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Displaying drugs 201 - 225 of 1338 in total

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved

Perindopril

Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers …

Thrombin

Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Description: … reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium …

Nebivolol

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Categories: … Beta blocking agents and calcium channel blockers …

Capsicum oleoresin

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved

Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Salts name: … Telmisartan sodium …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers …

Olopatadine

Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational

Phenyltoloxamine

Phenyltoloxamine is an antihistamine drug with sedative and analgesic effects. It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. It is available in combination products that also contain other analgesics and antitussives such as acetaminophen. Phenyltoloxamine citrate is the more common salt form...
Approved

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Mixtures name: … Calcium Magnesium With Potassium Tab ... Aminosyn II with Electrolytes in Dextrose with Calcium ... Aminosyn II with Electrolytes in Dextrose with Calcium …

Methacholine

Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in which the smooth muscle in the airways (ASM) excessively contracts in response to stimuli, reducing pulmonary function and causing symptoms such as difficulty breathing.[A229598, A229603] Although the underlying pathology of AHR is complex, ASM contraction can...
Approved
Investigational

Viltolarsen

Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational

Latanoprostene bunod

Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure. As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle...
Approved
Investigational

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Mixtures name: … Top Care Flu and Sore Throat ... Top Value Effervescent Cold Relief ... Top Care Day Time Multi Symptom Relief …

Sodium glycerophosphate

Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Approved
Matched Synonyms: … Disodium glycerol phosphate ... Sodium glycerophosphate anhydrous …
Matched Name: … Sodium glycerophosphate …
Matched Description: … Sodium glycerophosphate is one of several glycerophosphate salts. ... It is used clinically to treat or prevent low phosphate levels [FDA Label]. ... Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. …
Matched Salts name: … Sodium glycerophosphate hydrate …
Matched Categories: … Phosphate salts ... sodium glycerophosphate …

Calcium Phosphate

Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Approved
Matched Synonyms: … Calcium phosphates ... Phosphoric acid, calcium salt …
Matched Name: … Calcium Phosphate …
Matched Description: … Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient …
Matched Mixtures name: … Calcium PNV ... Milk Calcium With Vitamins C, D, and Phosphorous ... Milk Calcium With Vitamins C, D, and Phosphorous …
Matched Salts name: … Calcium phosphate, tribasic ... Calcium phosphate, dibasic …
Matched Categories: … calcium phosphate ... Phosphate salts ... Calcium Salts ... Calcium Compounds ... ascorbic acid (vit C) and calcium …

Prednisolone phosphate

Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Synonyms: … Prednisolone 21-phosphate ... Prednisolone 21-(dihydrogen phosphate) …
Matched Name: … Prednisolone phosphate …
Matched Description: … [A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144] ... Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Salts name: … Prednisolone sodium phosphate …
Matched Products: … Prednisolone Sodium Phosphate ... Prednisolone Sodium Phosphate ODT ... Minims Prednisolone Sodium Phosphate …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium acid carbonate ... Sodium hydrogen carbonate ... Sodium bicarbonate …
Matched Name: … Sodium bicarbonate …
Matched Iupac: … sodium hydrogen carbonate …
Matched Description: … Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte …
Matched Mixtures name: … Top Value Effervescent Pain Relief ... Top Value Effervescent Pain Relief ... Phoxilium 1.2 mmol/l phosphate solution for haemodialysis/haemofiltration …
Matched Categories: … Sodium Compounds ... sodium bicarbonate ... sodium bicarbonate …
Matched Products: … Sodium Bicarbonate ... Sodium Bicarbonate 5 gr ... SODIUM BICARBONATE …

Dipotassium phosphate

Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Synonyms: … Dibasic potassium phosphate ... Dipotassium acid phosphate ... Di-potassium hydrogen phosphate …
Matched Name: … Dipotassium phosphate …
Matched Iupac: … dipotassium hydrogen phosphate …
Matched Description: … Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Mixtures name: … Potassium Phosphate Inj 3mmp/ml ... Aminosyn II with Electrolytes in Dextrose with Calcium ... Aminosyn II with Electrolytes in Dextrose with Calcium …
Matched Categories: … Phosphate salts …

Silicon

Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).
Approved
Investigational
Matched Name: … Silicon …
Matched Iupac: … silicon …
Matched Description: … Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine …
Matched Mixtures name: … Calcium Magnesium Sulfur Silicon - Tab ... Active Calcium Plus Magnesium, Vitamin D and Silicon ... Actical Plus Calcium-magnesium-vitamin D3-silicon Chewable …

Stem bromelain

The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn wound eschar debridement agent that has been approved by the EMA since 2012 and marketed under the brand name Nexobrid [FDA Label]. Bromelain itself belongs to a category of protein-digesting enzymes that are...
Approved
Investigational
Matched Synonyms: … Bromelain, stem ... Pineapple stem bromelain …
Matched Name: … Stem bromelain …
Matched Description: … , the general term bromelain typically refers to stem bromelain [A27198]. ... The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn ... belongs to a category of protein-digesting enzymes that are obtained commercially from the fruit or stem …

Sodium phosphate, monobasic, unspecified form

Approved
Matched Name: … Sodium phosphate, monobasic, unspecified form …
Matched Mixtures name: … Phosphate ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose …
Displaying drugs 201 - 225 of 1338 in total