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Displaying drugs 201 - 225 of 14566 in total

Pivampicillin

Pivalate ester analog of ampicillin.
Approved
Matched Categories: … Penicillins With Extended Spectrum …

Levamisole

Levamisole is an antihelminthic drug that was commonly used for the treatment of parasitic, viral, and bacterial infections. It was manufactured by Janssen and first used in 1969 as an agent to treat worm infestations Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer....
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … with rheumatoid arthritis. ... [A178117] This drug has also been used in combination with other drugs for the treatment of various cancers ... immunomodulatory effects, this drug has been studied in the treatment of various immune-mediated diseases, with …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …

DL-dimyristoylphosphatidylcholine

A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Approved
Matched Description: … A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. …
Matched Categories: … Indicators and Reagents …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis ... Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

Mycophenolic acid

Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Description: … and antiviral properties. ... to optimize efficacy and minimize toxicity. ... [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A6 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index …

Diethylcarbamazine

An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Approved
Investigational
Vet approved
Matched Description: … anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with …
Matched Categories: … Piperazine and Derivatives ... Antiparasitic Products, Insecticides and Repellents …

Rimantadine

An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …

Naftifine

Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Approved
Matched Description: … Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical ... , Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. ... treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum …

Pentetic acid

Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Description: … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … type 2 diabetes in conjunction with diet and exercise. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control ... hospitalization for heart failure in adults with chronic kidney disease in April 2021. …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and dapagliflozin ... saxagliptin and dapagliflozin ... sitagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …

Piperonyl butoxide

Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as...
Approved
Vet approved
Matched Description: … It is used for the treatment of head, pubic (crab), and body lice. ... its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and …
Matched Mixtures name: … R & C Shampoo With Conditioner ... Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer …

Efavirenz

Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Description: … For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with ... Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …

Uridine triacetate

Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Description: … It reduces toxicity and cell-death associated with two cytotoxic intermediates: 5-fluoro-2'-deoxyuridine ... When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …

Ampicillin

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Description: … Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum …
Matched Mixtures name: … Ampicillin and Sulbactam ... Ampicillin and Sulbactam ... Ampicillin and Sulbactam …
Matched Categories: … Penicillins With Extended Spectrum …

Cefepime

Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Description: … , especially those with renal impairment, may develop neurotoxicity. ... [A249050] In general, cefepime seems to be well tolerated; however, patients treated with this antibiotic ... Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose …

Betamethasone

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics ... betamethasone and antibiotics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% …

Pirfenidone

Pirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate...
Approved
Investigational
Matched Description: … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that ... Pirfenidone is a synthetic pyridone drug. ... fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Eravacycline

Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Description: … of the tetracycline class with activity against clinically significant gram-negative, gram-positive ... Eravacycline, known as _Xerava_ by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic ... aerobic, and facultative bacteria. …

Atosiban

Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor. Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form. Atobisan was developed by the Swedish...
Approved
Investigational
Matched Description: … Atosiban is an inhibitor of the hormones oxytocin and vasopressin. ... Although initial studies suggested it could be used as a nasal spray and hence would not require hospital ... Atosiban is licensed in proprietary and generic forms for the delay of imminent pre-term birth in pregnant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Description: … Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. ... Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …

Quinestrol

The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Telavancin

Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Approved
Matched Description: … Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant ... skin and subcutaneous tissue infections among others. ... Staphylococcus aureus (MRSA) and other gram-positive bacteria. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Diethylstilbestrol

A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Description: … A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. ... (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products …
Matched Categories: … Synthetic Estrogens, Plain ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... its enzymatic activity, thereby interfering with DNA synthesis. ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Displaying drugs 201 - 225 of 14566 in total