| DB00298 | Dapiprazole | approved | yes | antagonist | Details |
| DB00706 | Tamsulosin | approved, investigational | unknown | antagonist | Details |
| DB01403 | Methotrimeprazine | approved, investigational | unknown | antagonist | Details |
| DB00368 | Norepinephrine | approved | yes | agonist | Details |
| DB00590 | Doxazosin | approved | yes | antagonist | Details |
| DB01162 | Terazosin | approved | yes | antagonist | Details |
| DB00346 | Alfuzosin | approved, investigational | yes | antagonist | Details |
| DB04855 | Dronedarone | approved | yes | antagonist | Details |
| DB06144 | Sertindole | approved, investigational, withdrawn | unknown | | Details |
| DB05469 | R450 | investigational | unknown | | Details |
| DB05492 | Epicept NP-1 | investigational | unknown | | Details |
| DB06207 | Silodosin | approved | yes | antagonist | Details |
| DB06262 | Droxidopa | approved, investigational | yes | agonist | Details |
| DB06229 | Ocaperidone | investigational | unknown | | Details |
| DB00457 | Prazosin | approved | yes | antagonist | Details |
| DB00388 | Phenylephrine | approved | yes | agonist | Details |
| DB01186 | Pergolide | approved, investigational, vet_approved, withdrawn | unknown | agonist | Details |
| DB01200 | Bromocriptine | approved, investigational, withdrawn | unknown | agonist | Details |
| DB00622 | Nicardipine | approved, investigational | unknown | antagonist | Details |
| DB00321 | Amitriptyline | approved | no | antagonist | Details |
| DB00540 | Nortriptyline | approved | no | antagonist | Details |
| DB00458 | Imipramine | approved | no | antagonist | Details |
| DB00696 | Ergotamine | approved | yes | partial agonist | Details |
| DB01142 | Doxepin | approved, investigational | unknown | antagonist | Details |
| DB06694 | Xylometazoline | approved, investigational | unknown | agonist | Details |
| DB00668 | Epinephrine | approved, vet_approved | unknown | antagonist | Details |
| DB01136 | Carvedilol | approved, investigational | unknown | antagonist | Details |
| DB00575 | Clonidine | approved | unknown | agonist | Details |
| DB00800 | Fenoldopam | approved | unknown | inhibitor | Details |
| DB00248 | Cabergoline | approved | unknown | binder | Details |
| DB00211 | Midodrine | approved | unknown | agonist | Details |
| DB00723 | Methoxamine | approved, investigational | unknown | binder | Details |
| DB00925 | Phenoxybenzamine | approved | unknown | antagonist | Details |
| DB00935 | Oxymetazoline | approved, investigational | unknown | agonist | Details |
| DB09202 | Cirazoline | experimental | yes | partial agonist | Details |
| DB00692 | Phentolamine | approved | unknown | antagonist | Details |
| DB00908 | Quinidine | approved, investigational | unknown | antagonist | Details |
| DB00661 | Verapamil | approved | unknown | antagonist | Details |
| DB11124 | Racepinephrine | approved | yes | antagonist | Details |
| DB06153 | Pizotifen | approved | unknown | antagonist | Details |
| DB09128 | Brexpiprazole | approved, investigational | unknown | antagonist | Details |