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Displaying drugs 1 - 25 of 1334 in total
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … Cysteamine
Matched Name: … Cysteamine
Matched Description: … [A218721] Several preparations of cysteamine exist for the treatment of cystinosis manifestations, ... [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis …
Matched Salts name: … Cysteamine bitartrate ... Cysteamine hydrochloride …
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … para-aminohippurate ... para-aminohippuric acid ... N-(para-aminobenzoyl)glycine …
Matched Categories: … para-Aminobenzoates …
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine ... 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene …
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … para-Aminobenzoic acid …
Matched Categories: … para-Aminobenzoates …
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … para-aminobenzenesulfonamide …
Brazil nut allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Castanha do para whole …
Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S,...
Approved
Matched Synonyms: … 2-para-Anisyl-1,3-indandione …
Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties. When mixed with a plasticizer, this chemical forms a plastic explosive. It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina . It is a pentaerythritol nitrate in...
Approved
Matched Synonyms: … PENT
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Products: … DIFOLTA 20 MG/ML SOLUCION PARA INFUSION …
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-1-methyl-5-(1-methyl-pent-2-ynyl)-pyrimidine-2,4,6-trione …
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of cisplatin with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Approved
Matched Products: … CARBOHET® 10 MG/ML SOLUCIÓN CONCENTRADA PARA INFUSIÓN ... CARBOPLATINO 150 MG/15 ML SOLUCION CONCENTRADA PARA INFUSION …
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Products: … DIALPEN POLVO PARA SUSPENSION 5.0% ... DICLOXACILINA POLVO PARA SUSPENSIÓN ... DIALPEN® POLVO PARA SUSPENSION 5.0% …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Products: … NOVOEIGHT® 2000 UI POLVO Y SOLVENTE PARA SOLUCIÓN PARA INYECCIÓN ... NOVOEIGHT® 3000 UI POLVO Y SOLVENTE PARA SOLUCIÓN PARA INYECCIÓN ... NOVOEIGHT®500UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE …
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Products: … BENLYSTA 120 MG POLVO LIOFILIZADO CONCENTRADO PARA SOLUCION PARA INFUSION ... BENLYSTA 400 MG POLVO LIOFILIZADO CONCENTRADO PARA SOLUCION PARA INFUSION …
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Products: … GRANULOS PARA SUSPENSION ORAL ... CEFALEXINA POLVO PARA SUSPENSION ... CEFALEXINA POLVO PARA SUSPENSION 5% …
The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Products: … KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION. …
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Products: … BORTEZOMIB PARA INYECCIÓN 3.5 MG ... BORTOMA (BORTEZOMIB) 3.5 MG POLVO ESTERIL PARA INYECCION ... TEBIDE® 350 µG POLVO LIOFILIZADO ESTÉRIL PARA RECONSTITUIR …
Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Products: … CURLEM 4 MG LIOFILIZADO PARA SOLUCION INYECTABLE ... VECURONIO BROMURO 10 MG /2.5 ML POLVO LIOFILIZADO PARA SOLUCION INYECTABLE ... BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Products: … OCREVUS® CONCENTRADO PARA SOLUCION PARA INFUSION 300MG/10ML …
Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Products: … ACTEMRA® CONCENTRADO PARA INFUNSION 80 MG/4ML ... ACTEMRA® CONCENTRADO PARA INFUSION 80 MG/4ML ... ACTEMRA® CONCENTRADO PARA INFUSION 200 MG/10ML …
Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label] . Fluticasone furoate was first approved in 2007 .
Approved
Matched Mixtures name: … RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓN ... RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓN …
Matched Products: … ARNUITY ELLIPTA100 MCG POLVO PARA INHALACION ... ARNUITY® ELLIPTA® 200 MCG POLVO PARA INHALACIÓN …
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Products: … AZBIOS® 1G POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... AZTREONAM 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Products: … GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 ML …
Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Products: … SULTALBAC® POLVO PARA RECONSTITUIR ... SULMIC® 250 MG/ 5ML POLVO PARA SUSPENSION ORAL. ... SULTAMICILINA 250 MG/5ML POLVO PARA SUSPENSIÓN …
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Products: … CEFADROXILO POLVO PARA SUSPENSIÓN 250 MG/5ML ... CEFADROXILO 250MG / 5ML POLVO PARA SUSPENSION ... CEFADROXILO 500 MG / 5 ML POLVO PARA SUSPENDER …
Displaying drugs 1 - 25 of 1334 in total