benzylic prodrug of hydrocodone. It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse. Benzhydrocodone is indicated for use in the short-term management of pain. It was first approved by the FDA in February 2018 in combination with...
Approved
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Synonyms: … (1R-(1-α,2-β,5-α))-5-methyl-2-(1-methylethyl)cyclohexanol ... (1alpha,2beta,5alpha)-5-methyl-2(1-methylethyl)cyclohexanol …
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol …
Matched Mixtures name: … s Cream ... LUKE`S OIL ... ATLETIC´S
Matched Products: … Mag 5 Pt Warming Formula ... Myoflex Ice Cold Gel 5% ... Ion-TO Scalp Cleanser S
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Mixtures name: … Multitrace-5 ... .-6 Concentrated ... Multitrace-5
Matched Products: … FORTZINK JARABE 20 MG/5 ML ... CHINKO 15 MG/5 ML SURUP, 100 ML ... ZİNCO 25 MG/5 ML ŞURUP, 100 ML …
Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of spirochetes, Toxoplasma gondii and Cryptosporidium. Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in...
Approved
Matched Iupac: … 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan ... -2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-10-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan ... -2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde …
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils and basophils. It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R,...
Approved
Investigational
Matched Description: … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta ... antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5
Matched Categories: … Interleukin-5 Receptor alpha-directed Cytolytic Antibody ... Interleukin 5 Receptor alpha-directed Antibody Interactions …
An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Products: … VENAFEN-S EYE DROP ... GEMYSETIN 0.25 G OVUL, 6 OVUL ... ENCLOR EAR DROPS 5% W/V …
Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing chemotherapy for extensive stage small cell lung cancer. CDK4 and CDK6 inhibitors have been investigated since the mid 1990s for their use in tumorigenesis...
Approved
Investigational
Matched Iupac: … [7.4.0.0^{2,7}]tridecane]-1'(9'),7',10',12'-tetraen-6'-one ... 12'-{[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}-2',5',11',13'-tetraazaspiro[cyclohexane-1,3'-tricyclo …
Matched Categories: … Cyclin-dependent Kinase 6 Inhibitors …
Lolium perenne pollen is the pollen of the Lolium perenne plant. Lolium perenne pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 6 Grass Mix ... 6 Grass Mix ... Mix Of 6 Standardized Grass Pollen …
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Description: … It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. …
Matched Mixtures name: … CLE DE PEAU BEAUTE PW FOUNDATION s I10 ... CLE DE PEAU BEAUTE PW FOUNDATION s O10 ... CLE DE PEAU BEAUTE PW FOUNDATION s O20 …
Matched Products: … 6 Creme 410 ... 6 Lait Solaire ... Revitalizing Concealer - Stk 5% …
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
Approved
Investigational
Matched Iupac: … (1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-5-(hydroxyimino)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en …
Matched Mixtures name: … Evra -(6/0.75) ... EVRA TRANSDERMAL PATCH (6 mg/600 mcg) …
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Synonyms: … 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)- ... 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide ... 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide …
Matched Iupac: … 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide …
Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 6 Grass Mix ... 6 Grass Mix ... Mix Of 6 Standardized Grass Pollen …
A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells. An oral formulation of L-glutamine was approved...
Approved
Investigational
Nutraceutical
Matched Synonyms: … (S)-2,5-diamino-5-oxopentanoic acid ... Glutamic acid 5-amide ... L-Glutaminsäure-5-amid …
Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the...
Approved
Investigational
Matched Products: … FASLODEX® 250 MG / 5 ML ... FASLODEX SOLUTION FOR INJECTION 250MG/5 ML ... ERANFU® SOLUCION INYECTABLE 250 MG/5 ML. …
Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Approved
Matched Products: … EMADİNE %0.05 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Products: … APFECTO %0.3 OFTALMİK SÜSPANSİYON, 5 ML ... APFECTO %0.1 GÖZ DAMLASI, SÜSPANSİYON, 5 ML ... NEVANAC %0,1 STERIL SUSPANSIYON GOZ DAMLASI, 5 ML …
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Salts cas: … 41733-55-5
Matched Mixtures name: … Lasitace 5 mg/40 mg Kapseln ... Lasitace 5 mg/20 mg Kapseln …
Matched Products: … FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET ... FUROSON 20 MG/2 ML IM/IV AMPUL, 5 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 ADET …
Agrostis gigantea pollen is the pollen of the Agrostis gigantea plant. Agrostis gigantea pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … GRASS MIX Number 4-S ... GRASS MIX Number 4-S ... 6 Grass Mix …
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Iupac: … 6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl]formamido}-5- …
Matched Products: … DESMOVITAL %0,1 MG/ML BURUN SPREYI, 6 ML …
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Synonyms: … 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide ... 5-acetamido-1,3,4-thiadiazole-2-sulfonamide ... 5-acetylamino-1,3,4-thiadiazole-2-sulfonamide …
Matched Iupac: … N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide …
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Approved
Matched Iupac: … 5-{N-[3-(N-{3,5-bis[(2,3-dihydroxypropyl)carbamoyl]-2,4,6-triiodophenyl}acetamido)-2-hydroxypropyl]acetamido …
Displaying drugs 176 - 200 of 9118 in total