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Displaying drugs 2351 - 2375 of 9608 in total
Paricalcitol
Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Approved
Investigational
Matched Description: … Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated …
Deoxycholic acid
Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve...
Approved
Floxuridine
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Description: … malignant neoplasms of the liver and gastrointestinal tract. ... It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in …
Autologous cultured chondrocytes
Autologous cultured chrondrocytes are used as autologous cell therapy to repair articular cartilage injuries in the knee (femoral condyle) due to acute or repetitive trauma. It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods. The surgical implantation shows a tolerable safety profile and...
Approved
Investigational
Adenine
A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Description: … A purine base and a fundamental unit of adenine nucleotides. …
Vasopressin
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Description: … [A228013] Despite a wide variety of functions, exogenous vasopressin is primarily used to control blood ... [A228008, A228013, A228018, L31413]
The vasopressive effect of posterior pituitary gland extracts …
Isoxsuprine
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … It is used in the treatment of peripheral vascular disease and in premature labor. ... A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. …
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Description: … I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of …
Talc
Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes.
Although talc has been widely used...
Approved
Matched Description: … Talc is a mineral composed primarily of magnesium, silicon and oxygen. ... In fact, recent studies have reported that talc increases the risk of ovarian and endometrial cancers …
Edetate disodium anhydrous
Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Approved
Vet approved
Docosanol
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes...
Approved
Investigational
Matched Description: … Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of …
Flumethasone
Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Approved
Vet approved
Matched Description: … As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. …
Tetracosactide
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Description: … that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of ... -24), a segment similar in all species, contains the biological activity that stimulates production of ... The complex results in a product whose absorption in man is effected over a longer period of time as …
Levobunolol
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Description: … A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma. …
Darvadstrocel
Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted from the subdermal adipose tissue of healthy donors via liposuction. Darvadstrocel was first approved by the European Commission on March 23, 2018, under the brand name Alofisel. It is indicated for the treatment of complex perianal fistulas...
Approved
Experimental
Matched Description: … from the subdermal adipose tissue of healthy donors via liposuction. ... Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted ... Perianal fistula is a common manifestation of Crohn’s disease and is often difficult to manage, as it …
Tetrachlorodecaoxide
WF10 is a chlorite-based, immunomodulating drug is developed by Nuvo Research Inc. Certain preclinical evidence and clinical pilot data suggest that WF10 may be effective in treating certain cancers. The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white blood cell) by modulating the...
Approved
Investigational
Matched Description: … in combination with Xeloda (capecitabine) in the treatment of pancreatic cancer. ... The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white ... The Corporation has commenced a Phase II clinical trial in an effort to demonstrate the efficacy of WF10 …
Selenomethionine
Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can be produced from post-structural modifications. In vivo, selenomethionine plays an essential role in acting as an antioxidant, where it depletes...
Approved
Investigational
Matched Description: … In comparison to selenite, which is the inorganic form of selenium, the organic form of selenomethionine ... antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of ... laboratories where its incorporation into proteins that need to be visualized enhances the performance of …
Light green SF yellowish
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Description: … the dye and increased tendency of the dye to fade. ... The maximum absorption of light green SF yellowish is at 630 (422) nm. ... Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining …
Estradiol dienanthate
Estradiol Dienanthate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … Ester pro-drugs of estradiol are therefore considered to be bioidentical forms of estrogen [T84]. ... Estradiol Dienanthate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex …
Metocurine iodide
Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent. It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine release and has some ganglion blocking activity. Metocurine...
Approved
Withdrawn
Matched Description: … It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of ... muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine ... advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of …
Trimethadione
An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
Approved
Matched Description: … An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of …
Paramethadione
Paramethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.
Approved
Carbamide peroxide
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … the effectiveness of this ingredient as an oral wound healing agent [L1976]. ... also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products …
Vibrio cholerae CVD 103-HgR strain live antigen
Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Description: … Two serogroups of _V. cholerae_, O1 and O139, are causative agents of epidemic cholera. ... Serogroup O1 is responsible for the majority of cholera outbreaks. ... _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization …
Displaying drugs 2351 - 2375 of 9608 in total