Dexibuprofen

DB09213ApprovedWithdrawnSmall molecule

Dexibuprofen is a pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation. It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties.

Chemical structure of Dexibuprofen
Mechanism
Curator reviewed · 1 reference
Primary indication
For more information, refer to ibuprofen.Curator reviewed · 6 structured indications
Formula / weight
C13H18O2 · 206.2808 g/mol (avg)
Also known as
d-ibuproten

Resolves to

Compound
UNII671DKG7P5SCAS51146-56-6ChEMBLCHEMBL175ChEBI43415PubChem39912KEGGD03715
Clinical / RWD
ATCM01AE14PharmGKBPA166049174
Structure
InChIKeyHEFNNWSXXWATRW-JTQLQIEISA-NSMILESCC(C)CC1=CC=C(C=C1)[C@H](C)C(O)=O
Targets
P35354PTGS2P23219PTGS1P10415BCL2P07204THBDP00750PLATP12104FABP2P37231PPARGP13569CFTR+4 more
Transporters
O15439ABCC4P33527ABCC1P46721SLCO1A2Q4U2R8SLC22A6Q8TCC7SLC22A8Q9NSA0SLC22A11O94956SLCO2B1P08183ABCB1

What you can answer from here — as of June 15, 2026

13Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
8TransportersSubstrate / inhibitor direction, not just membership
Listed above
1,611Drug interactionsStructured to mechanism, not free text
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5Clinical trialsPhase, status and sponsor resolved per trial
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6Structured indicationsCondition, population, route and combination as fields, not prose
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12ContraindicationsEach with its own population and attribute set
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104Marketed productsAcross 4 countries and 14 labellers
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1ATC codeIncluding every combination product, plus 21 drug categories
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54+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Dexibuprofen, and which of those have an active Phase 3 trial?

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